Illumina, Inc.

ILMN Healthcare Diagnostics & Research

Illumina, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $4.3 billion, down 0.66% from fiscal 2024. In the quarter to June 2026, revenue grew 9.44%, EPS fell 8.05%, free cash flow fell 18.3% and total debt was flat, each against the same quarter a year earlier. Member of the S&P 500; operating cash flow growth for three consecutive years; insiders bought in the last twelve months.

262.03 5.90 −2.20%
Market cap
$40.5B
P/E
48.4×
Fwd P/E
34.7×
Dividend yield
—
F-score
8/9
Altman Z
4.39
Beneish M
−2.51
Dividend safety
n/a

Insider Decisions trades per month

Total buys 0.08
Total sells 592.86
Totals in millions of $.
Dec 25 Mar 26 Jun 26 Sep 26
Buy 1 — — 1 — — — — — — — —
Sell — 2 — 2 — — 5 3 1 4 1 —
Insider Ownership 0.34%

Capital & Financial Ratios $m

Market Cap 40,460.00
Revenue 4,493.00
Net Income 824.00
Free Cash Flow 931.00
Net Debt 323.00
Current Ratio 1.80 (at or above 1.5: strong)
Debt/Equity 0.53
P/E ratio 48.43 (above 35: high)
Fwd P/E 34.70
P/S ratio 8.81
P/B ratio 13.94 (above 6: high)
Past 5Y EPS Growth 4.14%
This Y EPS Growth 10.65%
Next Y EPS Growth 13.84%
Next Y revenue growth 6.47%
Next 5Y EPS Growth 12.98%

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/E against its own 10 years 47.20%
10-year low 10-year high
P/S against its own 10 years 43.90%
10-year low 10-year high
P/B against its own 10 years 96.31%
10-year low 10-year high
EV/Sales against its own 10 years 45.04%
10-year low 10-year high
EV/FCF against its own 10 years 31.08%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2025 Powerpack
2024 Powerpack
2023 Powerpack
2022 Powerpack
2021 Powerpack
2020 Powerpack
2019 Powerpack
2017 Powerpack
predictions special payouts not included in total or ratios

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 1,054 1,220 1,633 1,168
Receivables 734 735 854 764
Inventory 587 547 564 629
Other — — — —
2,609 2,746 3,289 2,834
2023 2024 2025 Q'26
Payables 245 221 240 230
ST’ Debt — — — —
Other — — — —
1,570 1,547 1,585 1,578

Compound Annual Growth %

10y 5y 3y
Sales 6.94% 6.04% (1.78%)
Cash Flow 3.22% (0.02%) 40.15%
Earnings 6.29% 5.32% 0.00%
Book Value 3.95% (10.32%) (25.55%)

Revenue $m

Mar Jun Sep Dec Year
’26 1,091 1,159 — — —
’25 1,041 1,059 1,084 1,159 4,343
’24 1,076 1,112 1,080 1,104 4,372
’23 1,087 1,176 1,119 1,122 4,504
’22 1,223 1,162 1,115 1,084 4,584
’21 1,093 1,126 1,108 1,199 4,526
’20 859 633 794 953 3,239
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 289 201 — — —
’25 240 234 284 321 1,079
’24 77 80 316 364 837
’23 10 105 139 224 478
’22 172 125 (52) 147 392
’21 282 253 (272) 282 545
’20 281 240 153 406 1,080
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 251 161 — — —
’25 201 197 253 266 931
’24 41 49 284 335 709
’23 (43) 58 94 172 282
’22 111 54 (298) 59 (74)
’21 240 209 (324) 212 337
’20 241 201 105 344 891
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 0.87 1.35 — — —
’25 0.82 1.49 0.98 2.16 5.45
’24 (0.79) (12.48) 4.42 1.17 (7.69)
’23 0.02 (1.48) (4.77) (1.11) (7.34)
’22 0.55 (3.40) (24.26) (0.89) (28.00)
’21 1.00 1.26 2.08 0.71 5.04
’20 1.17 0.32 1.21 1.75 4.45
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

2.4
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low 116.12 124.67 201.86 256.13 191.42 331.74 168.73 86.58 97.36 68.70

Analyst estimates 2026–2028

Powerpack
High 183.12 224.44 362.46 370.39 393.19 540.63 416.34 232.05 156.66 153.06
People
People Employees 5,500 6,200 7,300 7,700 7,850 9,150 10,260 9,300 9,030 8,650
Revenue/emp, $m 0.44 0.44 0.46 0.46 0.41 0.49 0.45 0.48 0.48 0.50
Income, $m
Income, $m Revenue 2,398 2,752 3,333 3,543 3,239 4,526 4,584 4,504 4,372 4,343
Gross margin, % 69.47 66.35 69.01 69.63 68.01 69.69 64.83 60.92 65.44 66.08
EBT 561 1,043 894 1,118 856 884 (4,336) (1,117) (1,179) 1,086
EBT margin, % 23.39 37.90 26.82 31.56 26.43 19.53 (94.59) (24.80) (26.97) 25.01
Net income 428 678 782 990 656 762 (4,404) (1,161) (1,223) 850
Depreciation 171 186 220 234 227 283 394 432 354 270
Per share, $
Per share, $ Revenue 16.31 18.85 22.67 24.10 22.03 30.17 29.20 28.51 27.50 28.02
Earnings 3.09 4.96 5.63 6.81 4.48 5.07 (28.00) (7.34) (7.69) 5.47
Cash flow 5.30 5.99 7.77 7.15 7.35 3.63 2.50 3.03 5.26 6.96
Capex (1.84) (2.14) (2.01) (1.42) (1.29) (1.39) (2.97) (1.24) (0.80) (0.95)
Free cash flow 3.46 3.86 5.76 5.73 6.06 2.25 (0.47) 1.78 4.46 6.01
Book value 15.44 18.83 26.16 31.38 31.93 71.60 42.03 36.36 14.92 17.57
Shares, m 147 146 147 147 147 150 157 158 159 155
Valuation, ×
Valuation, × P/E 40.50 43.59 51.91 47.39 80.34 72.71 0.00 0.00 0.00 23.93
P/S 7.82 11.56 12.87 13.39 16.33 12.27 6.69 4.70 4.86 4.68
P/B 8.26 11.57 11.15 10.28 11.27 5.17 4.65 3.68 8.95 7.47
EV/Sales 7.61 11.22 12.41 12.76 15.63 12.45 6.68 4.90 5.03 4.76
EV/FCF 35.95 55.91 49.67 54.53 57.65 173.94 (402.84) 78.55 31.12 22.57
Cash, $m
Cash, $m Operating cash flow 779 875 1,142 1,051 1,080 545 392 478 837 1,079
Capex (271) (312) (296) (209) (189) (208) (466) (196) (128) (148)
Free cash flow 508 563 846 842 891 337 (74) 282 709 931
Balance, $m
Balance, $m Working capital 1,613 2,234 2,686 3,786 3,239 1,620 788 1,039 1,199 1,704
Total debt 1,058 1,192 1,997 1,186 1,184 1,695 1,487 1,489 1,490 1,490
Net debt (501) (953) (1,515) (2,228) (2,288) 356 (550) 435 270 (143)
Shareholders’ equity 2,270 2,749 3,845 4,613 4,694 10,740 6,599 5,745 2,373 2,723
Returns, %
Returns, % ROA 11.62 15.22 13.52 14.04 8.80 6.68 (32.07) (10.38) (14.90) 13.13
ROIC 20.74 21.09 23.69 25.81 15.07 (0.69) (43.18) (10.81) (19.70) 19.55
ROE 22.48 28.93 25.05 23.69 14.10 9.87 (50.80) (18.81) (30.13) 33.36
Negative figures in brackets.

All 10 years →

Fiscal years to Dec 2025 · latest quarter Jun 2026

Charts ten years each

Illumina, Inc. vs peers in Diagnostics & Research (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
NTRA Natera, Inc. $58.4B — (loss-making) — (loss-making) +37.71% (above 0%: growing) n/m −173.96% (below 0%: shrinking) 64.46% (10.07%) Compare
A Agilent Technologies, Inc. $49.5B 34.0× 26.3× +8.06% (above 0%: growing) +8.47% (above 0%: growing) +69.50% (above 0%: growing) 55.48% 23.64% Compare
IQV IQVIA Holdings Inc. $44.6B 32.8× 22.3× +8.74% (above 0%: growing) −0.65% (below 0%: shrinking) +23.29% (above 0%: growing) 32.85% 11.58% Compare
WAT Waters Corporation $43.6B 109× 44.3× +113.36% (above 0%: growing) n/m +750.00% (above 0%: growing) 44.62% (5.23%) Compare
IDXX IDEXX Laboratories, Inc. $43.1B 39.1× 38.3× +9.66% (above 0%: growing) +17.21% (above 0%: growing) +111.44% (above 0%: growing) 64.04% 34.98% Compare
ILMN Illumina, Inc. $40.5B 48.4× 34.7× +9.44% (above 0%: growing) −8.05% (below 0%: shrinking) −18.27% (below 0%: shrinking) 66.44% 21.14%
MTD Mettler-Toledo International, Inc. $32.8B 36.4× 25.5× +4.48% (above 0%: growing) +18.30% (above 0%: growing) +33.01% (above 0%: growing) 63.29% 30.61% Compare
DGX Quest Diagnostics Incorporated $26.4B 24.6× 20.8× +10.21% (above 0%: growing) +14.74% (above 0%: growing) +5.28% (above 0%: growing) 33.75% 15.08% Compare
LH Labcorp Holdings Inc. $26.4B 26.2× 19.0× +5.78% (above 0%: growing) +28.42% (above 0%: growing) −42.01% (below 0%: shrinking) 29.80% 12.10% Compare
Median of peers $43.4B 34.0× 25.5× +9.20% +15.98% +28.15% 50.05% 13.59%

All 52 Diagnostics & Research stocks →

ILMN metrics, ten years each

Illumina, Inc. (ILMN) key facts

  • Concern: Illumina, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $4.3 billion, down 0.66% from fiscal 2024.
  • Illumina, Inc. (ILMN) is a Diagnostics & Research company in the Healthcare sector, listed on Nasdaq.
  • Net income was $850.0 million, or $5.47 per share (basic), a net margin of 19.6%.
  • As of October 16, 2026, ILMN traded at $262.03, a market capitalization of $40.5 billion.
  • At that price the stock trades at 48.4× trailing-twelve-month earnings and 8.8× sales; its P/E is higher than 47% of its own readings over the past ten years.
  • Return on equity was 33.4% and debt-to-equity 0.53.
  • Its Piotroski F-score is 8 out of 9 and its Altman Z-score is 4.39 (safe zone) for fiscal 2025.

Source: company filings (standardised) and stockrow calculations.

Illumina, Inc. (ILMN) Latest News

stockrow.com/ILMN · Data as of Jun 30, 2026 · For information only; not investment advice. · © 2026 stockrow.com