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Schrodinger, Inc.

SDGR Healthcare Health Information Services

Schrodinger, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $255.9 million, up 23.3% from fiscal 2024.

Revenue
+18.7%
EPS
−11.1%
Free cash flow
+21.6%

Quarter to September 2026, against a year earlier

29.96 1.19 +4.14%
Market cap
$2.2B
P/E
0.0×
Fwd P/E
−16.5×
Dividend yield
—
F-score
5/9
Altman Z
1.10
Beneish M
−3.47
Dividend safety
n/a
Overview
Financials
Income Statement Balance Sheet Cash Flow Metrics & Ratios

Insider Decisions last twelve months

Sold, $m 2.21
Trades a month
Jan 26 Apr 26 Jul 26 Oct 26
Buy — — — — — — — — — — — —
Sell — — 4 7 2 — — 1 — 1 — —
Insider Ownership 15.45%

Capital & Financial Ratios $m

Size
Market Cap 2,150.00
Revenue ttm 269.20
Net income ttm (59.25)
Free cash flow ttm (116.77)
Net debt Q (373.38)
Valuation
P/E 0.00
Forward P/E (16.50) (negative: loss-making)
Price / sales 8.05
Forward P/S Powerpack
Price / FCF 0.00
Price / book 7.18 (above 6: high)
Financial health
Current ratio Q 2.75 (at or above 1.5: strong)
Debt / equity Q 0.00 (at or below 0.5: strong)
Interest coverage Q (87.33)
Growth
Revenue growth Q +18.72% (above 0%: growing)
Operating income growth Q +43.13% (above 0%: growing)
EPS, this year −5.08% (below 0%: weak)
EPS, next year A +6.20%
Revenue, next year A −5.62% (below 0%: weak)
EPS, past 5 yrs —
EPS, next 5 yrs A +12.29%

Green and red mark values outside typical ranges; (Q) is the latest quarter, (A) analysts’ estimates. How we judge →

Valuation vs history

EV/Sales, ten years
EV/Sales is 6.7×, against a ten-year median of 7.1×; over the ten years it ranged from 1.7× in 2026 to 58.0× in 2020.
P/S against its own 10 years 35.12%
10-year low 10-year high
P/B against its own 10 years 84.10%
10-year low 10-year high
EV/Sales against its own 10 years 43.61%
10-year low 10-year high

Dividends

Yield
—
Annual rate
—
Payout ratio
—

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 469 367 402 373
Receivables 89 255 104 —
Inventory — — — —
Other — — — —
568 635 519 457
2023 2024 2025 Q'26
Payables 17 11 11 8
ST’ Debt — — — —
Other — — — —
134 192 189 166

Compound Annual Growth %

10y 5y 3y
Sales — 18.81% 12.24%
Cash Flow — (3.67%) 0.00%
Earnings — 0.00% 0.00%
Book Value — (10.22%) (6.68%)

Earnings Trends EPS, adjusted, against the consensus

Q3 FY26 Estimate −0.66 Actual −0.50

Earnings per share against the consensus, by quarter
Quarter Estimate Reported Result
Q4 FY25 −0.13 0.44 Beat by 0.57
Q1 FY26 −0.56 −0.81 Miss by 0.25
Q2 FY26 −0.60 0.08 Beat by 0.68
Q3 FY26 −0.66 −0.50 Beat by 0.16
Q4 FY26 −0.05 — Reports 24 February 2027

EPS $

Mar Jun Sep Dec Year
’26 (0.81) 0.08 (0.50) — —
’25 (0.82) (0.59) (0.45) 0.44 (1.41)
’24 (0.76) (0.74) (0.52) (0.55) (2.57)
’23 1.75 0.06 (0.86) (0.39) 0.54
’22 (0.48) (0.67) (0.56) (0.39) (2.10)
’21 0.00 (0.49) (0.49) (0.43) (1.42)
’20 (0.34) (0.05) 0.05 (0.18) (0.41)
Fiscal quarters ending in the months shown.

Revenue $m

Mar Jun Sep Dec Year
’26 59 59 64 — —
’25 60 55 54 87 256
’24 37 47 35 88 208
’23 65 35 43 74 217
’22 49 38 37 57 181
’21 32 30 30 46 138
’20 26 23 26 33 108
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (15) (34) (48) — —
’25 144 (52) (62) (16) 14
’24 (39) (54) (33) (31) (157)
’23 (31) (18) (50) (37) (137)
’22 (40) (25) (30) (25) (120)
’21 (11) (29) (11) (20) (71)
’20 (6) (9) (12) 44 17
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (17) (34) (49) — —
’25 143 (53) (62) (16) 12
’24 (43) (55) (35) (32) (165)
’23 (35) (21) (55) (40) (150)
’22 (41) (27) (33) (26) (128)
’21 (11) (32) (13) (21) (78)
’20 (7) (10) (12) 43 14
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1.6
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Ten-year view Analyst estimates Powerpack
Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 TTM Sep ’26 Trend 10 yrs 2026e 2027e 2028e Next 3/yr
Income, $m
Income, $m Revenue — 56 67 86 108 138 181 217 208 256 269 +21.0% 242 249 291 +4.4%
Gross margin, % — 71.39 64.43 57.39 58.72 47.57 55.83 64.93 63.64 55.74 58.52 (15.6) pt
EBT — (17) (28) (26) (26) (101) (149) 43 (186) (102) (57) +25.1%
EBT margin, % — (30.63) (42.54) (30.36) (24.32) (73.09) (82.41) 19.81 (89.48) (39.99) (21.12) (9.4) pt
Net income — 0 (28) (26) (27) (101) (149) 41 (187) (103) (59) n/m
Per share, $
Per share, $ Revenue — 0.88 11.55 14.25 1.80 1.95 2.54 3.02 2.86 3.48 3.60 +18.8%
Earnings — (0.27) (4.93) (4.01) (0.41) (1.42) (2.10) 0.57 (2.57) (1.41) (0.79) +23.0%
Cash flow — (0.24) (4.11) (4.34) 0.28 (1.00) (1.68) (1.90) (2.17) 0.19 (1.50) n/m
Capex — 0.00 (0.91) (0.31) (0.04) (0.10) (0.11) (0.19) (0.10) (0.02) (0.06) n/m
Free cash flow — (0.24) (5.02) (4.65) 0.24 (1.10) (1.79) (2.09) (2.27) 0.17 (1.56) n/m
Book value — 0.58 15.62 16.36 10.40 7.89 6.29 7.64 5.80 4.96 4.03 +30.6%
Shares, m — 63 6 6 60 71 71 72 73 73 74 +1.9%
Valuation, ×
Valuation, × P/E — 0.00 0.00 0.00 0.00 0.00 0.00 61.31 0.00 0.00 0.00 6.8
P/S — 2.01 2.01 2.01 43.97 17.83 7.20 11.64 6.75 5.13 8.05 11.0
P/B — 0.00 0.00 0.00 7.62 4.41 2.91 4.60 3.33 3.61 7.18 2.9
EV/Sales — 1.00 1.00 1.00 38.02 13.63 4.68 9.47 4.98 3.56 6.67 8.6
EV/FCF — (3.07) (3.07) (3.07) 289.02 (24.14) (6.63) (13.67) (6.28) 73.12 (15.37) 33.6
Cash, $m
Cash, $m Operating cash flow — (15) (24) (26) 17 (71) (120) (137) (157) 14 (113) n/m
Capex — (4) (5) (2) (3) (7) (8) (13) (7) (1) (4) (11.1%)
Free cash flow — (15) (29) (28) 14 (78) (128) (150) (165) 12 (117) n/m
Balance, $m
Balance, $m Working capital — 30 78 74 610 534 425 434 443 330 290 +34.8%
Net debt — (36) (84) (86) (643) (579) (456) (469) (367) (402) (373) +35.1%
Shareholders’ equity — 37 90 98 624 557 448 549 421 364 302 +33.1%
Returns, %
Returns, % ROA — (19.46) (47.09) (17.81) (5.43) (13.36) (20.65) 5.46 (23.01) (13.33) (9.36) +6.1 pt
ROIC — 0.00 (288.46) (202.87) 0.00 0.00 0.00 (138.97) (242.29) 0.00 0.00 0.0 pt
ROE — 29.75 48.62 29.80 (9.22) (17.00) (29.69) 8.17 (38.58) (26.29) (19.02) (56.0) pt
People
People Employees — — 394 394 452 664 787 867 891 850 — +11.6%
Revenue/emp, $m — 0.00 0.17 0.22 0.24 0.21 0.23 0.25 0.23 0.30 — n/m
Negative figures in brackets.
estimates

All 10 years →

Fiscal years to Dec 2025 · latest quarter Sep 2026 · fundamentals updated 4 Nov 2026

Schrodinger, Inc. vs peers in Health Information Services (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
HTFL Heartflow, Inc. $4.5B — (loss-making) — (loss-making) +47.57% (above 0%: growing) n/m +62.62% (above 0%: growing) 83.00% (27.93%) Compare
PRVA Privia Health Group, Inc. $3.1B 88.3× 83.4× +13.19% (above 0%: growing) +83.33% (above 0%: growing) −44.35% (below 0%: shrinking) 0.00% 3.13% Compare
SDGR Schrodinger, Inc. $2.2B — (loss-making) — (loss-making) +18.72% (above 0%: growing) n/m +21.64% (above 0%: growing) 59.32% (40.52%)
CERT Certara, Inc. $1.9B — (loss-making) — (loss-making) −9.29% (below 0%: shrinking) +300.00% (above 0%: growing) −12.09% (below 0%: shrinking) 66.87% 2.45% Compare
OMCL Omnicell, Inc. $1.7B 39.0× 32.9× −0.89% (below 0%: shrinking) +100.50% (above 0%: growing) +42.62% (above 0%: growing) 44.77% 4.85% Compare
TDOC Teladoc Health, Inc. $1.7B — (loss-making) — (loss-making) −3.41% (below 0%: shrinking) n/m +11.76% (above 0%: growing) 68.56% (4.64%) Compare
GDRX GoodRx Holdings, Inc. $1.2B 65.7× 46.0× −1.31% (below 0%: shrinking) −25.00% (below 0%: shrinking) +112.45% (above 0%: growing) 89.52% 11.79% Compare
OMDA Omada Health, Inc. $1.2B 267× 156× +43.12% (above 0%: growing) n/m +45.71% (above 0%: growing) 72.62% 4.04% Compare
HSTM HealthStream, Inc. $905.6M 42.0× 45.4× +8.94% (above 0%: growing) −8.90% (below 0%: shrinking) −4.80% (below 0%: shrinking) 63.98% 7.91% Compare
Median of peers $1.7B 65.7× 46.0× +4.02% +83.33% +27.19% 67.71% 3.59%

All 44 Health Information Services stocks →

Pay and ownership Proxy statement filed 28 April 2026

Chief executive’s pay

Year Total pay Actually paid $100 invested
2025 4.08m 3.21m 22.58
2024 4.41m 667.05k 24.36
2023 3.12m 9.66m 45.21
2022 3.92m (3.05m) 23.60
2021 8.49m (21.06m) 43.99
Total pay is as the Summary Compensation Table states it; actually paid revalues the year’s share awards at its end, as the SEC’s pay-versus-performance rule asks. $100 invested is what $100 in the company’s shares at the start of the earliest year shown was worth at each year’s end. Read the proxy statement

Schrodinger, Inc. (SDGR) Latest News

5 Nov

Impact 3 · · Moby
Impact 3 · · GuruFocus.com

4 Nov

Impact 3 · · MarketBeat transcript
Impact 3 · · Business Wire

28 Oct

Impact 4 · · Simply Wall St.
Impact 3 · · Zacks

21 Oct

Impact 3 · · Business Wire

14 Oct

Impact 4 · · Business Wire

13 Oct

Impact 3 · · Simply Wall St.

8 Oct

Impact 3 · · Trefis

6 Oct

Impact 4 · · Zacks

27 Sep

Impact 3 · · Simply Wall St.

24 Sep

Impact 3 ·

23 Sep

Impact 3 · · Barchart

9 Sep

Impact 3 ·

6 Aug

Impact 4 ·
Impact 4 · transcript
Impact 3 · · MarketBeat transcript

5 Aug

Impact 4 ·
Impact 3 ·
Impact 3 ·

27 Jul

Impact 4 ·

30 Jun

Impact 4 · · 24/7 Wall St.

21 Jun

Impact 3 ·

8 May

Impact 4 · · Simply Wall St.

6 May

Impact 4 · · Simply Wall St.
Impact 4 · · Moby

5 May

Impact 3 · · MarketBeat
Impact 3 · · Zacks
Impact 3 · · Business Wire

SDGR metrics, ten years each

stockrow.com/SDGR · Data as of Nov 4, 2026 · For information only; not investment advice. · © 2026 stockrow.com