Iovance Biotherapeutics, Inc. IOVA
- Market cap
- $4.9B
- P/E
- 0.0×
Follow IOVA
Target Price Range
Analyst price targets
Free account| 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | 2026 | 2027 | 2028 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 4.24 | 4.45 | 7.26 | 8.26 | 18.70 | 15.88 | 5.42 | 3.21 | 7.05 | 1.64 |
Analyst estimates 2026–2028 Powerpack |
Low Price
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| 9.58 | 9.54 | 19.90 | 29.68 | 52.43 | 54.21 | 19.66 | 9.36 | 18.33 | 8.15 |
High Price
|
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| 51 | 63 | 88 | 148 | 241 | 319 | 503 | 557 | 838 | 975 |
Employees
|
|||
| 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Revenue/Emp
|
|||
| — | — | — | — | — | — | — | 1 | 164 | 264 |
Revenue
|
|||
| — | — | — | — | — | — | — | 13.12% | 43.17% | 34.28% |
Gross Margin
|
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| (53) | (92) | (124) | (198) | (260) | (342) | (396) | (448) | (375) | (393) |
EBT
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| 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | (37,638.02%) | (228.56%) | (149.16%) |
EBT Margin
|
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| (53) | (92) | (124) | (198) | (260) | (342) | (396) | (444) | (372) | (391) |
Net Income
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| 1 | 1 | 0 | (2) | 3 | 20 | 22 | 30 | 38 | 40 |
Depreciation
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| 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.01 | 0.57 | 0.74 |
Revenue/Sh
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| (1.85) | (1.41) | (1.27) | (1.59) | (1.88) | (2.23) | (2.49) | (1.89) | (1.28) | (1.09) |
Earnings/Sh
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| (0.59) | (1.21) | (1.04) | (1.28) | (1.48) | (1.49) | (1.84) | (1.54) | (1.22) | (0.85) |
Cash Flow/Sh
|
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| (0.03) | (0.02) | (0.01) | (0.06) | (0.34) | (0.24) | (0.13) | (0.09) | (0.04) | (0.09) |
Capex/Sh
|
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| (0.62) | (1.22) | (1.05) | (1.33) | (1.82) | (1.73) | (1.97) | (1.63) | (1.26) | (0.94) |
Free CF/Sh
|
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| 3.02 | 2.23 | 4.79 | 2.40 | 4.75 | 4.05 | 3.14 | 2.49 | 2.45 | 1.95 |
Book Value/Sh
|
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| 55 | 65 | 97 | 124 | 138 | 153 | 159 | 235 | 290 | 357 |
Shares
|
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| — | — | — | — | — | — | — | 0.00 | 0.00 | 0.00 |
PE Ratio
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|||
| — | — | — | — | — | — | — | 0.00 | 13.07 | 3.70 |
PS Ratio
|
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| — | — | — | — | — | — | — | 3.26 | 3.02 | 1.40 |
PB Ratio
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| — | — | — | — | — | — | — | 0.00 | 11.11 | 2.58 |
EV/Sales
|
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| — | — | — | — | — | — | — | (4.23) | (5.01) | (2.02) |
EV/FCF
|
|||
| (33) | (79) | (101) | (159) | (205) | (228) | (293) | (362) | (353) | (302) |
Op' Cash Flow
|
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| (2) | (1) | (1) | (7) | (47) | (38) | (20) | (22) | (11) | (34) |
Capex
|
|||
| (34) | (80) | (102) | (166) | (252) | (266) | (313) | (384) | (364) | (336) |
FCF
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| 165 | 140 | 461 | 277 | 581 | 419 | 388 | 198 | 335 | 304 |
Working Cap'
|
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| — | — | — | 4 | — | 1 | 1 | 1 | 1 | — |
Total Debt
|
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| (166) | (145) | (469) | (303) | (629) | (503) | (471) | (279) | (323) | (297) |
Net Debt
|
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| 167 | 145 | 466 | 299 | 656 | 622 | 500 | 585 | 710 | 699 |
Sh' Equity
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| (73.75%) | (56.26%) | (38.85%) | (47.86%) | (46.64%) | (44.28%) | (54.93%) | (61.49%) | (44.02%) | (42.88%) |
ROA
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| (7,483.12%) | (53,748.26%) | 0.00% | 0.00% | (604.97%) | (181.13%) | (865.83%) | (94.15%) | (63.73%) | (62.77%) |
ROIC
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| (75.55%) | (58.94%) | (40.41%) | (51.64%) | (54.34%) | (53.55%) | (70.61%) | (81.91%) | (57.48%) | (55.50%) |
ROE
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Iovance Biotherapeutics, Inc. peers in Biotechnology
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|---|---|---|---|
| DFTX Definium Therapeutics, Inc. | $4.9B | 0.0× | Compare |
| DNTH Dianthus Therapeutics, Inc. | $5.1B | 0.0× | Compare |
| ERAS Erasca, Inc. | $5.1B | 0.0× | Compare |
| PTCT PTC Therapeutics, Inc. | $5.2B | 0.0× | Compare |
| Company | Market cap | P/E | Compare |
|---|---|---|---|
| CRSP CRISPR Therapeutics AG | $5.4B | 0.0× | Compare |
| EWTX Edgewise Therapeutics, Inc. | $4.4B | 0.0× | Compare |
| COGT Cogent Biosciences, Inc. | $5.5B | 0.0× | Compare |
| VKTX Viking Therapeutics, Inc. | $4.3B | 0.0× | Compare |
Iovance Biotherapeutics, Inc. (IOVA) key facts
- Iovance Biotherapeutics, Inc. (IOVA) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
- Iovance Biotherapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $263.5 million, up 60.6% from fiscal 2024.
- As of September 25, 2026, IOVA traded at $11.00, a market capitalization of $4.9 billion.
- Return on equity was −55.5% and debt-to-equity 0.00.
Iovance Biotherapeutics, Inc. (IOVA) Latest News
24 Sep
Goldman Sachs analyst Andrea Newkirk resumed coverage of Iovance Biotherapeutics with a Buy rating and a $15 target, sending IOVA higher by about 6%. The note highlights stronger Q2 performance: Amtagvi generated $91 million in sales across 150 patients, with anticipated improvements in availability driving a potential upcycle. Newkirk cites proprietary survey data suggesting robust interest in Amtagvi as a second-line melanoma treatment, reinforcing an inflection point thesis after Amtagvi’s FDA approval in early 2024. The piece also notes commercialization hurdles easing and ongoing momentum. The Motley Fool references its Stock Advisor program cautioning against Iovance while contrasting past picks like Nvidia and Netflix; it also discloses Fool holdings in Goldman Sachs and Iovance. Overall, the Goldman upgrade and improving demand sentiment contributed to a positive day for Iovance stock. Goldman Sachs' Buy rating and a rising sentiment from improving Amtagvi demand may moderately influence near-term performance, but long-term trajectory remains contingent on sustained execution.
19 Sep
Iovance Biotherapeutics (IOVA) shares rose 19.2% after posting record Q2 Amtagvi revenue and advancing its TIL pipeline. Record Amtagvi revenue and TIL pipeline expansion mark major commercial and development progress with direct effects on future trajectory.
Iovance Biotherapeutics reports record revenue and margin gains while advancing plans to expand its TIL therapy. Record revenue, margin gains, and TIL therapy expansion represent major strategic and financial progress likely to shift company trajectory and investor views.
Iovance Biotherapeutics (IOVA) stock moved today on company developments. Single-company stock movement news can moderately sway near-term sentiment and trading without altering long-term trajectory.
Iovance Biotherapeutics (IOVA) stock fair value edges higher on Amtagvi margin progress. Amtagvi margin gains support modestly higher fair value and incremental financial improvement for Iovance.
17 Sep
IOVA stock rose more than 21% across four sessions. Barclays projects an additional 52% upside. Barclays positive price target adds to recent gains and supports further short-term investor interest without altering core operations.
15 Sep
Iovance Biotherapeutics reported record Amtagvi quarterly results and flagged upcoming year-end data readouts while stating a clear line of sight to profitability. Record product sales plus explicit profitability guidance indicate major positive effects on future financial trajectory and investor sentiment.
20 Aug
IOVA stock reaches new 52-week high after UBS raises price target amid melanoma sector optimism. UBS target increase lifts near-term sentiment and share price but leaves core operations and long-term trajectory unchanged.
13 Aug
Iovance Biotherapeutics Inc. (IOVA) held its Q2 2026 earnings call, covering financial results, operational updates and forward outlook. Quarterly earnings calls deliver financial results and guidance that can shift short-term sentiment without guaranteed long-term trajectory changes.
10 Aug
Iovance Biotherapeutics reported strong Q2 earnings that sent its stock sharply higher with questions remaining over further upside. Strong Q2 earnings lifted the stock but amount to a routine quarterly update without altering long-term trajectory.
7 Aug
Iovance Biotherapeutics beat Q2 earnings expectations with strong Amtagvi uptake driving a 43% stock jump. Q2 earnings beat and 43% stock surge on robust Amtagvi uptake signal major positive momentum for future performance.
Iovance Biotherapeutics held its Q2 2026 earnings call covering financial results, operational updates and future outlook. Q2 earnings call delivers key financial metrics and guidance that directly shape market expectations for Iovance.
Replimune secures FDA approval for its skin cancer drug after three attempts, but the company's stock declines following the decision. Competitor gains FDA approval in skin cancer space, creating moderate pressure on Iovance market positioning in related oncology treatments.
6 Aug
Iovance Biotherapeutics reported record revenue in its Q2 2026 earnings call. Record revenue from the earnings call points to major financial gains that can substantially shift company trajectory and investor outlook.
Iovance Biotherapeutics (IOVA) shares surged 43% after reporting strong Q2 results. Stellar Q2 results triggered a 43% stock surge and signal major positive momentum ahead.
IOVA shares surge toward best day in over 6 years on buyout speculation after strong Q2 results. Blowout Q2 and buyout buzz point to major ownership and valuation shifts ahead.
Iovance Biotherapeutics reported record Q2 revenue and issued a positive 2026 outlook driven by strong Amtagvi demand. Record revenue and surging Amtagvi demand indicate major growth trajectory and investor sentiment shift for Iovance.
Iovance Biotherapeutics reported record second quarter 2026 revenue of approximately $99 million along with business achievements and corporate updates. Record quarterly revenue of $99M signals strong financial growth likely to boost investor sentiment and company valuation.
Iovance Biotherapeutics Q2 earnings call highlighted financial results, pipeline progress, and operational updates for the company. Earnings call details can moderately shape near-term investor sentiment and operational perceptions for Iovance.
2 Aug
Iovance Biotherapeutics (IOVA) stock may be undervalued, with sales growth trajectory remaining the decisive factor for future value. Sales ramp is the pivotal factor that could moderately shift Iovance valuation and investor outlook.
1 Aug
Iovance Biotherapeutics approaches earnings with focus on its T cell therapy developments and company valuation. Earnings reports alongside T cell therapy updates can moderately affect financial outlook and investor sentiment.
23 Jun
Iovance Biotherapeutics stock rose 9.4% after securing regulatory approval. Regulatory approval directly lifts Iovance market trajectory and sentiment.
13 Jun
Amtagvi approval boosted Iovance Biotherapeutics shares but sustainability of the resulting rally is uncertain. Amtagvi approval constitutes a major regulatory milestone capable of substantially shifting company trajectory and investor sentiment.
10 Jun
Iovance Biotherapeutics gains FDA clearance for IOV-5001, advancing its next-generation TIL pipeline. FDA clearance for IOV-5001 enables pipeline progression and strengthens competitive positioning in TIL therapies.
7 Jun
Iovance Biotherapeutics (IOVA) is positioned as a top penny stock to buy on the back of strong Amtagvi adoption. Strong Amtagvi adoption signals major commercial traction that can lift revenue trajectory and investor sentiment.
6 Jun
Iovance Biotherapeutics receives Australian conditional approval for Amtagvi, triggering updated valuation assessment for the company. Australian conditional approval for Amtagvi expands market access and revenue potential for Iovance.
4 Jun
Iovance Biotherapeutics receives Australian regulatory approval for Amtagvi, driving a 15% stock climb. Australian approval expands Amtagvi market access and triggers major immediate stock gains for Iovance.
3 Jun
Iovance Biotherapeutics obtained regulatory approval in Australia for Amtagvi (lifileucel) to treat advanced melanoma. Australian approval for lead therapy Amtagvi opens new revenue market and strengthens global positioning.
1 Jun
FDA clears Iovance Biotherapeutics IOV-5001 TIL-IL12 trial, prompting assessment of whether this advances the company's bull case. FDA clearance for new IOV-5001 trial advances Iovance pipeline and can materially shift company trajectory plus investor views.
Iovance Biotherapeutics secured FDA clearance for its IND application for IL-12 Tethered TIL Therapy IOV-5001. IND clearance advances pipeline via new therapy but remains early-stage with limited immediate trajectory shift.