Arrowhead Pharmaceuticals, Inc. (ARWR) vs Praxis Precision Medicines, Inc. (PRAX)

Arrowhead Pharmaceuticals, Inc. and Praxis Precision Medicines, Inc. are both Biotechnology companies. Arrowhead Pharmaceuticals, Inc. is the larger, with a market value of $8.3B against $6.9B — 1.2× the size. Praxis Precision Medicines, Inc. grew revenue faster over the last twelve months: 249.5% against 16.1%. Praxis Precision Medicines, Inc. has the higher net margin (0.00% vs −47.8%) and the lower return on invested capital (−40.6% vs 0.00%). Across the 16 metrics below, Arrowhead Pharmaceuticals, Inc. leads on 8 and Praxis Precision Medicines, Inc. on 8.

Valuation

Metric ARWR PRAX Biotechnology median
P/E n/m n/m 8.50
P/S 11.97 823.42 9.71
P/B 17.20 5.25 2.13
Price to free cash flow n/m n/m 20.82
EV/EBITDA n/m n/m 0.64
EV/Sales 10.87 734.73 9.21
Earnings yield (4.03%) (5.35%) (33.15%)
Free cash flow yield (0.94%) (4.35%) (25.50%)

Profitability

Metric ARWR PRAX Biotechnology median
Gross margin 100.00% 100.00% 65.16%
Operating margin (33.82%) 0.00% 0.00%
Net margin (47.79%) 0.00% 0.00%
Free cash flow margin (11.22%) 0.00% 0.00%
Return on equity (64.91%) (38.86%) (56.36%)
Return on assets (18.32%) (36.80%) (48.04%)
Return on invested capital 0.00% (40.58%) 0.00%

Growth

Metric ARWR PRAX Biotechnology median
Revenue growth (TTM) 16.13% 249.53% 6.02%
EPS growth (last fiscal year) 99.80% (32.03%) 30.26%
Revenue growth, 5-year CAGR 56.63% — 9.41%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric ARWR PRAX Biotechnology median
Debt to equity 1.85 0.00 0.00
Current ratio 5.90 15.73 4.72
Net debt to EBITDA (5.70) 1.82 0.96

Dividend

Metric ARWR PRAX Biotechnology median
Dividend yield — — 0.09%
Payout ratio — — —

Size

Metric ARWR PRAX Biotechnology median
Market cap 8.26b 6.93b 135.18m

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