Saturday 17 October 2026
Export CYTK’s income statement to Excel — free account
Cytokinetics, Incorporated
CYTK Healthcare Biotechnology
Cytokinetics, Incorporated’s revenue for fiscal 2025 (year ended December 2025) was $88.0 million, up 376.6% from fiscal 2024. In the quarter to June 2026, revenue fell 57.1%, EPS fell 33.9%, free cash flow fell 24.0% and total debt rose 57.7%, each against the same quarter a year earlier.
61.95
1.97
−3.08%
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Target Price Range
Analyst price targets
Free accountTen years at a glance Fiscal years to December
| Group | Line | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Trend | 2026e | 2027e | 2028e |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Price, $ | |||||||||||||||
| Price, $ | Low | 6.00 | 7.00 | 5.90 | 5.75 | 8.00 | 17.72 | 29.26 | 25.98 | 45.66 | 29.31 |
Analyst estimates 2026–2028 Powerpack |
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| High | 12.98 | 17.20 | 10.26 | 14.94 | 30.14 | 47.90 | 55.80 | 87.58 | 110.25 | 70.98 | |||||
| People | |||||||||||||||
| People | Employees | 127 | 137 | 130 | 156 | 184 | 253 | 409 | 423 | 498 | 673 | ||||
| Revenue/emp, $m | 0.84 | 0.10 | 0.24 | 0.17 | 0.30 | 0.28 | 0.23 | 0.02 | 0.04 | 0.13 | |||||
| Income, $m | |||||||||||||||
| Income, $m | Revenue | 106 | 13 | 32 | 27 | 56 | 70 | 95 | 8 | 18 | 88 | ||||
| Gross margin, % | 100.00 | 100.00 | 100.00 | 100.00 | 100.00 | 100.00 | 100.00 | 100.00 | 100.00 | 100.00 | |||||
| EBT | 16 | (128) | (106) | (122) | (127) | (215) | (389) | (526) | (590) | (785) | |||||
| EBT margin, % | 15.46 | (955.94) | (337.41) | (452.93) | (228.00) | (305.72) | (411.21) | (6,988.63) | (3,191.11) | (891.60) | |||||
| Net income | 16 | (128) | (106) | (122) | (127) | (215) | (389) | (526) | (590) | (785) | |||||
| Depreciation | 1 | 2 | 1 | 1 | 2 | 2 | 6 | 12 | 10 | 10 | |||||
| Per share, $ | |||||||||||||||
| Per share, $ | Revenue | 2.66 | 0.27 | 0.58 | 0.47 | 0.87 | 0.92 | 1.05 | 0.08 | 0.17 | 0.73 | ||||
| Earnings | 0.41 | (2.59) | (1.95) | (2.11) | (1.97) | (2.80) | (4.33) | (5.45) | (5.26) | (6.54) | |||||
| Cash flow | 0.93 | (2.06) | (1.86) | (1.58) | 0.14 | (1.85) | (3.33) | (4.29) | (3.54) | (4.25) | |||||
| Capex | (0.04) | (0.06) | (0.02) | (0.05) | (0.17) | (0.64) | (0.13) | (0.01) | (0.03) | (0.21) | |||||
| Free cash flow | 0.89 | (2.12) | (1.88) | (1.62) | (0.03) | (2.49) | (3.46) | (4.31) | (3.57) | (4.45) | |||||
| Book value | 2.36 | 2.22 | 0.48 | (0.19) | 1.76 | 3.17 | (1.20) | (4.00) | (1.21) | (5.49) | |||||
| Shares, m | 40 | 49 | 54 | 58 | 65 | 77 | 90 | 97 | 112 | 120 | |||||
| Valuation, × | |||||||||||||||
| Valuation, × | P/E | 32.63 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | ||||
| P/S | 4.65 | 32.34 | 10.92 | 22.74 | 24.02 | 49.76 | 42.12 | 1,078.30 | 285.13 | 86.68 | |||||
| P/B | 5.25 | 3.94 | 13.26 | 0.00 | 11.83 | 14.37 | 0.00 | 0.00 | 0.00 | 0.00 | |||||
| EV/Sales | 3.47 | 15.34 | 5.96 | 19.34 | 18.19 | 45.30 | 40.30 | 1,078.65 | 262.46 | 89.80 | |||||
| EV/FCF | 10.42 | (1.96) | (1.84) | (5.56) | (481.39) | (16.67) | (12.26) | (19.54) | (12.13) | (14.78) | |||||
| Cash, $m | |||||||||||||||
| Cash, $m | Operating cash flow | 37 | (102) | (101) | (91) | 9 | (143) | (300) | (414) | (396) | (510) | ||||
| Capex | (2) | (3) | (1) | (3) | (11) | (49) | (11) | (1) | (4) | (25) | |||||
| Free cash flow | 35 | (105) | (102) | (94) | (2) | (191) | (311) | (416) | (400) | (535) | |||||
| Balance, $m | |||||||||||||||
| Balance, $m | Working capital | 125 | 242 | 185 | 208 | 443 | 464 | 711 | 525 | 928 | 715 | ||||
| Total debt | 30 | 32 | 42 | 134 | 139 | 158 | 611 | 617 | 657 | 1,157 | |||||
| Net debt | (126) | (237) | (156) | (91) | (325) | (314) | (172) | 3 | (419) | 275 | |||||
| Shareholders’ equity | 94 | 110 | 26 | (11) | 113 | 244 | (108) | (386) | (135) | (660) | |||||
| Returns, % | |||||||||||||||
| Returns, % | ROA | 11.53 | (54.97) | (42.01) | (48.58) | (30.91) | (31.32) | (41.91) | (57.23) | (52.97) | (55.55) | ||||
| ROIC | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |||||
| ROE | 20.19 | (125.16) | (156.57) | (1,622.88) | (248.50) | (120.54) | (572.15) | 212.96 | 226.00 | 197.47 | |||||
Negative figures in brackets.
Fiscal years to Dec 2025 · latest quarter Jun 2026
Charts ten years each
Cytokinetics, Incorporated vs peers in Biotechnology (Q) = latest quarter vs a year earlier
| Company | Market cap | P/E | Fwd P/E | Revenue growth (Q) | EPS growth (Q) | FCF growth (Q) | Gross margin (Q) | EBIT margin (Q) | Compare |
|---|---|---|---|---|---|---|---|---|---|
| KRYS Krystal Biotech, Inc. | $9.8B | 38.3× | 38.6× | +24.14% (above 0%: growing) | +39.10% (above 0%: growing) | +40.14% (above 0%: growing) | 94.60% | 49.00% | Compare |
| KYMR Kymera Therapeutics, Inc. | $9.0B | — (loss-making) | — (loss-making) | +466.40% (above 0%: growing) | n/m | +9.97% (above 0%: growing) | 100.00% | (116.32%) | Compare |
| CAI Caris Life Sciences,�Inc. | $9.0B | 81.3× | 163× | +45.38% (above 0%: growing) | n/m | +8.47% (above 0%: growing) | 68.10% | 10.21% | Compare |
| CYTK Cytokinetics, Incorporated | $8.9B | — (loss-making) | — (loss-making) | −57.13% (below 0%: shrinking) | n/m | −24.02% (below 0%: shrinking) | 80.46% | (625.95%) | |
| PTGX Protagonist Therapeutics, Inc. | $8.8B | 106× | 25.0× | +3,749.17% (above 0%: growing) | n/m | +839.65% (above 0%: growing) | 100.00% | 74.37% | Compare |
| TGTX TG Therapeutics, Inc. | $8.6B | 17.8× | 29.4× | +70.27% (above 0%: growing) | −73.68% (below 0%: shrinking) | +427.05% (above 0%: growing) | 82.86% | 9.02% | Compare |
| AXSM Axsome Therapeutics, Inc. | $8.5B | — (loss-making) | — (loss-making) | +45.54% (above 0%: growing) | n/m | −2.98% (below 0%: shrinking) | 93.79% | (22.73%) | Compare |
| ARWR Arrowhead Pharmaceuticals, Inc. | $8.3B | — (loss-making) | — (loss-making) | +171.02% (above 0%: growing) | n/m | −15.43% (below 0%: shrinking) | 100.00% | (226.03%) | Compare |
| ABVX Abivax SA Sponsored ADR | $8.1B | — (loss-making) | — | — | n/m | −48.28% (below 0%: shrinking) | 0.00% | 0.00% | Compare |
| Median of peers | $8.7B | 59.8× | 34.0× | +70.27% | — | +9.22% | 94.20% | 4.51% |
Cytokinetics, Incorporated (CYTK) key facts
- Concern: Cytokinetics, Incorporated reported a net loss of $785.0 million, or a loss of $6.54 per share, for fiscal 2025.
- Strength: Cytokinetics, Incorporated’s revenue for fiscal 2025 (year ended December 2025) was $88.0 million, up 376.6% from fiscal 2024.
- Cytokinetics, Incorporated (CYTK) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
- As of October 16, 2026, CYTK traded at $61.95, a market capitalization of $8.9 billion.
- Trailing earnings are negative, so a P/E ratio is not meaningful; the stock trades at 121× sales.
- Return on equity was 197.5% and debt-to-equity -6.61.
- Its Piotroski F-score is 2 out of 9 and its Altman Z-score is −1.98 (distress zone) for fiscal 2025.