Iovance Biotherapeutics, Inc.

IOVA Healthcare Biotechnology

Iovance Biotherapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $263.5 million, up 60.6% from fiscal 2024.

Revenue
+80.1%
EPS
+80.0%
Free cash flow
+89.7%

Quarter to September 2026, against a year earlier

7.99 0.25 +3.23%
Market cap
$3.5B
P/E
0.0×
Fwd P/E
−18.9×
Dividend yield
—
F-score
4/9
Altman Z
−2.30
Beneish M
−2.46
Dividend safety
n/a

Iovance Biotherapeutics, Inc. (IOVA) Return on invested capital

Alert me on Return on invested capital

Iovance Biotherapeutics, Inc.'s return on invested capital over the twelve months to 30 September 2026 was −17.7%, up 45.0 percentage points from fiscal 2025 (−62.8%). Over the past ten years it has ranged from −53,748.3% (fiscal 2017) to 0.00% (fiscal 2019); the current reading is higher than 82% of that period. That is below the Biotechnology industry median of 0.00% and below the Healthcare sector median of 0.00%.

Return on invested capital, annual

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Annual newest first

Period Return on invested capital Change (points)
FY2025 −62.8% 0.96
FY2024 −63.7% 30.42
FY2023 −94.2% 771.68
FY2022 −865.8% (684.70)
FY2021 −181.1% 423.84
FY2020 −605.0% (604.97)
FY2019 0.00% 0.00
FY2018 0.00% 53,748.26
FY2017 −53,748.3% (46,265.14)
FY2016 −7,483.1% (2,092.25)

Against its own ten years

Low −53,748.3% High 0.00%
Ten-year median −181.1%
Current reading's percentile 82

Return on invested capital against peers

Company Return on invested capital
ACAD ACADIA Pharmaceuticals Inc. compare 18.6%
RLAY Relay Therapeutics, Inc. compare 0.00%
IRON Disc Medicine, Inc. compare 0.00%
EWTX Edgewise Therapeutics, Inc. compare 0.00%
PBLS Parabilis Medicines, Inc. compare 0.00%
IOVA Iovance Biotherapeutics, Inc. −17.7%
ABCL AbCellera Biologics Inc. compare −42.5%
XENE Xenon Pharmaceuticals Inc. compare −88.5%
TNGX Tango Therapeutics, Inc. compare −808.4%
Biotechnology industry median 0.00%
Healthcare sector median 0.00%
Market median 0.00%

What Return on invested capital is

Return on Invested Capital shows how much after-tax operating profit a company earns on the money its lenders and shareholders have put in.

TTM: (Operating Income × 0.625) ÷ (Shareholders Equity (Total) (latest quarter) + Long Term Debt (Total) (latest quarter) + Current Part of Debt (latest quarter) − Cash & Short Term Investments (latest quarter)); Annual: (Operating Income × 0.625) ÷ (Shareholders Equity (Total) + Long Term Debt (Total) + Current Part of Debt − Cash & Short Term Investments)

The full definition of Return on invested capital →

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