Cytokinetics, Incorporated

CYTK Healthcare Biotechnology

Cytokinetics, Incorporated’s revenue for fiscal 2025 (year ended December 2025) was $88.0 million, up 376.6% from fiscal 2024. In the quarter to June 2026, revenue fell 57.1%, EPS fell 33.9%, free cash flow fell 24.0% and total debt rose 57.7%, each against the same quarter a year earlier.

61.95 1.97 −3.08%
Market cap
$8.9B
P/E
0.0×
Fwd P/E
−11.1×
Dividend yield
—
F-score
2/9
Altman Z
−1.98
Beneish M
−0.44
Dividend safety
n/a

Insider Decisions trades per month

Total sells 50.62
Totals in millions of $.
Dec 25 Mar 26 Jun 26 Sep 26
Buy — — — — — — — — — — — —
Sell 4 9 2 2 11 7 9 8 8 4 7 2
Insider Ownership 0.00%

Capital & Financial Ratios $m

Market Cap 8,890.00
Revenue 67.67
Net Income (894.00)
Free Cash Flow (580.71)
Net Debt (18.60)
Current Ratio 6.66 (at or above 1.5: strong)
Debt/Equity (6.61) (negative: negative equity)
P/E ratio 0.00
Fwd P/E (11.10) (negative: loss-making)
P/S ratio 120.92 (above 10: high)
P/B ratio 0.00
Past 5Y EPS Growth —
This Y EPS Growth 7.73%
Next Y EPS Growth 25.03% (at or above 15%: strong)
Next Y revenue growth 71.06% (at or above 10%: strong)
Next 5Y EPS Growth 31.75% (at or above 15%: strong)

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/S against its own 10 years 76.52%
10-year low 10-year high
EV/Sales against its own 10 years 77.29%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2025 Powerpack
2024 Powerpack
2023 Powerpack
2022 Powerpack
2021 Powerpack
2020 Powerpack
2019 Powerpack
2017 Powerpack
predictions special payouts not included in total or ratios

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 615 1,076 882 1,166
Receivables 1 17 18 24
Inventory — — — 0
Other — — — —
628 1,108 917 1,208
2023 2024 2025 Q'26
Payables 22 20 22 21
ST’ Debt 10 12 41 27
Other 11 21 35 34
103 180 202 181

Compound Annual Growth %

10y 5y 3y
Sales 11.88% 9.54% (2.36%)
Cash Flow 0.00% 0.00% 0.00%
Earnings 0.00% 0.00% 0.00%
Book Value 0.00% 0.00% 0.00%

Revenue $m

Mar Jun Sep Dec Year
’26 19 29 — — —
’25 2 67 2 18 88
’24 1 0 0 17 18
’23 5 1 0 2 8
’22 1 89 3 2 95
’21 7 3 5 56 70
’20 4 4 42 7 56
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (145) (160) — — —
’25 (132) (128) (108) (143) (510)
’24 (130) (99) (101) (66) (396)
’23 (122) (122) (96) (74) (414)
’22 (27) (90) (84) (98) (300)
’21 (30) (29) (39) (45) (143)
’20 (30) (27) 14 52 9
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (151) (164) — — —
’25 (137) (132) (117) (148) (535)
’24 (130) (101) (102) (67) (400)
’23 (123) (123) (96) (74) (416)
’22 (28) (91) (90) (101) (311)
’21 (36) (38) (54) (62) (191)
’20 (31) (28) 12 46 (2)
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 (1.67) (1.50) — — —
’25 (1.36) (1.12) (2.55) (1.50) (6.54)
’24 (1.33) (1.31) (1.36) (1.26) (5.26)
’23 (1.38) (1.34) (1.35) (1.38) (5.45)
’22 (1.05) (0.23) (1.52) (1.45) (4.33)
’21 (0.66) (0.86) (0.95) (0.36) (2.80)
’20 (0.66) (0.68) (0.05) (0.62) (1.97)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1.2
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low 6.00 7.00 5.90 5.75 8.00 17.72 29.26 25.98 45.66 29.31

Analyst estimates 2026–2028

Powerpack
High 12.98 17.20 10.26 14.94 30.14 47.90 55.80 87.58 110.25 70.98
People
People Employees 127 137 130 156 184 253 409 423 498 673
Revenue/emp, $m 0.84 0.10 0.24 0.17 0.30 0.28 0.23 0.02 0.04 0.13
Income, $m
Income, $m Revenue 106 13 32 27 56 70 95 8 18 88
Gross margin, % 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00
EBT 16 (128) (106) (122) (127) (215) (389) (526) (590) (785)
EBT margin, % 15.46 (955.94) (337.41) (452.93) (228.00) (305.72) (411.21) (6,988.63) (3,191.11) (891.60)
Net income 16 (128) (106) (122) (127) (215) (389) (526) (590) (785)
Depreciation 1 2 1 1 2 2 6 12 10 10
Per share, $
Per share, $ Revenue 2.66 0.27 0.58 0.47 0.87 0.92 1.05 0.08 0.17 0.73
Earnings 0.41 (2.59) (1.95) (2.11) (1.97) (2.80) (4.33) (5.45) (5.26) (6.54)
Cash flow 0.93 (2.06) (1.86) (1.58) 0.14 (1.85) (3.33) (4.29) (3.54) (4.25)
Capex (0.04) (0.06) (0.02) (0.05) (0.17) (0.64) (0.13) (0.01) (0.03) (0.21)
Free cash flow 0.89 (2.12) (1.88) (1.62) (0.03) (2.49) (3.46) (4.31) (3.57) (4.45)
Book value 2.36 2.22 0.48 (0.19) 1.76 3.17 (1.20) (4.00) (1.21) (5.49)
Shares, m 40 49 54 58 65 77 90 97 112 120
Valuation, ×
Valuation, × P/E 32.63 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
P/S 4.65 32.34 10.92 22.74 24.02 49.76 42.12 1,078.30 285.13 86.68
P/B 5.25 3.94 13.26 0.00 11.83 14.37 0.00 0.00 0.00 0.00
EV/Sales 3.47 15.34 5.96 19.34 18.19 45.30 40.30 1,078.65 262.46 89.80
EV/FCF 10.42 (1.96) (1.84) (5.56) (481.39) (16.67) (12.26) (19.54) (12.13) (14.78)
Cash, $m
Cash, $m Operating cash flow 37 (102) (101) (91) 9 (143) (300) (414) (396) (510)
Capex (2) (3) (1) (3) (11) (49) (11) (1) (4) (25)
Free cash flow 35 (105) (102) (94) (2) (191) (311) (416) (400) (535)
Balance, $m
Balance, $m Working capital 125 242 185 208 443 464 711 525 928 715
Total debt 30 32 42 134 139 158 611 617 657 1,157
Net debt (126) (237) (156) (91) (325) (314) (172) 3 (419) 275
Shareholders’ equity 94 110 26 (11) 113 244 (108) (386) (135) (660)
Returns, %
Returns, % ROA 11.53 (54.97) (42.01) (48.58) (30.91) (31.32) (41.91) (57.23) (52.97) (55.55)
ROIC 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
ROE 20.19 (125.16) (156.57) (1,622.88) (248.50) (120.54) (572.15) 212.96 226.00 197.47
Negative figures in brackets.

All 10 years →

Fiscal years to Dec 2025 · latest quarter Jun 2026

Charts ten years each

Cytokinetics, Incorporated vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
KRYS Krystal Biotech, Inc. $9.8B 38.3× 38.6× +24.14% (above 0%: growing) +39.10% (above 0%: growing) +40.14% (above 0%: growing) 94.60% 49.00% Compare
KYMR Kymera Therapeutics, Inc. $9.0B — (loss-making) — (loss-making) +466.40% (above 0%: growing) n/m +9.97% (above 0%: growing) 100.00% (116.32%) Compare
CAI Caris Life Sciences,�Inc. $9.0B 81.3× 163× +45.38% (above 0%: growing) n/m +8.47% (above 0%: growing) 68.10% 10.21% Compare
CYTK Cytokinetics, Incorporated $8.9B — (loss-making) — (loss-making) −57.13% (below 0%: shrinking) n/m −24.02% (below 0%: shrinking) 80.46% (625.95%)
PTGX Protagonist Therapeutics, Inc. $8.8B 106× 25.0× +3,749.17% (above 0%: growing) n/m +839.65% (above 0%: growing) 100.00% 74.37% Compare
TGTX TG Therapeutics, Inc. $8.6B 17.8× 29.4× +70.27% (above 0%: growing) −73.68% (below 0%: shrinking) +427.05% (above 0%: growing) 82.86% 9.02% Compare
AXSM Axsome Therapeutics, Inc. $8.5B — (loss-making) — (loss-making) +45.54% (above 0%: growing) n/m −2.98% (below 0%: shrinking) 93.79% (22.73%) Compare
ARWR Arrowhead Pharmaceuticals, Inc. $8.3B — (loss-making) — (loss-making) +171.02% (above 0%: growing) n/m −15.43% (below 0%: shrinking) 100.00% (226.03%) Compare
ABVX Abivax SA Sponsored ADR $8.1B — (loss-making) — — n/m −48.28% (below 0%: shrinking) 0.00% 0.00% Compare
Median of peers $8.7B 59.8× 34.0× +70.27% — +9.22% 94.20% 4.51%

All 614 Biotechnology stocks →

Cytokinetics, Incorporated (CYTK) key facts

  • Concern: Cytokinetics, Incorporated reported a net loss of $785.0 million, or a loss of $6.54 per share, for fiscal 2025.
  • Strength: Cytokinetics, Incorporated’s revenue for fiscal 2025 (year ended December 2025) was $88.0 million, up 376.6% from fiscal 2024.
  • Cytokinetics, Incorporated (CYTK) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • As of October 16, 2026, CYTK traded at $61.95, a market capitalization of $8.9 billion.
  • Trailing earnings are negative, so a P/E ratio is not meaningful; the stock trades at 121× sales.
  • Return on equity was 197.5% and debt-to-equity -6.61.
  • Its Piotroski F-score is 2 out of 9 and its Altman Z-score is −1.98 (distress zone) for fiscal 2025.

Source: company filings (standardised) and stockrow calculations.

Cytokinetics, Incorporated (CYTK) Latest News

13 Aug

stockrow.com/CYTK · Data as of Jun 30, 2026 · For information only; not investment advice. · © 2026 stockrow.com