Halozyme Therapeutics, Inc.

HALO Healthcare Biotechnology

Halozyme Therapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $1.4 billion, up 37.6% from fiscal 2024.

Revenue
+39.2%
EPS
+45.6%
Free cash flow
−58.6%
Total debt
+115.1%

Quarter to September 2026, against a year earlier

103.92 19.04 −15.48%
Market cap
$14.0B
P/E
29.5×
Fwd P/E
17.9×
Dividend yield
—
F-score
5/9
Altman Z
3.46
Beneish M
−2.59
Dividend safety
n/a

Halozyme Therapeutics, Inc. (HALO) Operating margin

Alert me on Operating margin

Halozyme Therapeutics, Inc.'s operating margin over the twelve months to 30 September 2026 was 37.4%, up 3.8 percentage points from fiscal 2025 (33.6%). Over the past ten years it has ranged from −56.7% (fiscal 2016) to 62.2% (fiscal 2021); the current reading is higher than 55% of that period. That is above the Biotechnology industry median of 0.00% and above the Healthcare sector median of 0.00%.

Operating margin, annual

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Annual newest first

Period Operating margin Change (points)
FY2025 33.6% (20.74)
FY2024 54.3% 13.61
FY2023 40.7% 0.18
FY2022 40.5% (21.71)
FY2021 62.2% 8.33
FY2020 53.9% 88.41
FY2019 −34.5% 11.15
FY2018 −45.7% (71.23)
FY2017 25.6% 82.30
FY2016 −56.7% (36.39)

Quarterly newest first

Period Operating margin Change (points)
Sep 2026 59.8% 0.03
Jun 2026 59.8% 10.82
Mar 2026 49.0% 69.54
Dec 2025 −20.6% (82.07)
43 more quarters

Against its own ten years

Low −56.7% High 62.2%
Ten-year median 33.6%
Current reading's percentile 56

Operating margin against peers

Company Operating margin
EXEL Exelixis, Inc. compare 40.2%
HALO Halozyme Therapeutics, Inc. 37.4%
ASND Ascendis Pharma A/S compare 24.8%
TECH Bio-Techne Corp compare 20.7%
JAZZ Jazz Pharmaceuticals PLC compare 9.03%
BMRN BioMarin Pharmaceutical Inc. compare 3.12%
SMMT Summit Therapeutics PLC compare 0.00%
KYMR Kymera Therapeutics, Inc. compare 0.00%
BBIO BridgeBio Pharma, Inc. compare −38.5%
Biotechnology industry median 0.00%
Healthcare sector median 0.00%
Market median 0.00%

What Operating margin is

EBIT Margin tells an investor how much operating profit, before interest and taxes, a company keeps from each unit of revenue.

EBIT ÷ Revenue

The full definition of Operating margin →

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