Madrigal Pharmaceuticals, Inc.

MDGL Healthcare Biotechnology

Madrigal Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $958.4 million, up 432.1% from fiscal 2024.

Revenue
+50.1%
EPS
+147.3%
Free cash flow
+53.5%
Total debt
+0.45%

Quarter to September 2026, against a year earlier

390.52 9.58 −2.39%
Market cap
$9.3B
P/E
0.0×
Fwd P/E
−68.8×
Dividend yield
—
F-score
n/a
Altman Z
10.48
Beneish M
0.50
Dividend safety
n/a

Madrigal Pharmaceuticals, Inc. (MDGL) Return on invested capital

Alert me on Return on invested capital

Madrigal Pharmaceuticals, Inc.'s return on invested capital over the twelve months to 30 September 2026 was −1,480.3%, down 1480.3 percentage points from fiscal 2025 (0.00%). Over the past ten years it has ranged from 0.00% (fiscal 2025) to 0.00% (fiscal 2025) — the current reading is the highest in ten years. That is below the Biotechnology industry median of 0.00% and below the Healthcare sector median of 0.00%.

Return on invested capital, annual

Embed this chart

Annual newest first

Period Return on invested capital Change (points)
FY2025 0.00% 0.00
FY2024 0.00% 0.00
FY2023 0.00% 0.00
FY2022 0.00% 0.00
FY2021 0.00% 0.00
FY2020 0.00% 0.00
FY2019 0.00% 0.00
FY2018 0.00% 0.00
FY2017 0.00% 0.00
FY2016 0.00% 0.00

Against its own ten years

Low 0.00% High 0.00%
Ten-year median 0.00%
Current reading's percentile 100

Return on invested capital against peers

Company Return on invested capital
PTGX Protagonist Therapeutics, Inc. compare 61.8%
KRYS Krystal Biotech, Inc. compare 27.2%
CAI Caris Life Sciences,�Inc. compare 22.2%
TGTX TG Therapeutics, Inc. compare 10.7%
IBRX ImmunityBio, Inc. compare 0.00%
CYTK Cytokinetics, Incorporated compare 0.00%
SYRE Spyre Therapeutics, Inc. compare 0.00%
TWST Twist Bioscience Corporation compare −30.8%
MDGL Madrigal Pharmaceuticals, Inc. −1,480.3%
Biotechnology industry median 0.00%
Healthcare sector median 0.00%
Market median 0.00%

What Return on invested capital is

Return on Invested Capital shows how much after-tax operating profit a company earns on the money its lenders and shareholders have put in.

TTM: (Operating Income × 0.625) ÷ (Shareholders Equity (Total) (latest quarter) + Long Term Debt (Total) (latest quarter) + Current Part of Debt (latest quarter) − Cash & Short Term Investments (latest quarter)); Annual: (Operating Income × 0.625) ÷ (Shareholders Equity (Total) + Long Term Debt (Total) + Current Part of Debt − Cash & Short Term Investments)

The full definition of Return on invested capital →

More on MDGL