Praxis Precision Medicines, Inc.

PRAX Healthcare Biotechnology

Praxis Precision Medicines, Inc.’s revenue for fiscal 2024 (year ended December 2024) was $8.6 million, up 249.5% from fiscal 2023. In the quarter to June 2026, revenue grew 1,349.1%, EPS grew 13.3% and free cash flow fell 43.5%, each against the same quarter a year earlier.

241.76 6.48 −2.61%
Market cap
$6.9B
P/E
0.0×
Fwd P/E
−24.3×
Dividend yield
—
F-score
n/a
Altman Z
19.09
Beneish M
n/a
Dividend safety
n/a

Insider Decisions trades per month

Total sells 11.08
Totals in millions of $.
Dec 25 Mar 26 Jun 26 Sep 26
Buy — — — — — — — — — — — —
Sell 2 — — — — — — 1 — — — —
Insider Ownership 9.86%

Capital & Financial Ratios $m

Market Cap 6,930.00
Revenue 8.55
Net Income (339.13)
Free Cash Flow (306.16)
Net Debt (758.55)
Current Ratio 15.73 (at or above 1.5: strong)
Debt/Equity 0.00 (at or below 0.5: strong)
P/E ratio 0.00
Fwd P/E (24.30) (negative: loss-making)
P/S ratio 823.42 (above 10: high)
P/B ratio 5.25
Past 5Y EPS Growth —
This Y EPS Growth (1.74%) (below 0%: weak)
Next Y EPS Growth 26.89% (at or above 15%: strong)
Next Y revenue growth (97.21%) (below 0%: weak)
Next 5Y EPS Growth 16.47% (at or above 15%: strong)

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/B against its own 10 years 82.68%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2025 Powerpack
2024 Powerpack
2023 Powerpack
2022 Powerpack
2021 Powerpack
predictions special payouts not included in total or ratios

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 81 393 599 759
Receivables — — — —
Inventory — — — —
Other — — — —
85 404 611 772
2023 2024 2025 Q'26
Payables 6 13 25 23
ST’ Debt — — — —
Other — — — —
16 38 60 49

Compound Annual Growth %

10y 5y 3y
Sales — — —
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — 25.03% 125.97%

Revenue $m

Mar Jun Sep Dec Year
’26 — — — — —
’24 0 0 0 7 9
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (86) (78) — — —
’25 (53) (55) (65) (76) (249)
’24 (21) (27) (27) (56) (132)
’23 (33) (31) (23) (24) (111)
’22 (54) (57) (45) (29) (185)
’21 (26) (30) (24) (45) (125)
’20 (9) (10) (14) (20) (53)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (86) (79) — — —
’25 (53) (55) (65) (76) (249)
’24 (21) (27) (27) (56) (132)
’23 (33) (31) (23) (24) (111)
’22 (54) (57) (45) (29) (185)
’21 (26) (30) (24) (45) (126)
’20 (9) (10) (14) (20) (53)
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 (3.20) (2.87) — — —
’25 (3.29) (3.31) (3.36) (3.50) (13.48)
’24 (2.84) (1.74) (2.75) (2.94) (10.21)
’23 (10.64) (7.35) (2.70) (2.97) (18.69)
’22 (22.64) (19.79) (14.39) (13.04) (69.56)
’21 (10.64) (13.19) (14.99) (19.49) (59.07)
’20 (76.67) (105.62) (181.41) (13.04) (117.84)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1.3
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low — — — — 358.50 190.65 22.20 11.85 20.50 26.70

Analyst estimates 2026–2028

Powerpack
High — — — — 877.35 914.27 309.00 78.75 86.93 317.72
People
People Employees — — — 37 67 139 109 82 116 168
Revenue/emp, $m — — — 0.00 0.00 0.00 0.00 0.03 0.07 0.00
Income, $m
Income, $m Revenue — — — — — — — 2 9 —
Gross margin, % — — 0.00 0.00 0.00 0.00 0.00 100.00 100.00 —
EBT — — (26) (36) (62) (167) (214) (123) (183) (303)
EBT margin, % — — 0.00 0.00 0.00 0.00 0.00 (5,037.88) (2,137.48) 0.00
Net income — 0 (27) (36) (62) (167) (214) (123) (183) (303)
Depreciation — — 0 0 0 2 1 0 (5) (3)
Per share, $
Per share, $ Revenue — — 0.00 0.00 0.00 0.00 0.00 0.37 0.48 0.00
Earnings — — (306.49) (347.98) (117.84) (59.07) (69.56) (18.69) (10.21) (13.48)
Cash flow — — (239.27) (327.33) (88.15) (43.99) (60.22) (16.85) (7.36) (11.07)
Capex — — (0.73) (1.01) 0.00 (0.37) (0.14) (0.01) 0.00 0.00
Free cash flow — — (240.00) (328.33) (88.15) (44.36) (60.36) (16.86) (7.36) (11.07)
Book value — — (473.88) (793.42) 481.50 88.57 24.77 10.57 24.88 39.02
Shares, m — — 0 0 1 3 3 7 18 23
Valuation, ×
Valuation, × P/E — — — — — — — 0.00 0.00 —
P/S — — — — — — — 56.32 161.13 —
P/B — — — — — — — 1.98 3.09 —
EV/Sales — — — — — — — 23.10 115.23 —
EV/FCF — — — — — — — (0.51) (7.47) —
Cash, $m
Cash, $m Operating cash flow — — (21) (33) (53) (125) (185) (111) (132) (249)
Capex — — 0 0 — (1) 0 0 — 0
Free cash flow — — (21) (34) (53) (126) (185) (111) (132) (249)
Balance, $m
Balance, $m Working capital — — 14 39 287 249 76 69 367 551
Total debt — — — 1 1 4 4 — — —
Net debt — — (18) (45) (297) (276) (100) (81) (393) (599)
Shareholders’ equity — — (41) (81) 287 251 76 70 445 878
Returns, %
Returns, % ROA — — (294.75) (120.50) (40.08) (56.07) (104.95) (121.41) (64.03) (42.68)
ROIC — — 0.00 0.00 0.00 0.00 0.00 0.00 (236.57) (73.12)
ROE — — 47.89 66.67 (68.13) (62.07) (130.94) (169.13) (70.98) (45.83)
Negative figures in brackets.

All 10 years →

Fiscal years to Dec 2024 · latest quarter Dec 2024

Charts ten years each

Praxis Precision Medicines, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
ARWR Arrowhead Pharmaceuticals, Inc. $8.3B — (loss-making) — (loss-making) +171.02% (above 0%: growing) n/m −15.43% (below 0%: shrinking) 100.00% (226.03%) Compare
ABVX Abivax SA Sponsored ADR $8.1B — (loss-making) — — n/m −48.28% (below 0%: shrinking) 0.00% 0.00% Compare
SYRE Spyre Therapeutics, Inc. $7.4B — (loss-making) — (loss-making) −100.00% (below 0%: shrinking) n/m −50.07% (below 0%: shrinking) 0.00% 0.00% Compare
IONS Ionis Pharmaceuticals, Inc. $7.3B — (loss-making) — (loss-making) −40.73% (below 0%: shrinking) n/m +299.29% (above 0%: growing) 98.98% (38.18%) Compare
PRAX Praxis Precision Medicines, Inc. $6.9B — (loss-making) — (loss-making) +1,349.13% (above 0%: growing) n/m −43.54% (below 0%: shrinking) 100.00% 0.00%
IOVA Iovance Biotherapeutics, Inc. $6.7B — (loss-making) — (loss-making) +65.65% (above 0%: growing) n/m +11.52% (above 0%: growing) 56.10% (52.26%) Compare
BLTE Belite Bio, Inc. Sponsored ADR $6.2B — (loss-making) — — n/m +64.67% (above 0%: growing) — 0.00% Compare
RYTM Rhythm Pharmaceuticals, Inc. $6.1B — (loss-making) — (loss-making) +46.91% (above 0%: growing) n/m +60.74% (above 0%: growing) 87.47% (68.14%) Compare
LGND Ligand Pharmaceuticals Incorporated $6.0B 29.5× 54.7× +33.73% (above 0%: growing) +868.00% (above 0%: growing) +35.53% (above 0%: growing) 94.95% 13.49% Compare
Median of peers $7.0B — — +40.32% — +23.53% 87.47% (19.09%)

All 614 Biotechnology stocks →

Praxis Precision Medicines, Inc. (PRAX) key facts

  • Strength: Praxis Precision Medicines, Inc.’s revenue for fiscal 2024 (year ended December 2024) was $8.6 million, up 249.5% from fiscal 2023.
  • Praxis Precision Medicines, Inc. (PRAX) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • As of October 16, 2026, PRAX traded at $241.76, a market capitalization of $6.9 billion.
  • Return on equity was −45.8% and debt-to-equity 0.00.
  • Its Altman Z-score is 19.09 (safe zone) for fiscal 2024.

Source: company filings (standardised) and stockrow calculations.

Praxis Precision Medicines, Inc. (PRAX) Latest News

13 Aug

Impact 3 · transcript

12 May

Impact 4 · transcript
stockrow.com/PRAX · Data as of Dec 31, 2024 · For information only; not investment advice. · © 2026 stockrow.com