Dyne Therapeutics, Inc.

DYN Healthcare Biotechnology

In the quarter to June 2026, EPS fell 11.3%, free cash flow fell 39.1% and total debt rose 116.0%, each against the same quarter a year earlier. Insiders bought in the last twelve months.

14.25 1.04 −6.80%
Market cap
$2.9B
P/E
0.0×
Fwd P/E
—
Dividend yield
—
F-score
n/a
Altman Z
n/a
Beneish M
n/a
Dividend safety
n/a

Insider Decisions trades per month

Total buys 0.31
Total sells 168.62
Totals in millions of $.
Dec 25 Mar 26 Jun 26 Sep 26
Buy — — — — 3 — 2 2 — — — 1
Sell — 3 — — 5 7 5 8 2 5 3 —
Insider Ownership 7.33%

Capital & Financial Ratios $m

Market Cap 2,860.00
Revenue —
Net Income (519.40)
Free Cash Flow (480.43)
Net Debt (685.00)
Current Ratio 12.02 (at or above 1.5: strong)
Debt/Equity 0.30 (at or below 0.5: strong)
P/E ratio 0.00
Fwd P/E —
P/S ratio 0.00
P/B ratio 3.36
Past 5Y EPS Growth —
This Y EPS Growth (4.49%) (below 0%: weak)
Next Y EPS Growth 7.67%
Next Y revenue growth —
Next 5Y EPS Growth 10.00%

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/B against its own 10 years 67.81%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2023 Powerpack
2022 Powerpack
2021 Powerpack
special payouts not included in total or ratios

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 123 642 1,111 898
Receivables — — — —
Inventory — — — —
Other — — — —
129 659 1,127 938
2023 2024 2025 Q'26
Payables 23 7 8 12
ST’ Debt — — — 14
Other — — — —
51 42 51 78

Compound Annual Growth %

10y 5y 3y
Sales — — —
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — 23.21% 56.76%

Revenue $m

Year
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (145) (130) — — —
’25 (106) (95) (91) (112) (403)
’24 (79) (55) (75) (84) (292)
’23 (47) (56) (51) (35) (188)
’22 (51) (31) (43) (29) (154)
’21 (18) (46) (27) (28) (120)
’20 (7) (7) (12) (20) (47)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (145) (132) — — —
’25 (107) (95) (91) (112) (405)
’24 (79) (56) (75) (85) (295)
’23 (47) (56) (51) (35) (189)
’22 (52) (31) (44) (30) (157)
’21 (18) (47) (28) (30) (123)
’20 (7) (7) (12) (21) (48)
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 (0.73) (1.08) — — —
’25 (1.05) (0.97) (0.76) (0.76) (3.47)
’24 (0.81) (0.70) (0.96) (0.88) (3.37)
’23 (0.78) (1.08) (0.99) (1.09) (3.95)
’22 (0.69) (1.01) (0.80) (0.74) (3.23)
’21 (0.50) (0.58) (0.83) (1.00) (2.93)
’20 (0.90) (3.31) (2.01) (0.64) (4.13)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1.3
1Buy 2 3Hold 4 5Sell

Ten years at a glance

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low — — — — 15.60 11.57 4.30 6.40 12.33 6.36

Analyst estimates 2026–2028

Powerpack
High — — — — 27.11 32.32 15.63 15.60 47.45 26.22
People
People Employees — — — — 47 95 123 141 191 258
Revenue/emp, $m — — — — 0.00 0.00 0.00 0.00 0.00 0.00
Income, $m
Income, $m Revenue — — — — — — — — — —
Gross margin, % — — 0.00 0.00 0.00 0.00 0.00 — — —
EBT — — (5) (15) (59) (149) (168) (236) (317) (446)
EBT margin, % — — 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Net income — 0 (5) (15) (59) (149) (168) (236) (317) (446)
Depreciation — — 0 0 1 4 3 1 (2) 0
Per share, $
Per share, $ Revenue — — 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Earnings — — (0.11) (6.08) (4.13) (2.93) (3.23) (3.95) (3.37) (3.47)
Cash flow — — (0.09) (4.84) (3.23) (2.35) (2.96) (3.15) (3.11) (3.14)
Capex — — 0.00 (0.67) (0.08) (0.07) (0.06) (0.01) (0.03) (0.01)
Free cash flow — — (0.09) (5.52) (3.31) (2.42) (3.02) (3.16) (3.13) (3.15)
Book value — — 0.09 5.75 23.78 7.23 4.86 1.53 6.69 7.57
Shares, m — — 45 2 14 51 52 60 94 128
Valuation, ×
Valuation, × P/E — — — — — — — — — —
P/S — — — — — — — — — —
P/B — — — — — — — — — —
EV/Sales — — — — — — — — — —
EV/FCF — — — — — — — — — —
Cash, $m
Cash, $m Operating cash flow — — (4) (12) (47) (120) (154) (188) (292) (403)
Capex — — 0 (2) (1) (4) (3) (1) (2) (2)
Free cash flow — — (4) (13) (48) (123) (157) (189) (295) (405)
Balance, $m
Balance, $m Working capital — — 7 12 338 354 238 78 617 1,076
Total debt — — 3 — — 29 26 — — 149
Net debt — — (5) (15) (345) (348) (230) (123) (642) (962)
Shareholders’ equity — — 4 14 342 368 252 91 630 972
Returns, %
Returns, % ROA — — (116.38) (120.30) (32.15) (38.33) (45.93) (100.10) (74.14) (47.52)
ROIC — — 0.00 0.00 0.00 (460.33) (480.77) 0.00 0.00 (2,790.00)
ROE — — 52.66 162.64 (36.13) (42.02) (54.18) (137.31) (88.03) (55.71)
Negative figures in brackets.

All 10 years →

Charts ten years each

Dyne Therapeutics, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
CELC Celcuity, Inc. $3.0B — (loss-making) — — n/m −53.27% (below 0%: shrinking) 0.00% 0.00% Compare
DNLI Denali Therapeutics Inc. $2.9B — (loss-making) — (loss-making) −89.74% (below 0%: shrinking) n/m −22.91% (below 0%: shrinking) 97.42% (3,622.11%) Compare
RCUS Arcus Biosciences, Inc. $2.9B — (loss-making) — (loss-making) −74.38% (below 0%: shrinking) n/m +10.53% (above 0%: growing) 100.00% (234.15%) Compare
ELVN Enliven Therapeutics, Inc. $2.9B — (loss-making) — — n/m −8.34% (below 0%: shrinking) 0.00% 0.00% Compare
DYN Dyne Therapeutics, Inc. $2.9B — (loss-making) — — n/m −39.08% (below 0%: shrinking) 0.00% 0.00%
NRIX Nurix Therapeutics, Inc. $2.7B 9.7× — (loss-making) +8,426.27% (above 0%: growing) n/m +1,122.10% (above 0%: growing) 100.00% 83.12% Compare
ZLAB Zai Lab Limited Unsponsored ADR $2.7B — (loss-making) — (loss-making) −3.33% (below 0%: shrinking) n/m −84.42% (below 0%: shrinking) 54.70% (71.95%) Compare
PGEN Precigen, Inc. $2.6B — (loss-making) — (loss-making) +6,322.66% (above 0%: growing) n/m +8.73% (above 0%: growing) 94.90% 41.18% Compare
BEAM Beam Therapeutics Inc. $2.6B — (loss-making) — (loss-making) −94.21% (below 0%: shrinking) n/m +13.92% (above 0%: growing) 100.00% (25,827.14%) Compare
Median of peers $2.8B — — −38.85% — +0.20% 96.16% (35.97%)

All 614 Biotechnology stocks →

Dyne Therapeutics, Inc. (DYN) key facts

  • Dyne Therapeutics, Inc. (DYN) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • As of October 16, 2026, DYN traded at $14.25, a market capitalization of $2.9 billion.
  • Return on equity was −55.7% and debt-to-equity 0.30.

Source: company filings (standardised) and stockrow calculations.

Dyne Therapeutics, Inc. (DYN) Latest News

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