Dyne Therapeutics, Inc. DYN

16.03 (0.48) (2.91%) as of 25 Sep
Market cap
$3.1B
P/E
0.0×
Insider Buys alert about insiders buying in the last 12 month

Insider Decisions

Total buys 0.27
Total sells 168.62
in millions of $
Nov 25 Feb 26 May 26 Aug 26
Buy — — — — — 3 — 2 2 — — —
Sell — — 3 — — 5 7 5 8 2 5 3
Insider Ownership 4.97%

Capital & Financial Ratios

Market Cap 3,140.00
Revenue —
Net Income (519.40)
Free Cash Flow (480.43)
Net Debt (685.00)
Current Ratio 12.02
Debt/Equity 0.30
P/E ratio 0.00
P/S ratio 0.00
P/B ratio 3.78
Past 5Y EPS Growth (59.45%)
This Y EPS Growth (4.49%)
Next Y EPS Growth 7.66%
Next 5Y EPS Growth 10.08%
in millions of $

Dividends

Payout Ratio 0.00
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2023 Powerpack
2022 Powerpack
2021 Powerpack
predictions in italic, special payouts not included in total or ratios

Assets vs Liabilities

2023 2024 2025 Q'26
Cash 123 642 1,111 898
Receivables — — — —
Inventory — — — —
Other — — — —
129 659 1,127 938
2023 2024 2025 Q'26
Payables 23 7 8 12
ST’ Debt — — — 14
Other — — — —
51 42 51 78
in millions of $

Compound Annual Growth

10y 5y 3y
Sales — — —
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — 23.21% 56.76%

Revenue

Year
in millions of $ · fiscal quarters ending in the months shown

Operating Cash Flow

Mar Jun Sep Dec Year
’26 (145) (130) — — —
’25 (106) (95) (91) (112) (403)
’24 (79) (55) (75) (84) (292)
’23 (47) (56) (51) (35) (188)
’22 (51) (31) (43) (29) (154)
’21 (18) (46) (27) (28) (120)
’20 (7) (7) (12) (20) (47)
in millions of $ · fiscal quarters ending in the months shown

Free Cash Flow

Mar Jun Sep Dec Year
’26 (145) (132) — — —
’25 (107) (95) (91) (112) (405)
’24 (79) (56) (75) (85) (295)
’23 (47) (56) (51) (35) (189)
’22 (52) (31) (44) (30) (157)
’21 (18) (47) (28) (30) (123)
’20 (7) (7) (12) (21) (48)
in millions of $ · fiscal quarters ending in the months shown

EPS

Mar Jun Sep Dec Year
’26 (0.73) (1.08) — — —
’25 (1.05) (0.97) (0.76) (0.76) (3.47)
’24 (0.81) (0.70) (0.96) (0.88) (3.37)
’23 (0.78) (1.08) (0.99) (1.09) (3.95)
’22 (0.69) (1.01) (0.80) (0.74) (3.23)
’21 (0.50) (0.58) (0.83) (1.00) (2.93)
’20 (0.90) (3.31) (2.01) (0.64) (4.13)
fiscal quarters ending in the months shown

Target Price Range

Analyst price targets

Recommendation Rating

1.3
1Buy 2 3Hold 4 5Sell
2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 2027 2028
— — — — 15.60 11.57 4.30 6.40 12.33 6.36

Analyst estimates 2026–2028

Powerpack
Low Price
— — — — 27.11 32.32 15.63 15.60 47.45 26.22
High Price
— — — — 47 95 123 141 191 258
Employees
— — — — 0 0 0 0 0 0
Revenue/Emp
— — — — — — — — — —
Revenue
— — 0.00% 0.00% 0.00% 0.00% 0.00% — — —
Gross Margin
— — (5) (15) (59) (149) (168) (236) (317) (446)
EBT
— — 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
EBT Margin
— 0 (5) (15) (59) (149) (168) (236) (317) (446)
Net Income
— — 0 0 1 4 3 1 (2) 0
Depreciation
— — 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Revenue/Sh
— — (0.11) (6.08) (4.13) (2.93) (3.23) (3.95) (3.37) (3.47)
Earnings/Sh
— — (0.09) (4.84) (3.23) (2.35) (2.96) (3.15) (3.11) (3.14)
Cash Flow/Sh
— — 0.00 (0.67) (0.08) (0.07) (0.06) (0.01) (0.03) (0.01)
Capex/Sh
— — (0.09) (5.52) (3.31) (2.42) (3.02) (3.16) (3.13) (3.15)
Free CF/Sh
— — 0.09 5.75 23.78 7.23 4.86 1.53 6.69 7.57
Book Value/Sh
— — 45 2 14 51 52 60 94 128
Shares
— — — — — — — — — —
PE Ratio
— — — — — — — — — —
PS Ratio
— — — — — — — — — —
PB Ratio
— — — — — — — — — —
EV/Sales
— — — — — — — — — —
EV/FCF
— — (4) (12) (47) (120) (154) (188) (292) (403)
Op' Cash Flow
— — 0 (2) (1) (4) (3) (1) (2) (2)
Capex
— — (4) (13) (48) (123) (157) (189) (295) (405)
FCF
— — 7 12 338 354 238 78 617 1,076
Working Cap'
— — 3 — — 29 26 — — 149
Total Debt
— — (5) (15) (345) (348) (230) (123) (642) (962)
Net Debt
— — 4 14 342 368 252 91 630 972
Sh' Equity
— — (116.38%) (120.30%) (32.15%) (38.33%) (45.93%) (100.10%) (74.14%) (47.52%)
ROA
— — 0.00% 0.00% 0.00% (460.33%) (480.77%) 0.00% 0.00% (2,790.00%)
ROIC
— — 52.66% 162.64% (36.13%) (42.02%) (54.18%) (137.31%) (88.03%) (55.71%)
ROE
predictions in italic, sparklines do not include predictions

All 10 years →

Dyne Therapeutics, Inc. (DYN) key facts

  • Dyne Therapeutics, Inc. (DYN) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • As of September 25, 2026, DYN traded at $16.03, a market capitalization of $3.1 billion.
  • Return on equity was −55.7% and debt-to-equity 0.30.

Source: company filings (standardised) and stockrow calculations.

Dyne Therapeutics, Inc. (DYN) Latest News

News by impact score

Fine-tune

17 Sep

4

Dyne Therapeutics releases expanded DM1 data presentations that may redefine its rare-disease investment narrative. Expanded DM1 clinical data presentations carry potential to significantly shift Dyne Therapeutics' valuation and investor sentiment.

9 Sep

4

Novartis Phase 3 failure triggers Wall Street review of DYN stock; RBC cites key differences that could produce better outcomes for Dyne Therapeutics. RBC analysis of differentiating factors positions DYN for stronger clinical and market results than Novartis.

3

RBC states Dyne Therapeutics' Myotonic Dystrophy approach remains differentiated. Analyst note affirming differentiation of key program supports positive sentiment around Dyne's pipeline.

8 Sep

4

Novartis shares fell after del-desiran failed its Phase 3 trial for myotonic dystrophy. Novartis Phase 3 failure in myotonic dystrophy reduces competition for Dyne's candidate and lifts its prospects.

3

Dyne Therapeutics will present one-year clinical data from Phase 1/2 ACHIEVE trial of DYNE-101 for DM1 at upcoming medical meetings. Presentation of additional trial data may moderately shift investor views on pipeline progress without guaranteeing immediate commercial outcomes.

3

Dyne Therapeutics shares fell 31% in premarket trading with no catalyst confirmed for the decline. Unexplained 31% share drop can affect short-term sentiment without altering long-term company trajectory.

29 Jul

3

Dyne Therapeutics reported second quarter 2026 financial results and recent business highlights. Quarterly financials and business updates typically influence near-term investor views without major strategic shifts.

28 Jul

4

Dyne Therapeutics secures U.S. FDA clearance for its IND application for DYNE-302 in facioscapulohumeral muscular dystrophy. IND clearance directly advances DYNE-302 into clinical trials for FSHD strengthening the company's core pipeline.

23 Jul

3

Dyne Therapeutics closes upsized public offering of common stock with underwriters fully exercising option for additional shares. Upsized equity raise supplies Dyne with fresh capital while increasing share count and affecting near-term valuation.

3

Dyne Therapeutics priced an upsized share offering and questioned if valuation remains compelling. Upsized share offering raises capital but dilutes equity and pressures near-term valuation.

22 Jul

3

SRPT shares fell 10% over the past week as investors assess whether Dyne Therapeutics poses a competitive threat. Dyne Therapeutics is positioned as a potential rival that could shift competitive dynamics and investor attention.

3

Dyne Therapeutics priced a $375 million public offering, triggering a slide in its shares. Public offering raises capital via share dilution that can pressure stock price in the near term.

21 Jul

3

Dyne Therapeutics priced an upsized $375 million public offering of common stock. Large equity raise supplies substantial capital but triggers share dilution without altering core pipeline trajectory.

3

DYN shares fell 10% after-hours on a new announcement one day after an FDA win. FDA win and subsequent announcement drove immediate 10% stock drop indicating moderate effects on near-term sentiment.

3

Dyne Therapeutics announced a proposed public offering of common stock. Equity offering raises operating capital but dilutes shareholders and pressures near-term stock price.

3

Citi flagged Dyne Therapeutics as a potentially stronger rival to Sarepta in the Duchenne space, triggering a 4% drop in SRPT stock. Citi note elevates Dyne's profile as a Duchenne competitor and may lift investor attention.

20 Jul

4

Sarepta shares declined after Dyne Therapeutics advanced a Duchenne muscular dystrophy candidate past a key regulatory or clinical milestone. Dyne's clinical progress in Duchenne directly pressures Sarepta and elevates Dyne's competitive standing and investor visibility.

4

Dyne Therapeutics announced U.S. FDA acceptance of BLA for Z-Rostudirsen in Exon 51 DMD. BLA acceptance advances lead DMD candidate toward potential approval.

15 Jul

3

Dyne Therapeutics' Force Platform generates positive sentiment around the company's development efforts and outlook. Force Platform news may lift sentiment and visibility but does not signal immediate major financial or regulatory shifts.

17 Jun

3

Dyne Therapeutics expanded its debt facility with Hercules Capital to up to $400 million. Up to $400 million debt facility supplies Dyne Therapeutics additional capital to support operations and development programs.

11 Jun

3

Dyne Therapeutics completed enrollment for its Phase 1/2 ACHIEVE trial. Phase 1/2 enrollment completion advances the clinical pipeline without ensuring data success or major commercial shifts.

5 Jun

4

Dyne Therapeutics (DYN) achieves a key regulatory milestone. Regulatory milestone advances Dyne Therapeutics development timeline and investor outlook.

4 Jun

3

Dyne Therapeutics reached key ACHIEVE trial enrollment milestone, triggering updated valuation assessment for DYN. ACHIEVE enrollment milestone marks clinical progress that may moderately shift investor views on DYN.

3 Jun

4

Dyne Therapeutics completed enrollment in the registrational expansion cohort of the ACHIEVE trial evaluating Z-Basivarsen for Myotonic Dystrophy Type 1. Trial enrollment completion marks key clinical milestone that advances Z-Basivarsen toward data readout and potential regulatory approval.

30 May

4

A fund invested $66 million in Dyne Therapeutics (DYN) following a 700% stock surge. Large fund bet amid 700% surge signals major positive shift in market dynamics and investor sentiment for Dyne Therapeutics.

27 May

4

Dyne Therapeutics, Inc. (DYN) stock gained 4.5% after BLA filing for DMD therapy. BLA filing advances core DMD therapy program toward potential approval and commercialization.

26 May

4

Dyne Therapeutics submitted a Biologics License Application to the U.S. FDA for Z-Rostudirsen in Exon 51 Duchenne Muscular Dystrophy. BLA submission advances Z-Rostudirsen toward potential approval and commercialization, materially shifting company trajectory.

21 May

4

Dyne Therapeutics initiated a late-stage study in DMD patients, driving a 10% stock gain. Late-stage DMD trial initiation advances core pipeline asset and can materially shift company valuation and trajectory.

4

Dyne Therapeutics advances its Phase 3 FORZETTO trial as a key development milestone that shapes current valuation analysis for the company. Phase 3 FORZETTO trial milestone advances lead asset toward potential approval and directly influences future revenue prospects.

20 May

4

Dyne Therapeutics initiates Phase 3 trial of potential Duchenne Muscular Dystrophy treatment. Phase 3 trial start for Duchenne Muscular Dystrophy candidate advances Dyne Therapeutics toward possible regulatory approval and commercial revenue.

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