Madrigal Pharmaceuticals, Inc.
MDGL Healthcare Biotechnology
Madrigal Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $958.4 million, up 432.1% from fiscal 2024.
- Revenue
- +50.1%
- EPS
- +147.3%
- Free cash flow
- +53.5%
- Total debt
- +0.45%
Quarter to September 2026, against a year earlier
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Madrigal Pharmaceuticals, Inc. (MDGL) Operating margin
Madrigal Pharmaceuticals, Inc.'s operating margin over the twelve months to 30 September 2026 was −10.7%, up 20.6 percentage points from fiscal 2025 (−31.3%). Over the past ten years it has ranged from −276.4% (fiscal 2024) to 0.00% (fiscal 2023); the current reading is higher than 18% of that period. That is below the Biotechnology industry median of 0.00% and below the Healthcare sector median of 0.00%.
Operating margin, annual
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Annual newest first
| Period | Operating margin | Change (points) |
|---|---|---|
| FY2025 | −31.3% | 245.08 |
| FY2024 | −276.4% | (276.39) |
| FY2023 | 0.00% | 0.00 |
| FY2022 | 0.00% | 0.00 |
| FY2021 | 0.00% | 0.00 |
| FY2020 | 0.00% | 0.00 |
| FY2019 | 0.00% | 0.00 |
| FY2018 | 0.00% | 0.00 |
| FY2017 | 0.00% | 0.00 |
| FY2016 | 0.00% | 0.00 |
Quarterly newest first
| Period | Operating margin | Change (points) |
|---|---|---|
| Sep 2026 | 13.0% | 28.44 |
| Jun 2026 | −15.5% | 14.32 |
| Mar 2026 | −29.8% | (11.22) |
| Dec 2025 | −18.6% | 21.12 |
| 43 more quarters | Free account |
Against its own ten years
Operating margin against peers
| Company | Operating margin |
|---|---|
| KRYS Krystal Biotech, Inc. compare | 48.4% |
| PTGX Protagonist Therapeutics, Inc. compare | 20.7% |
| TGTX TG Therapeutics, Inc. compare | 17.1% |
| CAI Caris Life Sciences,�Inc. compare | 13.4% |
| SYRE Spyre Therapeutics, Inc. compare | 0.00% |
| MDGL Madrigal Pharmaceuticals, Inc. | −10.7% |
| TWST Twist Bioscience Corporation compare | −33.6% |
| IBRX ImmunityBio, Inc. compare | −151.9% |
| CYTK Cytokinetics, Incorporated compare | −625.2% |
| Biotechnology industry median | 0.00% |
| Healthcare sector median | 0.00% |
| Market median | 0.00% |
What Operating margin is
EBIT Margin tells an investor how much operating profit, before interest and taxes, a company keeps from each unit of revenue.
EBIT ÷ Revenue
More on MDGL
- Revenue
- Net income
- EPS (diluted)
- EBITDA
- Free cash flow
- Operating cash flow
- Gross margin
- Net margin
- Free cash flow margin
- P/E ratio
- P/S ratio
- P/B ratio
- Price to free cash flow
- EV/EBITDA
- EV/Sales
- EV/FCF
- Return on equity
- Return on assets
- Return on invested capital
- Debt to equity
- Current ratio
- Total debt
- Shares outstanding
- Book value per share
- Revenue growth
- The full statement