Ascendis Pharma A/S

ASND Healthcare Biotechnology

Ascendis Pharma A/S’s revenue for fiscal 2025 (year ended December 2025) was $814.8 million, up 107.1% from fiscal 2024. In the quarter to June 2026, revenue grew 119.9%, EPS grew 612.3%, free cash flow grew 2,335.9% and total debt fell 41.8%, each against the same quarter a year earlier. Revenue growth for five consecutive years, operating cash flow growth for three; insiders bought in the last twelve months.

225.78 0.84 −0.37%
Market cap
$14.9B
P/E
16.3×
Fwd P/E
13.0×
Dividend yield
—
F-score
5/9
Altman Z
2.02
Beneish M
−2.51
Dividend safety
n/a

Insider Decisions trades per month

Total buys 0.78
Total sells 5.45
Totals in millions of $.
Dec 25 Mar 26 Jun 26 Sep 26
Buy — — — — — — 3 1 — 1 — —
Sell — — — — — — 1 — — — 1 —
Insider Ownership 0.00%

Capital & Financial Ratios $m

Market Cap 14,880.00
Revenue 1,212.10
Net Income 865.91
Free Cash Flow 387.49
Net Debt (421.11)
Current Ratio 2.99 (at or above 1.5: strong)
Debt/Equity 0.31 (at or below 0.5: strong)
P/E ratio 16.28
Fwd P/E 13.00
P/S ratio 11.99 (above 10: high)
P/B ratio 8.70 (above 6: high)
Past 5Y EPS Growth —
This Y EPS Growth 486.85% (at or above 15%: strong)
Next Y EPS Growth (37.41%) (below 0%: weak)
Next Y revenue growth 68.15% (at or above 10%: strong)
Next 5Y EPS Growth 38.10% (at or above 15%: strong)

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/S against its own 10 years 0.18%
10-year low 10-year high
P/B against its own 10 years 66.76%
10-year low 10-year high
EV/Sales against its own 10 years 0.18%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2023 Powerpack
2022 Powerpack
2021 Powerpack
2020 Powerpack
2019 Powerpack
special payouts not included in total or ratios

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 432 605 697 944
Receivables 60 192 178 261
Inventory 226 320 341 361
Other — — — —
761 1,148 1,255 1,617
2023 2024 2025 Q'26
Payables 102 104 103 121
ST’ Debt 12 532 550 76
Other 81 345 550 329
214 982 1,210 541

Compound Annual Growth %

10y 5y 3y
Sales 56.90% 152.47% 147.23%
Cash Flow 0.00% 0.00% 0.00%
Earnings 0.00% 0.00% 0.00%
Book Value 0.00% 0.00% 0.00%

Revenue $m

Mar Jun Sep Dec Year
’26 289 394 — — —
’25 106 179 250 279 815
’24 104 39 64 187 393
’23 36 52 52 149 289
’22 8 7 15 24 54
’21 1 1 1 6 9
’20 2 2 3 1 8
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (9) 328 — — —
’25 (15) (10) 2 84 61
’24 (110) (65) (65) (91) (331)
’23 (158) (169) (135) (43) (506)
’22 (147) (125) (85) (166) (522)
’21 (98) (139) (110) (147) (494)
’20 (74) (62) (76) (98) (310)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (18) 324 — — —
’25 (16) (14) 2 80 51
’24 (111) (64) (66) (91) (332)
’23 (159) (170) (136) (43) (508)
’22 (147) (123) (88) (170) (527)
’21 (116) (131) (123) (153) (523)
’20 (80) (68) (78) (103) (329)
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 11.41 3.29 — — —
’25 (1.66) (0.69) (1.17) (0.64) (4.25)
’24 (2.48) (2.05) (1.89) (0.68) (7.07)
’23 (2.12) (2.35) (3.12) (1.66) (9.24)
’22 (2.48) (1.54) (3.05) (3.78) (10.96)
’21 (1.41) (3.01) (1.73) (2.14) (8.28)
’20 (1.46) (2.17) (2.70) (3.15) (9.46)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1.1
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low 11.92 19.60 38.28 59.58 92.00 109.36 61.58 64.33 111.09 118.03

Analyst estimates 2026–2028

Powerpack
High 21.79 42.00 76.99 140.15 183.98 178.71 137.40 129.43 161.00 229.94
People
People Employees 101 137 216 330 482 639 797 879 1,017 1,189
Revenue/emp, $m 0.05 0.01 0.06 0.05 0.02 0.01 0.07 0.33 0.39 0.69
Income, $m
Income, $m Revenue 5 2 12 15 8 9 54 289 393 815
Gross margin, % 100.00 100.00 100.00 100.00 100.00 54.71 76.28 83.36 87.83 86.82
EBT (76) (141) (154) (244) (479) (454) (609) (513) (404) (241)
EBT margin, % (1,492.23) (8,128.83) (1,233.25) (1,631.78) (6,028.69) (4,936.26) (1,129.12) (177.77) (102.64) (29.53)
Net income (76) (140) (154) (244) (479) (454) (614) (521) (409) (258)
Depreciation 1 1 1 7 11 18 19 20 19 20
Per share, $
Per share, $ Revenue 0.19 0.05 0.30 0.32 0.16 0.17 0.96 5.13 6.80 13.44
Earnings (2.85) (4.33) (3.74) (5.25) (9.46) (8.28) (10.96) (9.24) (7.07) (4.25)
Cash flow (2.51) (3.20) (3.99) (4.24) (6.13) (9.02) (9.31) (8.99) (5.72) 1.01
Capex (0.03) (0.03) (0.08) (0.12) (0.37) (0.52) (0.09) (0.05) (0.01) (0.16)
Free cash flow (2.53) (3.23) (4.07) (4.36) (6.50) (9.54) (9.41) (9.03) (5.73) 0.85
Book value 7.36 6.29 8.05 14.38 18.93 19.09 4.95 (2.80) (1.98) (3.04)
Shares, m 27 34 41 47 51 55 56 56 58 61
Valuation, ×
Valuation, × P/E 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
P/S 103.77 773.87 205.98 431.91 1,062.89 800.73 125.55 24.87 20.25 15.86
P/B 2.71 6.32 7.78 9.67 8.81 7.05 24.40 0.00 0.00 0.00
EV/Sales 64.62 646.19 179.72 389.93 973.61 725.97 121.11 25.41 21.07 16.22
EV/FCF (4.89) (10.29) (13.44) (28.80) (23.50) (12.78) (12.38) (14.43) (24.99) 257.17
Cash, $m
Cash, $m Operating cash flow (67) (107) (164) (197) (310) (494) (522) (506) (331) 61
Capex (1) (1) (3) (6) (19) (29) (5) (3) (1) (10)
Free cash flow (67) (109) (167) (203) (329) (523) (527) (508) (332) 51
Balance, $m
Balance, $m Working capital 189 204 300 631 785 835 793 547 166 45
Total debt — — — 41 112 119 536 590 927 986
Net debt (200) (221) (328) (629) (709) (688) (239) 158 321 289
Shareholders’ equity 195 212 331 669 958 1,045 277 (158) (114) (184)
Returns, %
Returns, % ROA (42.51) (62.41) (49.95) (43.04) (50.99) (37.77) (50.54) (51.04) (37.71) (18.76)
ROIC 0.00 0.00 (4,420.67) (397.86) (94.80) (93.45) (968.11) (84,748.35) (91.04) (91.65)
ROE (46.08) (68.81) (56.66) (48.86) (58.84) (45.30) (92.90) (870.08) 300.75 172.80
Negative figures in brackets.

All 10 years →

Fiscal years to Dec 2025 · latest quarter Jun 2026

Charts ten years each

Ascendis Pharma A/S vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
EXEL Exelixis, Inc. $15.6B 18.8× 16.7× +10.63% (above 0%: growing) +25.00% (above 0%: growing) +557.25% (above 0%: growing) 96.71% 39.51% Compare
ASND Ascendis Pharma A/S $14.9B 16.3× 13.0× +119.88% (above 0%: growing) n/m +2,335.93% (above 0%: growing) 91.85% 64.98%
JAZZ Jazz Pharmaceuticals PLC $13.9B 13.8× 17.3× +15.55% (above 0%: growing) n/m +140.99% (above 0%: growing) 90.37% 20.54% Compare
HALO Halozyme Therapeutics, Inc. $13.8B 34.6× 10.6× +47.67% (above 0%: growing) +44.12% (above 0%: growing) +141.18% (above 0%: growing) 83.54% 59.80% Compare
BBIO BridgeBio Pharma, Inc. $13.1B — (loss-making) — (loss-making) +120.39% (above 0%: growing) n/m +16.59% (above 0%: growing) 93.83% (43.94%) Compare
CORT Corcept Therapeutics Incorporated $12.3B 212× 139× +31.74% (above 0%: growing) +21.21% (above 0%: growing) −29.89% (below 0%: shrinking) 98.41% 16.12% Compare
SMMT Summit Therapeutics PLC $12.3B — (loss-making) — (loss-making) −100.00% (below 0%: shrinking) n/m −112.80% (below 0%: shrinking) 0.00% 0.00% Compare
TECH Bio-Techne Corp $11.4B 62.0× 37.6× +1.33% (above 0%: growing) n/m −6.83% (below 0%: shrinking) 65.82% 23.13% Compare
BMRN BioMarin Pharmaceutical Inc. $10.9B 144× 16.1× +19.91% (above 0%: growing) −81.60% (below 0%: shrinking) −20.28% (below 0%: shrinking) 79.51% 11.21% Compare
Median of peers $12.7B 48.3× 17.0× +17.73% +23.11% +4.88% 86.96% 18.33%

All 614 Biotechnology stocks →

Ascendis Pharma A/S (ASND) key facts

  • Concern: Ascendis Pharma A/S reported a net loss of $258.0 million, or a loss of $4.25 per share, for fiscal 2025.
  • Strength: Ascendis Pharma A/S’s revenue for fiscal 2025 (year ended December 2025) was $814.8 million, up 107.1% from fiscal 2024.
  • Ascendis Pharma A/S (ASND) is a Biotechnology company in the Healthcare sector, traded in the US as an ADR.
  • As of October 16, 2026, ASND traded at $225.78, a market capitalization of $14.9 billion.
  • At that price the stock trades at 16.3× trailing-twelve-month earnings and 12.0× sales.
  • Return on equity was 172.8% and debt-to-equity 0.31.
  • Its Piotroski F-score is 5 out of 9 and its Altman Z-score is 2.02 (grey zone) for fiscal 2025.

Source: company filings (standardised) and stockrow calculations.

Ascendis Pharma A/S (ASND) Latest News

stockrow.com/ASND · Data as of Jun 30, 2026 · For information only; not investment advice. · © 2026 stockrow.com