Ascendis Pharma A/S ASND

225.60 (5.10) (2.21%) as of 25 Sep
Market cap
$15.7B
P/E
16.3×
Growth Flags show if company had growth for consecutive years,
Insider Buys alert about insiders buying in the last 12 month

Insider Decisions

Total buys 0.78
Total sells 5.45
in millions of $
Nov 25 Feb 26 May 26 Aug 26
Buy — — — — — — — 3 1 — 1 —
Sell — — — — — — — 1 — — — 1
Insider Ownership 0.00%

Capital & Financial Ratios

Market Cap 15,680.00
Revenue 1,212.10
Net Income 865.91
Free Cash Flow 387.49
Net Debt (421.11)
Current Ratio 2.99
Debt/Equity 0.31
P/E ratio 16.27
P/S ratio 11.98
P/B ratio 8.69
Past 5Y EPS Growth (6.13%)
This Y EPS Growth 475.31%
Next Y EPS Growth (35.16%)
Next 5Y EPS Growth 38.10%
in millions of $

Dividends

Payout Ratio 0.00
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2023 Powerpack
2022 Powerpack
2021 Powerpack
2020 Powerpack
2019 Powerpack
predictions in italic, special payouts not included in total or ratios

Assets vs Liabilities

2023 2024 2025 Q'26
Cash 432 605 697 944
Receivables 60 192 178 261
Inventory 226 320 341 361
Other — — — —
761 1,148 1,255 1,617
2023 2024 2025 Q'26
Payables 102 104 103 121
ST’ Debt 12 532 550 76
Other 81 345 550 329
214 982 1,210 541
in millions of $

Compound Annual Growth

10y 5y 3y
Sales 56.90% 152.47% 147.23%
Cash Flow 0.00% 0.00% 0.00%
Earnings 0.00% 0.00% 0.00%
Book Value 0.00% 0.00% 0.00%

Revenue

Mar Jun Sep Dec Year
’26 289 394 — — —
’25 106 179 250 279 815
’24 104 39 64 187 393
’23 36 52 52 149 289
’22 8 7 15 24 54
’21 1 1 1 6 9
’20 2 2 3 1 8
in millions of $ · fiscal quarters ending in the months shown

Operating Cash Flow

Mar Jun Sep Dec Year
’26 (9) 328 — — —
’25 (15) (10) 2 84 61
’24 (110) (65) (65) (91) (331)
’23 (158) (169) (135) (43) (506)
’22 (147) (125) (85) (166) (522)
’21 (98) (139) (110) (147) (494)
’20 (74) (62) (76) (98) (310)
in millions of $ · fiscal quarters ending in the months shown

Free Cash Flow

Mar Jun Sep Dec Year
’26 (18) 324 — — —
’25 (16) (14) 2 80 51
’24 (111) (64) (66) (91) (332)
’23 (159) (170) (136) (43) (508)
’22 (147) (123) (88) (170) (527)
’21 (116) (131) (123) (153) (523)
’20 (80) (68) (78) (103) (329)
in millions of $ · fiscal quarters ending in the months shown

EPS

Mar Jun Sep Dec Year
’26 11.41 3.29 — — —
’25 (1.66) (0.69) (1.17) (0.64) (4.25)
’24 (2.48) (2.05) (1.89) (0.68) (7.07)
’23 (2.12) (2.35) (3.12) (1.66) (9.24)
’22 (2.48) (1.54) (3.05) (3.78) (10.96)
’21 (1.41) (3.01) (1.73) (2.14) (8.28)
’20 (1.46) (2.17) (2.70) (3.15) (9.46)
fiscal quarters ending in the months shown

Target Price Range

Analyst price targets

Recommendation Rating

1.1
1Buy 2 3Hold 4 5Sell
2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 2027 2028
11.92 19.60 38.28 59.58 92.00 109.36 61.58 64.33 111.09 118.03

Analyst estimates 2026–2028

Powerpack
Low Price
21.79 42.00 76.99 140.15 183.98 178.71 137.40 129.43 161.00 229.94
High Price
101 137 216 330 482 639 797 879 1,017 1,189
Employees
0 0 0 0 0 0 0 0 0 1
Revenue/Emp
5 2 12 15 8 9 54 289 393 815
Revenue
100.00% 100.00% 100.00% 100.00% 100.00% 54.71% 76.28% 83.36% 87.83% 86.82%
Gross Margin
(76) (141) (154) (244) (479) (454) (609) (513) (404) (241)
EBT
(1,492.23%) (8,128.83%) (1,233.25%) (1,631.78%) (6,028.69%) (4,936.26%) (1,129.12%) (177.77%) (102.64%) (29.53%)
EBT Margin
(76) (140) (154) (244) (479) (454) (614) (521) (409) (258)
Net Income
1 1 1 7 11 18 19 20 19 20
Depreciation
0.19 0.05 0.30 0.32 0.16 0.17 0.96 5.13 6.80 13.44
Revenue/Sh
(2.85) (4.33) (3.74) (5.25) (9.46) (8.28) (10.96) (9.24) (7.07) (4.25)
Earnings/Sh
(2.51) (3.20) (3.99) (4.24) (6.13) (9.02) (9.31) (8.99) (5.72) 1.01
Cash Flow/Sh
(0.03) (0.03) (0.08) (0.12) (0.37) (0.52) (0.09) (0.05) (0.01) (0.16)
Capex/Sh
(2.53) (3.23) (4.07) (4.36) (6.50) (9.54) (9.41) (9.03) (5.73) 0.85
Free CF/Sh
7.36 6.29 8.05 14.38 18.93 19.09 4.95 (2.80) (1.98) (3.04)
Book Value/Sh
27 34 41 47 51 55 56 56 58 61
Shares
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
PE Ratio
103.77 773.87 205.98 431.91 1,062.89 800.73 125.55 24.87 20.25 15.86
PS Ratio
2.71 6.32 7.78 9.67 8.81 7.05 24.40 0.00 0.00 0.00
PB Ratio
64.62 646.19 179.72 389.93 973.61 725.97 121.11 25.41 21.07 16.22
EV/Sales
(4.89) (10.29) (13.44) (28.80) (23.50) (12.78) (12.38) (14.43) (24.99) 257.17
EV/FCF
(67) (107) (164) (197) (310) (494) (522) (506) (331) 61
Op' Cash Flow
(1) (1) (3) (6) (19) (29) (5) (3) (1) (10)
Capex
(67) (109) (167) (203) (329) (523) (527) (508) (332) 51
FCF
189 204 300 631 785 835 793 547 166 45
Working Cap'
— — — 41 112 119 536 590 927 986
Total Debt
(200) (221) (328) (629) (709) (688) (239) 158 321 289
Net Debt
195 212 331 669 958 1,045 277 (158) (114) (184)
Sh' Equity
(42.51%) (62.41%) (49.95%) (43.04%) (50.99%) (37.77%) (50.54%) (51.04%) (37.71%) (18.76%)
ROA
0.00% 0.00% (4,420.67%) (397.86%) (94.80%) (93.45%) (968.11%) (84,748.35%) (91.04%) (91.65%)
ROIC
(46.08%) (68.81%) (56.66%) (48.86%) (58.84%) (45.30%) (92.90%) (870.08%) 300.75% 172.80%
ROE
predictions in italic, sparklines do not include predictions

All 10 years →

Fiscal years to Dec 2025 · latest quarter Jun 2026

Ascendis Pharma A/S (ASND) key facts

  • Ascendis Pharma A/S (ASND) is a Biotechnology company in the Healthcare sector, traded in the US as an ADR.
  • Ascendis Pharma A/S’s revenue for fiscal 2025 (year ended December 2025) was $814.8 million, up 107.1% from fiscal 2024.
  • Ascendis Pharma A/S reported a net loss of $258.0 million, or a loss of $4.25 per share, for fiscal 2025.
  • As of September 25, 2026, ASND traded at $225.60, a market capitalization of $15.7 billion.
  • At that price the stock trades at 16.3× trailing-twelve-month earnings and 12.0× sales.
  • Return on equity was 172.8% and debt-to-equity 0.31.

Source: company filings (standardised) and stockrow calculations.

Ascendis Pharma A/S (ASND) Latest News

News by impact score

Fine-tune

20 Sep

3

Ascendis Pharma A/S announced a board-authorized buyback of up to $400 million of ordinary shares. The plan is optional and can be paused or altered, depending on market conditions. In the quarter ended June 30, product revenue rose to €315 million, up 105% YoY, led by YORVIPATH at €252 million. Operating profit swung to €220 million from a year-ago loss, helped by a €158 million sale of a priority-review voucher; non-IFRS €92 million. First-half 2026 operating cash flow reached €274 million; cash on hand was €812 million as of June 30. All €575 million of convertible notes converted on May 6, removing debt to equity. Costs rose with expansion: SG&A €173 million and R&D up. Short interest about 7.6%; forward P/E near 21. The buyback’s ceiling is not a commitment; actual action will depend on pricing and conditions, with the business still reliant on YORVIPATH and newer launches like YUVIWEL. Buyback is a non-binding option signaling confidence but unlikely to drastically alter trajectory; core risks and growth drivers remain in product demand and costs.

19 Sep

4

Ascendis Pharma (ASND) regains exclusive rights to key TransCon metabolic programs. Regaining exclusive rights to key TransCon metabolic programs strengthens pipeline control and revenue potential.

17 Sep

4

Ascendis Pharma will regain rights to its metabolic drug, prompting questions on whether the benefits of greater ownership outweigh the costs. Regaining full ownership of metabolic drug rights can substantially alter Ascendis Pharma's development path and market position.

16 Sep

3

Ascendis Pharma terminated collaboration with Novo Nordisk. Wedbush states Ascendis has capacity to execute alone. Termination of Novo Nordisk collaboration enables independent execution per Wedbush view.

15 Sep

4

Ascendis Pharma regains rights to obesity drug and discloses $400 million share buyback. Regaining obesity drug rights plus large buyback represent major strategic moves likely to shift company trajectory and investor sentiment.

14 Sep

4

Ascendis Pharma regains rights to TransCon technology in metabolic and cardiovascular diseases. Regaining full control of TransCon technology in core therapeutic areas strengthens Ascendis strategic positioning and development options.

3

Ascendis Pharma A/S announces a planned $400 million share repurchase program. A $400 million share repurchase program signals management confidence and can support stock price through reduced share count.

10 Sep

4

Ascendis Pharma A/S announced its growth drug shows benefits in infants. Positive trial data on growth drug benefits in infants signals major pipeline progress and potential regulatory gains for Ascendis.

9 Sep

3

Ascendis Pharma presented first infant data from its clinical trial of once-weekly TransCon CNP (Navepegritide) at ESPE 2026. Initial infant trial data for Navepegritide signals pipeline progress that may affect Ascendis' product development outlook.

4 Sep

4

Ascendis Pharma secures reimbursement approval, refocusing attention on its fair value narrative and potential market performance. Reimbursement approval improves product access and supports stronger revenue trajectory for Ascendis Pharma.

3

BioMarin secured 20% U.S. royalties on Yuviwel, prompting questions on whether monetizing a rival outperforms blocking it, with direct revenue implications for Ascendis Pharma as the product's developer. Royalties on Yuviwel directly reduce Ascendis net product revenue and margins.

3

Ascendis Pharma settles patent dispute and secures Canadian reimbursement approval for Yorvipath. Patent settlement removes litigation risk while Canadian reimbursement opens new revenue stream for Yorvipath.

3 Sep

3

BioMarin converted a competitive threat linked to Ascendis Pharma into a royalty-bearing asset. BioMarin royalty structure may moderately affect Ascendis competitive positioning and market dynamics.

31 Aug

4

Biomarin and Ascendis Pharma reached a mutually beneficial agreement ending all global patent disputes. Ending patent disputes removes legal risks and frees Ascendis resources for pipeline advancement.

3

ASND and BMRN stocks rose as analysts called patent peace a clean overhang lift, though ratings stayed unchanged. Patent resolution lifts overhang and lifts stocks for ASND but leaves analyst ratings unchanged.

3

Ascendis Pharma and BioMarin have entered a binding term sheet for a global settlement and license agreement related to YUVIWEL (Navepegritide). Settlement and license terms may moderately stabilize Ascendis operations and product positioning without fundamentally altering long-term trajectory.

25 Aug

3

Ascendis Pharma will deliver an oral presentation of week 104 data from the pivotal trial of TransCon CNP (Navepegritide) at ISDS 2026. Long-term pivotal data presentation for lead pipeline asset may moderately shift sentiment around future approval prospects.

21 Aug

4

Ascendis Pharma is advancing three new drugs that position the company for accelerated growth in biotechnology. Three new drug developments signal major strategic progress likely to boost long-term performance and investor outlook.

20 Aug

4 transcript

Ascendis Pharma A/S (ASND) released its Q2 2026 earnings call transcript detailing financial results and business updates. Q2 2026 earnings and forward outlook can significantly shift investor views and company trajectory.

4

Ascendis Pharma reported earnings and clinical trial updates, with analysis questioning if the stock price fully reflects these developments. Earnings results and trial updates directly affect revenue forecasts and valuation for Ascendis Pharma.

14 Aug

4

Ascendis Pharma reports solid Yorvipath quarter performance while Yuviwel launches with strong initial uptake, according to RBC. Solid product sales and launch momentum for Yorvipath and Yuviwel signal meaningful revenue growth and market traction for Ascendis.

13 Aug

4

Ascendis Pharma AS doubled revenue to EUR315 million in Q2 2026 amid continued product development progress. Doubled revenue reflects strong commercial traction that can materially lift valuation and growth outlook.

3 transcript

Ascendis Pharma A/S held its Q2 earnings call, covering financial results, pipeline progress, revenue figures, and strategic outlook for the biotech company. Quarterly earnings updates typically provide financial and pipeline details that moderately influence near-term stock sentiment and valuation.

3

Ascendis Pharma A/S reported its second quarter 2026 financial results. Quarterly financial results provide data that can shift valuation and near-term investor sentiment.

6 Aug

4

Ascendis Pharma A/S reports COACH Week 78 results and updates on achondroplasia programs plus YUVIWEL uptake in the U.S. Clinical data releases and product uptake updates signal major advancements in achondroplasia treatment and revenue potential.

14 Jul

3

FDA accepts BioMarin’s sNDA seeking full approval for Voxzogo. Competitor BioMarin’s potential full Voxzogo approval directly challenges Ascendis’ achondroplasia franchise.

12 Jul

4

Ascendis Pharma (ASND) reported two-year YUVIWEL trial data in achondroplasia. Two-year achondroplasia trial data can drive major regulatory and commercial shifts for Ascendis Pharma's key asset.

30 Jun

4

Ascendis Pharma's TransCon CNP treatment for children with achondroplasia demonstrated continued improvements in lower extremity alignment at week 104 in the pivotal ApproaCH trial. Long-term positive ApproaCH trial data bolsters TransCon CNP efficacy and Ascendis regulatory and commercial outlook.

13 Jun

4

Ascendis Pharma's Phase 3 data show TransCon PTH replicated endogenous PTH systemic actions through week 182 in adults with hypoparathyroidism. Positive long-term Phase 3 results for TransCon PTH in hypoparathyroidism strengthen approval and commercial prospects.

11 Jun

4

Ascendis Pharma A/S reported TransCon PTH sustained efficacy at five years. Five-year efficacy data for TransCon PTH strengthens approval odds and commercial outlook.

stockrow.com/ASND · Data as of Jun 30, 2026 · For information only; not investment advice. · © 2026 stockrow.com