Illumina, Inc.

ILMN Healthcare Diagnostics & Research

Illumina, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $4.3 billion, down 0.66% from fiscal 2024.

Revenue
+4.15%
EPS
+49.0%
Free cash flow
+49.8%
Total debt
+80.0%

Quarter to September 2026, against a year earlier

209.82 16.72 −7.38%
Market cap
$31.5B
P/E
35.6×
Fwd P/E
46.4×
Dividend yield
—
F-score
8/9
Altman Z
4.39
Beneish M
−2.51
Dividend safety
n/a

Illumina, Inc. (ILMN) Operating margin

Alert me on Operating margin

Illumina, Inc.'s operating margin over the twelve months to 30 September 2026 was 21.2%, up 2.6 percentage points from fiscal 2025 (18.6%). Over the past ten years it has ranged from −91.2% (fiscal 2022) to 27.8% (fiscal 2019); the current reading is higher than 55% of that period. That is above the Diagnostics & Research industry median of −5.68% and above the Healthcare sector median of 0.00%.

Operating margin, annual

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Annual newest first

Period Operating margin Change (points)
FY2025 18.6% 37.63
FY2024 −19.1% 4.68
FY2023 −23.7% 67.43
FY2022 −91.2% (88.44)
FY2021 −2.72% (20.63)
FY2020 17.9% (9.89)
FY2019 27.8% 1.31
FY2018 26.5% 4.47
FY2017 22.0% (2.46)
FY2016 24.5% (3.13)

Quarterly newest first

Period Operating margin Change (points)
Sep 2026 27.0% 5.88
Jun 2026 21.1% 1.98
Mar 2026 19.2% 1.73
Dec 2025 17.4% (3.51)
43 more quarters

Against its own ten years

Low −91.2% High 27.8%
Ten-year median 18.6%
Current reading's percentile 58

Operating margin against peers

Company Operating margin
IDXX IDEXX Laboratories, Inc. compare 32.3%
MTD Mettler-Toledo International, Inc. compare 28.4%
A Agilent Technologies, Inc. compare 22.2%
ILMN Illumina, Inc. 21.2%
DGX Quest Diagnostics Incorporated compare 14.6%
IQV IQVIA Holdings Inc. compare 12.8%
LH Labcorp Holdings Inc. compare 10.3%
WAT Waters Corporation compare 4.73%
GH Guardant Health, Inc. compare −39.4%
Diagnostics & Research industry median −5.68%
Healthcare sector median 0.00%
Market median 0.00%

What Operating margin is

EBIT Margin tells an investor how much operating profit, before interest and taxes, a company keeps from each unit of revenue.

EBIT ÷ Revenue

The full definition of Operating margin →

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