Schrodinger, Inc.

SDGR Healthcare Health Information Services

Schrodinger, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $255.9 million, up 23.3% from fiscal 2024. In the quarter to June 2026, revenue grew 7.54%, EPS grew 113.6% and free cash flow grew 34.4%, each against the same quarter a year earlier.

22.60 2.88 −11.30%
Market cap
$1.9B
P/E
0.0×
Fwd P/E
−7.1×
Dividend yield
—
F-score
5/9
Altman Z
1.10
Beneish M
−3.47
Dividend safety
n/a

Insider Decisions trades per month

Total sells 2.21
Totals in millions of $.
Dec 25 Mar 26 Jun 26 Sep 26
Buy — — — — — — — — — — — —
Sell — — — 4 7 2 — — 1 — 1 —
Insider Ownership 15.28%

Capital & Financial Ratios $m

Market Cap 1,910.00
Revenue 259.04
Net Income (54.33)
Free Cash Flow (130.27)
Net Debt (418.80)
Current Ratio 2.71 (at or above 1.5: strong)
Debt/Equity 0.00 (at or below 0.5: strong)
P/E ratio 0.00
Fwd P/E (7.09) (negative: loss-making)
P/S ratio 6.52
P/B ratio 5.13
Past 5Y EPS Growth —
This Y EPS Growth (16.60%) (below 0%: weak)
Next Y EPS Growth 12.00%
Next Y revenue growth (5.62%) (below 0%: weak)
Next 5Y EPS Growth 13.73%

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/S against its own 10 years 20.50%
10-year low 10-year high
P/B against its own 10 years 71.69%
10-year low 10-year high
EV/Sales against its own 10 years 24.96%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2025 Powerpack
2024 Powerpack
2023 Powerpack
2022 Powerpack
2021 Powerpack
predictions special payouts not included in total or ratios

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 469 367 402 419
Receivables 89 255 104 41
Inventory — — — —
Other — — — —
568 635 519 470
2023 2024 2025 Q'26
Payables 17 11 11 10
ST’ Debt — — — —
Other — — — —
134 192 189 174

Compound Annual Growth %

10y 5y 3y
Sales — 18.81% 12.24%
Cash Flow — (3.67%) 0.00%
Earnings — 0.00% 0.00%
Book Value — (10.22%) (6.68%)

Revenue $m

Mar Jun Sep Dec Year
’26 59 59 — — —
’25 60 55 54 87 256
’24 37 47 35 88 208
’23 65 35 43 74 217
’22 49 38 37 57 181
’21 32 30 30 46 138
’20 26 23 26 33 108
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (15) (34) — — —
’25 144 (52) (62) (16) 14
’24 (39) (54) (33) (31) (157)
’23 (31) (18) (50) (37) (137)
’22 (40) (25) (30) (25) (120)
’21 (11) (29) (11) (20) (71)
’20 (6) (9) (12) 44 17
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (17) (34) — — —
’25 143 (53) (62) (16) 12
’24 (43) (55) (35) (32) (165)
’23 (35) (21) (55) (40) (150)
’22 (41) (27) (33) (26) (128)
’21 (11) (32) (13) (21) (78)
’20 (7) (10) (12) 43 14
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 (0.81) 0.08 — — —
’25 (0.82) (0.59) (0.45) 0.44 (1.41)
’24 (0.76) (0.74) (0.52) (0.55) (2.57)
’23 1.75 0.06 (0.86) (0.32) 0.54
’22 (0.48) (0.67) (0.56) (0.39) (2.10)
’21 0.00 (0.49) (0.49) (0.43) (1.42)
’20 (0.34) (0.05) 0.05 (0.18) (0.41)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1.6
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low — — — — 25.50 32.70 15.85 17.37 16.67 15.99

Analyst estimates 2026–2028

Powerpack
High — — — — 99.50 117.00 37.25 59.24 36.13 28.47
People
People Employees — — 394 394 452 664 787 867 891 850
Revenue/emp, $m — 0.00 0.17 0.22 0.24 0.21 0.23 0.25 0.23 0.30
Income, $m
Income, $m Revenue — 56 67 86 108 138 181 217 208 256
Gross margin, % — 71.39 64.43 57.39 58.72 47.57 55.83 64.93 63.64 55.74
EBT — (17) (28) (26) (26) (101) (149) 43 (186) (102)
EBT margin, % — (30.63) (42.54) (30.36) (24.32) (73.09) (82.41) 19.81 (89.48) (39.99)
Net income — 0 (28) (26) (27) (101) (149) 41 (187) (103)
Depreciation — 2 3 4 4 3 4 6 6 6
Per share, $
Per share, $ Revenue — 0.88 11.55 14.25 1.80 1.95 2.54 3.02 2.86 3.48
Earnings — (0.27) (4.93) (4.01) (0.41) (1.42) (2.10) 0.57 (2.57) (1.41)
Cash flow — (0.24) (4.11) (4.34) 0.28 (1.00) (1.68) (1.90) (2.17) 0.19
Capex — 0.00 (0.91) (0.31) (0.04) (0.10) (0.11) (0.19) (0.10) (0.02)
Free cash flow — (0.24) (5.02) (4.65) 0.24 (1.10) (1.79) (2.09) (2.27) 0.17
Book value — 0.58 15.62 16.36 10.40 7.89 6.29 7.64 5.80 4.96
Shares, m — 63 6 6 60 71 71 72 73 73
Valuation, ×
Valuation, × P/E — 0.00 0.00 0.00 0.00 0.00 0.00 61.31 0.00 0.00
P/S — 2.01 2.01 2.01 43.97 17.83 7.20 11.64 6.75 5.13
P/B — 0.00 0.00 0.00 7.62 4.41 2.91 4.60 3.33 3.61
EV/Sales — 1.00 1.00 1.00 38.02 13.63 4.68 9.47 4.98 3.56
EV/FCF — (3.07) (3.07) (3.07) 289.02 (24.14) (6.63) (13.67) (6.28) 73.12
Cash, $m
Cash, $m Operating cash flow — (15) (24) (26) 17 (71) (120) (137) (157) 14
Capex — (4) (5) (2) (3) (7) (8) (13) (7) (1)
Free cash flow — (15) (29) (28) 14 (78) (128) (150) (165) 12
Balance, $m
Balance, $m Working capital — 30 78 74 610 534 425 434 443 330
Total debt — — — 206 12 80 116 — — —
Net debt — (36) (84) (86) (643) (579) (456) (469) (367) (402)
Shareholders’ equity — 37 90 98 624 557 448 549 421 364
Returns, %
Returns, % ROA — (19.46) (47.09) (17.81) (5.43) (13.36) (20.65) 5.46 (23.01) (13.33)
ROIC — 0.00 (288.46) (202.87) 0.00 0.00 0.00 (138.97) (242.29) 0.00
ROE — 29.75 48.62 29.80 (9.22) (17.00) (29.69) 8.17 (38.58) (26.29)
Negative figures in brackets.

All 10 years →

Fiscal years to Dec 2025 · latest quarter Jun 2026

Charts ten years each

Schrodinger, Inc. vs peers in Health Information Services (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
HTFL Heartflow, Inc. $4.4B — (loss-making) — (loss-making) +47.57% (above 0%: growing) n/m +62.62% (above 0%: growing) 83.00% (27.93%) Compare
PRVA Privia Health Group, Inc. $2.9B 102× 87.8× +21.39% (above 0%: growing) +250.00% (above 0%: growing) −86.20% (below 0%: shrinking) 9.93% 1.86% Compare
SDGR Schrodinger, Inc. $1.9B — (loss-making) — (loss-making) +7.54% (above 0%: growing) n/m +34.43% (above 0%: growing) 55.07% (70.55%)
OMCL Omnicell, Inc. $1.6B 41.6× 55.1× +7.45% (above 0%: growing) +341.67% (above 0%: growing) +107.90% (above 0%: growing) 48.98% 10.39% Compare
CERT Certara, Inc. $1.5B — (loss-making) — (loss-making) +0.99% (above 0%: growing) n/m −78.46% (below 0%: shrinking) 62.34% (0.21%) Compare
GDRX GoodRx Holdings, Inc. $1.2B 62.7× 30.9× −1.31% (below 0%: shrinking) −25.00% (below 0%: shrinking) +112.45% (above 0%: growing) 89.52% 11.79% Compare
OMDA Omada Health, Inc. $1.1B 252× 143× +43.12% (above 0%: growing) n/m +45.71% (above 0%: growing) 72.62% 4.04% Compare
TDOC Teladoc Health, Inc. $1.1B — (loss-making) — (loss-making) −3.95% (below 0%: shrinking) n/m −27.07% (below 0%: shrinking) 68.56% (6.11%) Compare
HSTM HealthStream, Inc. $1.0B 46.0× 34.4× +12.55% (above 0%: growing) +27.78% (above 0%: growing) +362.71% (above 0%: growing) 65.35% 9.94% Compare
Median of peers $1.3B 62.7× 55.1× +10.00% +138.89% +54.17% 66.96% 2.95%

All 51 Health Information Services stocks →

Schrodinger, Inc. (SDGR) key facts

  • Strength: Schrodinger, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $255.9 million, up 23.3% from fiscal 2024.
  • Schrodinger, Inc. (SDGR) is a Health Information Services company in the Healthcare sector, listed on Nasdaq.
  • As of October 16, 2026, SDGR traded at $22.60, a market capitalization of $1.9 billion.
  • Return on equity was −26.3% and debt-to-equity 0.00.
  • Its Piotroski F-score is 5 out of 9 and its Altman Z-score is 1.10 (distress zone) for fiscal 2025.

Source: company filings (standardised) and stockrow calculations.

Schrodinger, Inc. (SDGR) Latest News

stockrow.com/SDGR · Data as of Jun 30, 2026 · For information only; not investment advice. · © 2026 stockrow.com