Arrowhead Pharmaceuticals, Inc.

ARWR Healthcare Biotechnology

Arrowhead Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended September 2025) was $829.4 million, up 23,258.2% from fiscal 2024. In the quarter to June 2026, revenue grew 171.0%, EPS fell 7.94%, free cash flow fell 15.4% and total debt rose 259.5%, each against the same quarter a year earlier.

55.90 2.60 −4.44%
Market cap
$8.3B
P/E
0.0×
Fwd P/E
−23.1×
Dividend yield
—
F-score
5/9
Altman Z
2.98
Beneish M
n/a
Dividend safety
n/a

Insider Decisions trades per month

Total sells 37.34
Totals in millions of $.
Dec 25 Mar 26 Jun 26 Sep 26
Buy — — — — — — — — — — — —
Sell 1 9 3 — 1 2 1 — — 2 — —
Insider Ownership 7.26%

Capital & Financial Ratios $m

Market Cap 8,260.00
Revenue 669.50
Net Income (272.13)
Free Cash Flow (75.11)
Net Debt (737.89)
Current Ratio 5.90 (at or above 1.5: strong)
Debt/Equity 1.85
P/E ratio 0.00
Fwd P/E (23.10) (negative: loss-making)
P/S ratio 11.97 (above 10: high)
P/B ratio 17.20 (above 6: high)
Past 5Y EPS Growth —
This Y EPS Growth (35,135.10%) (below 0%: weak)
Next Y EPS Growth (37.82%) (below 0%: weak)
Next Y revenue growth (44.34%) (below 0%: weak)
Next 5Y EPS Growth 11.96%

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/S against its own 10 years 20.20%
10-year low 10-year high
P/B against its own 10 years 85.33%
10-year low 10-year high
EV/Sales against its own 10 years 22.38%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2025 Powerpack
2024 Powerpack
2023 Powerpack
2022 Powerpack
2021 Powerpack
2020 Powerpack
2017 Powerpack
predictions special payouts not included in total or ratios

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 404 681 919 1,602
Receivables — — 7 9
Inventory — — — —
Other 4 5 14 36
416 695 951 1,671
2023 2024 2025 Q'26
Payables 36 11 18 28
ST’ Debt 11 — 40 40
Other 0 0 11 6
105 103 195 283

Compound Annual Growth %

10y 5y 3y
Sales 115.61% 56.63% 50.52%
Cash Flow 0.00% 0.00% 0.00%
Earnings 0.00% 0.00% 0.00%
Book Value 16.47% 1.74% 6.37%

Revenue $m

Dec Mar Jun Sep Year
’26 264 74 75 — —
’25 3 543 28 256 829
’24 4 — — — 4
’23 63 146 16 16 241
’22 27 152 32 32 243
’21 21 33 46 38 138
’20 29 24 27 8 88
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Dec Mar Jun Sep Year
’26 13 84 (177) — —
’25 (146) 460 (155) 20 180
’24 (118) (92) (115) (137) (463)
’23 (76) (32) (21) (26) (154)
’22 (61) 63 (69) (69) (136)
’21 (39) 264 (30) (24) 171
’20 (24) (28) (33) (11) (96)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Dec Mar Jun Sep Year
’26 11 82 (181) — —
’25 (154) 455 (157) 13 157
’24 (186) (126) (130) (162) (604)
’23 (114) (59) (67) (90) (331)
’22 (67) 58 (78) (101) (189)
’21 (43) 257 (34) (32) 148
’20 (28) (31) (36) (13) (108)
Fiscal quarters ending in the months shown.

EPS $

Dec Mar Jun Sep Year
’26 0.22 (0.93) (1.36) — —
’25 (1.39) 2.75 (1.26) (0.18) (0.01)
’24 (1.24) (1.02) (1.38) (1.38) (5.00)
’23 (0.39) 0.45 (0.96) (1.03) (1.92)
’22 (0.60) 0.41 (0.68) (0.81) (1.67)
’21 (0.20) (0.26) (0.29) (0.61) (1.36)
’20 (0.03) (0.20) (0.13) (0.48) (0.84)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1.1
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to September

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low 1.20 1.42 3.57 11.67 19.51 57.92 26.81 20.67 17.05 9.57

Analyst estimates 2026–2028

Powerpack
High 8.22 4.54 22.39 73.72 86.75 93.66 70.09 42.48 39.83 72.36
People
People Employees 94 93 95 109 232 329 397 525 609 711
Revenue/emp, $m 0.00 0.34 0.17 1.55 0.38 0.42 0.61 0.46 0.01 1.17
Income, $m
Income, $m Revenue 0 31 16 169 88 138 243 241 4 829
Gross margin, % 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00
EBT (82) (34) (54) 68 (85) (141) (173) (206) (612) 52
EBT margin, % (51,623.88) (109.46) (337.30) 40.37 (96.09) (101.85) (71.01) (85.78) (17,247.54) 6.21
Net income (82) (34) (54) 68 (85) (141) (176) (209) (610) 30
Depreciation 3 5 5 6 6 9 13 10 15 18
Per share, $
Per share, $ Revenue 0.00 0.43 0.19 1.80 0.87 1.33 2.31 2.26 0.03 6.20
Earnings (1.34) (0.47) (0.65) 0.69 (0.84) (1.36) (1.67) (1.92) (5.00) (0.01)
Cash flow (1.06) (0.32) (0.56) 1.84 (0.95) 1.65 (1.29) (1.44) (3.86) 1.34
Capex (0.06) (0.11) (0.02) (0.13) (0.12) (0.23) (0.50) (1.66) (1.18) (0.17)
Free cash flow (1.12) (0.43) (0.58) 1.72 (1.07) 1.42 (1.79) (3.10) (5.05) 1.17
Book value 1.56 1.09 1.14 2.60 4.58 3.94 3.97 2.69 1.60 3.76
Shares, m 61 74 84 94 101 104 105 107 120 134
Valuation, ×
Valuation, × P/E 0.00 0.00 0.00 40.84 0.00 0.00 0.00 0.00 0.00 0.00
P/S 2,831.07 10.47 99.53 15.67 49.29 46.84 14.33 11.64 12.77 5.56
P/B 4.72 4.07 16.87 10.84 9.39 15.84 8.33 9.76 12.14 9.16
EV/Sales 2,308.47 8.46 94.92 14.15 45.94 44.36 13.11 11.56 11.24 4.76
EV/FCF (5.36) (8.34) (31.50) 14.83 (37.52) 41.52 (16.88) (8.41) (3.38) 25.17
Cash, $m
Cash, $m Operating cash flow (64) (24) (47) 173 (96) 171 (136) (154) (463) 180
Capex (4) (8) (1) (12) (12) (24) (53) (177) (141) (23)
Free cash flow (68) (32) (49) 161 (108) 148 (189) (331) (604) 157
Balance, $m
Balance, $m Working capital 65 49 66 168 282 238 266 311 592 755
Total debt 3 3 2 — 21 26 82 383 393 255
Net debt (83) (63) (74) (259) (294) (342) (295) (20) (288) (664)
Shareholders’ equity 95 81 95 244 462 409 418 287 191 503
Returns, %
Returns, % ROA (62.76) (29.61) (50.50) 29.46 (19.39) (22.85) (25.11) (28.17) (62.93) (0.13)
ROIC (412.49) (129.96) (166.22) 0.00 (34.78) (139.91) (90.32) (47.98) 0.00 0.00
ROE (79.87) (39.09) (61.84) 40.07 (23.96) (32.36) (42.57) (58.19) (250.72) (0.47)
Negative figures in brackets.

All 10 years →

Fiscal years to Sep 2025 · latest quarter Jun 2026

Charts ten years each

Arrowhead Pharmaceuticals, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
KYMR Kymera Therapeutics, Inc. $9.0B — (loss-making) — (loss-making) +466.40% (above 0%: growing) n/m +9.97% (above 0%: growing) 100.00% (116.32%) Compare
CAI Caris Life Sciences,�Inc. $9.0B 81.3× 163× +45.38% (above 0%: growing) n/m +8.47% (above 0%: growing) 68.10% 10.21% Compare
CYTK Cytokinetics, Incorporated $8.9B — (loss-making) — (loss-making) −57.13% (below 0%: shrinking) n/m −24.02% (below 0%: shrinking) 80.46% (625.95%) Compare
PTGX Protagonist Therapeutics, Inc. $8.8B 106× 25.0× +3,749.17% (above 0%: growing) n/m +839.65% (above 0%: growing) 100.00% 74.37% Compare
TGTX TG Therapeutics, Inc. $8.6B 17.8× 29.4× +70.27% (above 0%: growing) −73.68% (below 0%: shrinking) +427.05% (above 0%: growing) 82.86% 9.02% Compare
AXSM Axsome Therapeutics, Inc. $8.5B — (loss-making) — (loss-making) +45.54% (above 0%: growing) n/m −2.98% (below 0%: shrinking) 93.79% (22.73%) Compare
ARWR Arrowhead Pharmaceuticals, Inc. $8.3B — (loss-making) — (loss-making) +171.02% (above 0%: growing) n/m −15.43% (below 0%: shrinking) 100.00% (226.03%)
ABVX Abivax SA Sponsored ADR $8.1B — (loss-making) — — n/m −48.28% (below 0%: shrinking) 0.00% 0.00% Compare
SYRE Spyre Therapeutics, Inc. $7.4B — (loss-making) — (loss-making) −100.00% (below 0%: shrinking) n/m −50.07% (below 0%: shrinking) 0.00% 0.00% Compare
Median of peers $8.7B 81.3× 29.4× +45.54% — +2.75% 81.66% 0.00%

All 614 Biotechnology stocks →

Arrowhead Pharmaceuticals, Inc. (ARWR) key facts

  • Strength: Arrowhead Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended September 2025) was $829.4 million, up 23,258.2% from fiscal 2024.
  • Arrowhead Pharmaceuticals, Inc. (ARWR) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • As of October 16, 2026, ARWR traded at $55.90, a market capitalization of $8.3 billion.
  • Return on equity was −0.47% and debt-to-equity 1.85.
  • Its Piotroski F-score is 5 out of 9 and its Altman Z-score is 2.98 (grey zone) for fiscal 2025.

Source: company filings (standardised) and stockrow calculations.

Arrowhead Pharmaceuticals, Inc. (ARWR) Latest News

4 Aug

stockrow.com/ARWR · Data as of Jun 30, 2026 · For information only; not investment advice. · © 2026 stockrow.com