Madrigal Pharmaceuticals, Inc.

MDGL Healthcare Biotechnology

Madrigal Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $958.4 million, up 432.1% from fiscal 2024.

Revenue
+50.1%
EPS
+147.3%
Free cash flow
+53.5%
Total debt
+0.45%

Quarter to September 2026, against a year earlier

396.86 3.24 −0.81%
Market cap
$9.3B
P/E
0.0×
Fwd P/E
−68.8×
Dividend yield
—
F-score
n/a
Altman Z
10.48
Beneish M
0.50
Dividend safety
n/a

Madrigal Pharmaceuticals, Inc. (MDGL) Return on equity

Alert me on Return on equity

Madrigal Pharmaceuticals, Inc.'s return on equity over the twelve months to 30 September 2026 was −24.8%, up 17.7 percentage points from fiscal 2025 (−42.5%). Over the past ten years it has ranged from −150.1% (fiscal 2022) to 422.1% (fiscal 2016); the current reading is higher than 64% of that period. That is above the Biotechnology industry median of −50.1% and above the Healthcare sector median of −26.3%.

Return on equity, annual

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Annual newest first

Period Return on equity Change (points)
FY2025 −42.5% 37.86
FY2024 −80.4% 43.63
FY2023 −124.0% 26.14
FY2022 −150.1% (39.20)
FY2021 −110.9% (49.31)
FY2020 −61.6% (42.82)
FY2019 −18.8% (8.84)
FY2018 −9.95% 18.54
FY2017 −28.5% (450.58)
FY2016 422.1% 506.48

Against its own ten years

Low −150.1% High 422.1%
Ten-year median −61.6%
Current reading's percentile 64

Return on equity against peers

Company Return on equity
CYTK Cytokinetics, Incorporated compare 184.7%
IBRX ImmunityBio, Inc. compare 122.9%
TGTX TG Therapeutics, Inc. compare 100.3%
KRYS Krystal Biotech, Inc. compare 17.5%
PTGX Protagonist Therapeutics, Inc. compare 11.0%
CAI Caris Life Sciences,�Inc. compare 0.00%
MDGL Madrigal Pharmaceuticals, Inc. −24.8%
TWST Twist Bioscience Corporation compare −29.6%
SYRE Spyre Therapeutics, Inc. compare −41.2%
Biotechnology industry median −50.1%
Healthcare sector median −26.3%
Market median 0.51%

What Return on equity is

ROE shows how much profit a company earns for its shareholders on the equity they have in the business.

Annual: Net Income Allotted to Shareholders ÷ Average Common Equity; TTM: Net Income Allotted to Shareholders ÷ Average Common Equity (latest quarter)

The full definition of Return on equity →

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