Illumina, Inc.

ILMN Healthcare Diagnostics & Research

Illumina, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $4.3 billion, down 0.66% from fiscal 2024. In the quarter to June 2026, revenue grew 9.44%, EPS fell 8.05%, free cash flow fell 18.3% and total debt was flat, each against the same quarter a year earlier. Member of the S&P 500; operating cash flow growth for three consecutive years; insiders bought in the last twelve months.

262.03 5.90 −2.20%
Market cap
$40.5B
P/E
48.4×
Fwd P/E
34.7×
Dividend yield
—
F-score
8/9
Altman Z
4.39
Beneish M
−2.51
Dividend safety
n/a

Illumina, Inc. (ILMN) Return on invested capital

Alert me on Return on invested capital

Illumina, Inc.'s return on invested capital over the twelve months to 30 June 2026 was 17.5%, down 2.1 percentage points from fiscal 2025 (19.6%). Over the past ten years it has ranged from −43.2% (fiscal 2022) to 25.8% (fiscal 2019); the current reading is higher than 55% of that period. That is above the Diagnostics & Research industry median of 0.00% and above the Healthcare sector median of 0.00%.

Return on invested capital, annual

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Annual newest first

Period Return on invested capital Change (points)
FY2025 19.6% 39.25
FY2024 −19.7% (8.89)
FY2023 −10.8% 32.37
FY2022 −43.2% (42.49)
FY2021 −0.69% (15.76)
FY2020 15.1% (10.74)
FY2019 25.8% 2.12
FY2018 23.7% 2.60
FY2017 21.1% 0.35
FY2016 20.7% (3.93)

Against its own ten years

Low −43.2% High 25.8%
Ten-year median 19.6%
Current reading's percentile 55

Return on invested capital against peers

Company Return on invested capital
IDXX IDEXX Laboratories, Inc. compare 48.9%
MTD Mettler-Toledo International, Inc. compare 35.4%
ILMN Illumina, Inc. 17.5%
A Agilent Technologies, Inc. compare 11.1%
DGX Quest Diagnostics Incorporated compare 7.94%
IQV IQVIA Holdings Inc. compare 6.80%
LH Labcorp Holdings Inc. compare 6.50%
WAT Waters Corporation compare 1.05%
NTRA Natera, Inc. compare −22.3%
Diagnostics & Research industry median 0.00%
Healthcare sector median 0.00%
Market median 0.00%

What Return on invested capital is

Return on Invested Capital shows how much after-tax operating profit a company earns on the money its lenders and shareholders have put in.

TTM: (Operating Income × 0.625) ÷ (Shareholders Equity (Total) (latest quarter) + Long Term Debt (Total) (latest quarter) + Current Part of Debt (latest quarter) − Cash & Short Term Investments (latest quarter)); Annual: (Operating Income × 0.625) ÷ (Shareholders Equity (Total) + Long Term Debt (Total) + Current Part of Debt − Cash & Short Term Investments)

The full definition of Return on invested capital →

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