Guardant Health, Inc.

GH Healthcare Diagnostics & Research

Guardant Health, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $982.0 million, up 32.9% from fiscal 2024. In the quarter to June 2026, revenue grew 44.3%, EPS fell 12.5%, free cash flow fell 5.46% and total debt rose 34.7%, each against the same quarter a year earlier. Revenue growth for five consecutive years; insiders bought in the last twelve months.

158.29 7.59 −4.58%
Market cap
$22.3B
P/E
0.0×
Fwd P/E
−43.3×
Dividend yield
—
F-score
5/9
Altman Z
2.02
Beneish M
−2.78
Dividend safety
n/a

Insider Decisions trades per month

Total buys 0.08
Total sells 173.91
Totals in millions of $.
Dec 25 Mar 26 Jun 26 Sep 26
Buy — — — — — — — 1 — — — —
Sell 3 11 2 — 4 2 9 11 1 6 5 1
Insider Ownership 3.09%

Capital & Financial Ratios $m

Market Cap 22,260.00
Revenue 1,183.10
Net Income (453.44)
Free Cash Flow (240.72)
Net Debt 449.47
Current Ratio 4.03 (at or above 1.5: strong)
Debt/Equity (6.74) (negative: negative equity)
P/E ratio 0.00
Fwd P/E (43.30) (negative: loss-making)
P/S ratio 17.78 (above 10: high)
P/B ratio 0.00
Past 5Y EPS Growth —
This Y EPS Growth 1.95%
Next Y EPS Growth 34.56% (at or above 15%: strong)
Next Y revenue growth 38.29% (at or above 10%: strong)
Next 5Y EPS Growth 60.22% (at or above 15%: strong)

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/S against its own 10 years 58.69%
10-year low 10-year high
EV/Sales against its own 10 years 59.19%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2025 Powerpack
2024 Powerpack
2023 Powerpack
2022 Powerpack
2021 Powerpack
2020 Powerpack
2019 Powerpack
2017 Powerpack
predictions special payouts not included in total or ratios

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 1,169 840 1,202 1,053
Receivables 89 110 138 144
Inventory 62 71 86 105
Other — — — —
1,347 1,055 1,466 1,365
2023 2024 2025 Q'26
Payables 52 39 54 94
ST’ Debt — — — —
Other — — — —
206 226 303 339

Compound Annual Growth %

10y 5y 3y
Sales — 27.92% 29.75%
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — 0.00% 0.00%

Revenue $m

Mar Jun Sep Dec Year
’26 302 335 — — —
’25 203 232 265 281 982
’24 168 177 191 202 739
’23 129 137 143 155 564
’22 96 109 117 127 450
’21 79 92 95 108 374
’20 68 66 75 78 287
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (66) (58) — — —
’25 (63) (60) (35) (26) (185)
’24 (30) (94) (51) (65) (240)
’23 (74) (94) (78) (79) (325)
’22 (29) (112) (78) (91) (309)
’21 (16) (63) (53) (77) (209)
’20 (13) (23) (8) (59) (104)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (71) (70) — — —
’25 (67) (66) (46) (54) (233)
’24 (37) (99) (55) (83) (275)
’23 (82) (101) (80) (83) (345)
’22 (51) (135) (100) (101) (387)
’21 (26) (81) (75) (102) (284)
’20 (41) (33) (18) (67) (158)
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 (0.85) (0.90) — — —
’25 (0.77) (0.80) (0.74) (1.00) (3.32)
’24 (0.94) (0.84) (0.88) (0.90) (3.56)
’23 (1.30) (0.67) (0.73) (1.58) (4.28)
’22 (1.21) (2.25) (1.58) (1.36) (6.41)
’21 (1.09) (0.96) (1.06) (0.89) (4.00)
’20 (0.29) (0.57) (0.78) (0.94) (2.60)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1.4
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low — — 27.04 33.70 55.90 85.41 24.63 20.67 15.81 30.97

Analyst estimates 2026–2028

Powerpack
High — — 49.55 112.22 138.65 181.07 102.85 41.06 38.53 112.43
People
People Employees — 348 454 622 864 1,373 1,793 1,779 2,021 2,506
Revenue/emp, $m 0.00 0.14 0.20 0.34 0.33 0.27 0.25 0.32 0.37 0.39
Income, $m
Income, $m Revenue 25 50 91 214 287 374 450 564 739 982
Gross margin, % 12.38 36.56 52.33 67.01 67.73 67.11 65.23 59.74 60.79 64.46
EBT (46) (83) (84) (70) (246) (384) (653) (479) (435) (418)
EBT margin, % (182.71) (166.96) (92.92) (32.52) (85.76) (102.89) (145.36) (84.90) (58.87) (42.52)
Net income (46) (83) (84) (68) (246) (385) (655) (479) (436) (416)
Depreciation 4 6 7 9 25 38 43 29 36 34
Per share, $
Per share, $ Revenue 1.93 3.96 2.98 2.37 2.94 3.69 4.40 5.04 6.02 7.83
Earnings (3.53) (6.61) (2.80) (0.84) (2.60) (4.00) (6.41) (4.28) (3.56) (3.32)
Cash flow (2.81) (5.74) (2.37) (0.52) (1.07) (2.06) (3.03) (2.90) (1.95) (1.47)
Capex (0.14) (0.53) (0.66) (0.23) (0.55) (0.74) (0.76) (0.18) (0.29) (0.39)
Free cash flow (2.95) (6.27) (3.04) (0.75) (1.62) (2.80) (3.79) (3.08) (2.24) (1.86)
Book value 0.00 24.53 15.89 8.81 13.32 6.37 0.59 1.42 (1.14) (0.79)
Shares, m 13 13 30 91 98 101 102 112 123 125
Valuation, ×
Valuation, × P/E 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
P/S 5.88 5.88 12.61 33.02 43.83 27.12 6.14 5.26 5.07 13.04
P/B 0.00 0.00 2.37 8.87 9.68 15.71 45.84 18.71 0.00 0.00
EV/Sales 1.94 1.94 7.99 30.77 40.38 27.66 6.42 5.21 5.48 13.35
EV/FCF (1.60) (1.60) (7.84) (100.17) (73.28) (34.23) (7.13) (8.09) (13.84) (52.23)
Cash, $m
Cash, $m Operating cash flow (37) (72) (72) (47) (104) (209) (309) (325) (240) (185)
Capex (2) (7) (20) (21) (54) (75) (77) (20) (35) (48)
Free cash flow (38) (79) (92) (68) (158) (284) (387) (345) (275) (233)
Balance, $m
Balance, $m Working capital 89 223 422 525 1,822 919 998 1,141 830 1,163
Total debt 17 0 7 40 806 1,135 1,137 1,140 1,143 1,504
Net debt (78) (221) (412) (483) (989) 202 126 (29) 303 302
Shareholders’ equity — 309 483 798 1,298 645 60 159 (140) (99)
Returns, %
Returns, % ROA (26.90) (51.90) (18.29) (9.76) (15.69) (18.13) (34.32) (28.23) (26.67) (23.79)
ROIC 0.00 (54.57) (81.60) (16.31) (51.42) (30.32) (182.59) (271.47) (170.17) (134.56)
ROE 31.71 61.09 (58.31) (11.81) (24.21) (41.75) (185.65) (438.13) (4,584.50) 348.42
Negative figures in brackets.

All 10 years →

Fiscal years to Dec 2025 · latest quarter Jun 2026

Charts ten years each

Guardant Health, Inc. vs peers in Diagnostics & Research (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
ILMN Illumina, Inc. $40.5B 48.4× 34.7× +9.44% (above 0%: growing) −8.05% (below 0%: shrinking) −18.27% (below 0%: shrinking) 66.44% 21.14% Compare
MTD Mettler-Toledo International, Inc. $32.8B 36.4× 25.5× +4.48% (above 0%: growing) +18.30% (above 0%: growing) +33.01% (above 0%: growing) 63.29% 30.61% Compare
DGX Quest Diagnostics Incorporated $26.4B 24.6× 20.8× +10.21% (above 0%: growing) +14.74% (above 0%: growing) +5.28% (above 0%: growing) 33.75% 15.08% Compare
LH Labcorp Holdings Inc. $26.4B 26.2× 19.0× +5.78% (above 0%: growing) +28.42% (above 0%: growing) −42.01% (below 0%: shrinking) 29.80% 12.10% Compare
GH Guardant Health, Inc. $22.3B — (loss-making) — (loss-making) +44.33% (above 0%: growing) n/m −5.46% (below 0%: shrinking) 65.39% (38.55%)
MEDP Medpace Holdings, Inc. $17.6B 35.6× 26.7× +17.24% (above 0%: growing) +36.39% (above 0%: growing) −3.03% (below 0%: shrinking) 71.36% 20.76% Compare
RVTY Revvity Inc. $17.3B 72.7× 37.5× +1.31% (above 0%: growing) +2.17% (above 0%: growing) +59.29% (above 0%: growing) 57.13% 12.24% Compare
CRL Charles River Laboratories International, Inc. $14.6B — (loss-making) 29.6× −2.72% (below 0%: shrinking) n/m −12.22% (below 0%: shrinking) 36.19% 11.94% Compare
ICLR ICON PLC $13.5B 254× 23.8× +1.20% (above 0%: growing) −59.31% (below 0%: shrinking) +109.66% (above 0%: growing) 23.23% 6.68% Compare
Median of peers $22.0B 36.4× 26.1× +5.13% +14.74% +1.13% 46.66% 13.66%

All 52 Diagnostics & Research stocks →

Guardant Health, Inc. (GH) key facts

  • Strength: Guardant Health, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $982.0 million, up 32.9% from fiscal 2024.
  • Guardant Health, Inc. (GH) is a Diagnostics & Research company in the Healthcare sector, listed on Nasdaq.
  • As of October 16, 2026, GH traded at $158.29, a market capitalization of $22.3 billion.
  • Return on equity was 348.4% and debt-to-equity -6.74.
  • Its Piotroski F-score is 5 out of 9 and its Altman Z-score is 2.02 (grey zone) for fiscal 2025.

Source: company filings (standardised) and stockrow calculations.

Guardant Health, Inc. (GH) Latest News

stockrow.com/GH · Data as of Jun 30, 2026 · For information only; not investment advice. · © 2026 stockrow.com