Castle Biosciences, Inc.

CSTL Healthcare Diagnostics & Research

Castle Biosciences, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $344.2 million, up 3.66% from fiscal 2024.

Revenue
+23.9%
EPS
−550.0%
Free cash flow
+56.8%
Total debt
−59.9%

Quarter to September 2026, against a year earlier

32.06 2.14 −6.26%
Market cap
$1.0B
P/E
0.0×
Fwd P/E
−29.8×
Dividend yield
—
F-score
3/9
Altman Z
6.70
Beneish M
−3.49
Dividend safety
n/a

Castle Biosciences, Inc. (CSTL) EV/Sales

Alert me on EV/Sales

As of 5 November 2026, Castle Biosciences, Inc. (CSTL) trades at a EV/Sales of 2.1×. Over the past ten years it has ranged from 0.5× (August 2025) to 23.2× (February 2021); the current reading is higher than 44% of that period. That is below the Diagnostics & Research industry median of 5.2× and below the Healthcare sector median of 3.5×.

EV/Sales, daily

Embed this chart

Annual newest first

Period EV/Sales Change
FY2025 2.4× 76.82%
FY2024 1.4× (15.90%)
FY2023 1.6× (35.54%)
FY2022 2.5× (68.38%)
FY2021 8.0× (43.03%)
FY2020 14.1× 230.57%
FY2019 4.3× 117.34%
FY2018 2.0× 0.00%
FY2017 2.0× —

Quarterly newest first

Period EV/Sales Change
Sep 2026 2.2× 68.47%
Jun 2026 1.3× (7.60%)
Mar 2026 1.4× (41.73%)
Dec 2025 2.4× 116.33%
29 more quarters

Against its own ten years

Low 0.5× High 23.2×
Ten-year median 2.4×
Current reading's percentile 44

EV/Sales against peers

Company EV/Sales
FRNM Freenome, Inc compare n/m
MYGN Myriad Genetics, Inc. compare 0.8×
FLGT Fulgent Genetics, Inc. compare 0.8×
CSTL Castle Biosciences, Inc. 2.1×
VCYT Veracyte, Inc. compare 2.5×
OPK OPKO Health, Inc. compare 2.8×
NEO NeoGenomics, Inc. compare 3.3×
WGS GeneDx Holdings Corp. compare 4.2×
PSNL Personalis, Inc. compare 18.6×
Diagnostics & Research industry median 5.2×
Healthcare sector median 3.5×
Market median 2.1×

What EV/Sales is

EV/Sales tells an investor how the value of a whole company, counting its debt and cash, compares with the sales it brings in.

((Stock Price × Shares (Basic, Weighted) (latest quarter)) + (Long Term Debt (Total) (latest quarter) + Current Part of Debt (latest quarter)) − Cash & Short Term Investments (latest quarter)) ÷ Revenue (TTM)

The full definition of EV/Sales →

More on CSTL