Kymera Therapeutics, Inc.

KYMR Healthcare Biotechnology

Kymera Therapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $39.2 million, down 16.7% from fiscal 2024.

Revenue
+466.4%
EPS
−40.3%
Free cash flow
−186.6%
Total debt
−66.6%

Quarter to September 2026, against a year earlier

130.92 2.80 +2.19%
Market cap
$10.9B
P/E
0.0×
Fwd P/E
−31.6×
Dividend yield
—
F-score
4/9
Altman Z
23.22
Beneish M
n/a
Dividend safety
n/a

Insider Decisions last twelve months

Bought, $m 172.50
Sold, $m 473.29
Trades a month
Jan 26 Apr 26 Jul 26 Oct 26
Buy 1 — — — — — — — — — — —
Sell 6 1 2 9 7 2 11 3 — 1 1 —
Insider Ownership 23.39%

Capital & Financial Ratios $m

Size
Market Cap 10,940.00
Revenue ttm 105.00
Net income ttm (349.42)
Free cash flow ttm (288.89)
Net debt Q (970.61)
Valuation
P/E 0.00
Forward P/E (31.60) (negative: loss-making)
Price / sales 119.82 (above 10: high)
Forward P/S Powerpack
Price / FCF 0.00
Price / book 7.79 (above 6: high)
Financial health
Current ratio Q 11.13 (at or above 1.5: strong)
Debt / equity Q 0.00 (at or below 0.5: strong)
Interest coverage Q (2,374.71)
Growth
Revenue growth Q +466.40% (above 0%: growing)
Operating income growth Q −59.13% (below 0%: shrinking)
EPS, this year −6.98% (below 0%: weak)
EPS, next year A −29.95% (below 0%: weak)
Revenue, next year A +153.53% (at or above 10%: strong)
EPS, past 5 yrs —
EPS, next 5 yrs A −15.07% (below 0%: weak)

Green and red mark values outside typical ranges; (Q) is the latest quarter, (A) analysts’ estimates. How we judge →

Valuation vs history

P/S against its own 10 years 88.85%
10-year low 10-year high
P/B against its own 10 years 93.87%
10-year low 10-year high
EV/Sales against its own 10 years 88.98%
10-year low 10-year high

Dividends

Yield
—
Annual rate
—
Payout ratio
—

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 375 489 848 971
Receivables 15 — — —
Inventory — — — —
Other 4 1 — —
405 510 871 999
2023 2024 2025 Q'26
Payables 7 6 4 12
ST’ Debt — — — —
Other 1 0 0 1
86 68 83 90

Compound Annual Growth %

10y 5y 3y
Sales — 2.87% (5.74%)
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — 40.96% 47.71%

Earnings Trends EPS, adjusted, against the consensus

EPS $

Mar Jun Sep Dec Year
’26 (0.71) (0.62) (1.32) — —
’25 (0.82) (0.95) (0.94) (0.97) (3.69)
’24 (0.69) (0.58) (0.82) (0.88) (2.98)
’23 (0.70) (0.67) (0.90) (0.25) (2.52)
’22 (0.71) (0.78) (0.79) (0.60) (2.87)
’21 (0.29) (0.55) (0.56) (0.66) (2.09)
’20 (5.60) (6.98) (0.39) (0.29) (3.15)
Fiscal quarters ending in the months shown.

Revenue $m

Mar Jun Sep Dec Year
’26 34 65 — — —
’25 22 11 3 3 39
’24 10 26 4 7 47
’23 9 17 5 48 79
’22 10 12 10 16 47
’21 19 19 20 15 73
’20 3 3 15 13 34
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (89) (54) (78) — —
’25 (79) (60) (27) (67) (233)
’24 (40) (43) (50) (62) (195)
’23 (44) (35) (32) 8 (103)
’22 (40) (39) (34) (40) (153)
’21 (23) (31) (37) (38) (129)
’20 (12) (11) 132 (20) 88
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (89) (55) (78) — —
’25 (80) (61) (27) (67) (234)
’24 (47) (48) (50) (63) (207)
’23 (48) (46) (40) (4) (137)
’22 (41) (40) (36) (40) (156)
’21 (23) (31) (38) (39) (131)
’20 (13) (15) 129 (22) 79
Fiscal quarters ending in the months shown.

Valuation

The price implies free cash flow after share-based pay growing 82.7% a year for ten years.

Implied
82.7%
Open the model

Target Price Range

Analyst price targets

Recommendation Rating

1.3
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Ten-year view Analyst estimates Powerpack
Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 TTM Sep ’26 Trend 10 yrs 2026e 2027e 2028e Next 3/yr
Income, $m
Income, $m Revenue — — — 3 34 73 47 79 47 39 105 +54.0% 99 49 48 +7.0%
Gross margin, % — — 0.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 +100.0 pt
EBT — — (21) (41) (46) (100) (155) (147) (224) (311) (349) +46.5%
EBT margin, % — — 0.00 (1,405.79) (133.96) (137.60) (330.60) (186.99) (475.57) (794.04) 0.00 (794.0) pt
Net income — 0 (21) (41) (46) (100) (155) (147) (224) (311) (349) n/m
Per share, $
Per share, $ Revenue — — 0.00 1.73 1.96 1.52 0.87 1.35 0.63 0.46 0.00 n/m
Earnings — — (0.48) (24.28) (3.15) (2.09) (2.87) (2.52) (2.98) (3.69) (3.62) +33.8%
Cash flow — — (0.40) 10.54 5.08 (2.69) (2.84) (1.76) (2.59) (2.76) (2.87) +31.7%
Capex — — 0.00 (0.31) (0.52) (0.03) (0.05) (0.59) (0.17) (0.02) (0.01) n/m
Free cash flow — — (0.40) 10.23 4.56 (2.72) (2.89) (2.35) (2.76) (2.77) (2.89) +31.8%
Book value — — 0.88 20.41 16.36 9.58 9.09 6.77 11.14 18.70 16.13 +54.9%
Shares, m — — 45 2 17 48 54 58 75 84 95 +9.6%
Valuation, ×
Valuation, × P/E — — — 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.0
P/S — — — 0.00 31.61 41.83 28.61 18.83 64.14 167.66 119.82 50.4
P/B — — — 0.00 3.79 6.63 2.73 3.75 3.61 4.16 7.79 3.5
EV/Sales — — — 0.00 22.92 35.77 19.94 14.07 53.80 146.07 110.58 41.8
EV/FCF — — — 2.13 9.87 (19.96) (5.99) (8.05) (12.21) (24.44) (40.19) (8.4)
Cash, $m
Cash, $m Operating cash flow — — (18) 18 88 (129) (153) (103) (195) (233) (288) +44.3%
Capex — — (1) (1) (9) (2) (3) (34) (13) (1) (1) +1.0%
Free cash flow — — (18) 17 79 (131) (156) (137) (207) (234) (289) +44.4%
Balance, $m
Balance, $m Working capital — — 37 58 192 359 348 320 443 788 909 +54.7%
Net debt — — (41) (91) (296) (441) (406) (374) (487) (847) (971) +54.4%
Shareholders’ equity — — 39 35 284 460 490 395 836 1,580 1,615 +69.7%
Returns, %
Returns, % ROA — — (97.07) (51.26) (18.10) (18.34) (25.61) (24.93) (28.81) (22.89) (24.36) +74.2 pt
ROIC — — 0.00 0.00 0.00 (342.22) (119.65) (483.64) (46.84) (29.80) (39.30) (29.8) pt
ROE — — 39.45 75.79 (52.17) (26.96) (32.60) (33.21) (36.38) (25.78) (27.29) (65.2) pt
People
People Employees — — — 55 75 141 167 187 188 238 — +27.7%
Revenue/emp, $m — — — 0.05 0.45 0.52 0.28 0.42 0.25 0.16 — +20.7%
Negative figures in brackets.
estimates

All 10 years →

Fiscal years to Dec 2025 · latest quarter Jun 2026 · fundamentals updated 2 Nov 2026

Business profile

Updated

Kymera Therapeutics is a clinical-stage biotechnology company developing oral medicines, primarily for immune and inflammatory diseases. It has no products on the market and has not generated revenue from product sales. Its headquarters are in Watertown, and founder Nello Mainolfi is its chief executive officer.

Kymera’s central approach is targeted protein degradation. Rather than only blocking a protein’s activity, its small-molecule candidates are designed to engage the body’s cellular recycling system to remove disease-causing proteins. The company aims to reach targets that existing technologies have not addressed adequately, including proteins involved in inflammation.

Kymera Therapeutics, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
TECH Bio-Techne Corp $11.4B 62.2× 54.2× +1.33% (above 0%: growing) n/m −6.83% (below 0%: shrinking) 65.82% 23.13% Compare
SMMT Summit Therapeutics PLC $11.3B — (loss-making) — (loss-making) −100.00% (below 0%: shrinking) n/m −112.80% (below 0%: shrinking) 0.00% 0.00% Compare
KYMR Kymera Therapeutics, Inc. $10.9B — (loss-making) — (loss-making) +466.40% (above 0%: growing) n/m −186.64% (below 0%: shrinking) 100.00% 0.00%
BMRN BioMarin Pharmaceutical Inc. $10.9B — (loss-making) 32.7× +32.02% (above 0%: growing) n/m −52.25% (below 0%: shrinking) 79.95% (8.01%) Compare
PCVX Vaxcyte, Inc. $9.8B — (loss-making) — — n/m −92.55% (below 0%: shrinking) 0.00% 0.00% Compare
TGTX TG Therapeutics, Inc. $8.9B 19.1× 62.4× +70.27% (above 0%: growing) −73.68% (below 0%: shrinking) +427.05% (above 0%: growing) 82.86% 9.02% Compare
IBRX ImmunityBio, Inc. $8.5B — (loss-making) — (loss-making) +93.91% (above 0%: growing) n/m +13.38% (above 0%: growing) 99.42% (120.41%) Compare
TWST Twist Bioscience Corporation $7.9B — (loss-making) — (loss-making) +23.24% (above 0%: growing) n/m −7.23% (below 0%: shrinking) 52.76% (30.65%) Compare
CAI Caris Life Sciences,�Inc. $7.4B 77.7× 254× +26.99% (above 0%: growing) −40.33% (below 0%: shrinking) −140.21% (below 0%: shrinking) 0.00% 7.01% Compare
Median of peers $9.3B 62.2× 58.3× +26.99% — −29.74% 59.29% 0.00%

All 621 Biotechnology stocks →

Pay and ownership Proxy statement filed 29 April 2026

Chief executive’s pay

Year Total pay Actually paid $100 invested
2025 8.55m 27.85m 125.50
2024 15.43m 19.76m 64.89
2023 9.67m 6.41m 41.06
2022 6.93m (24.97m) 40.26
2021 11.57m 12.61m 102.40

Ownership

Directors and executive officers, together 15.98%
FMR LLC 10.86%
Entities affiliated with Baker Bros. Advisors LP 10.56%
Felix J. Baker, Ph.D. 10.56%
Avoro Capital Advisors LLC 9.07%
Entities affiliated with BVF Partners L.P. 8.33%
Entities affiliated with the Vanguard Group 6.37%
T. Rowe Price Associates, Inc. 6.20%
Entities affiliated with Atlas Venture 5.57%
Wellington Management Group LLP 5.37%
Total pay is as the Summary Compensation Table states it; actually paid revalues the year’s share awards at its end, as the SEC’s pay-versus-performance rule asks. $100 invested is what $100 in the company’s shares at the start of the earliest year shown was worth at each year’s end. Ownership is the proxy’s own table: the directors and officers as a group, and every holder of 5% or more. Read the proxy statement

Kymera Therapeutics, Inc. (KYMR) Latest News

12 Aug

Impact 4 · · The Motley Fool transcript

KYMR metrics, ten years each

stockrow.com/KYMR · Data as of Nov 2, 2026 · For information only; not investment advice. · © 2026 stockrow.com