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Castle Biosciences, Inc. (CSTL) vs GeneDx Holdings Corp. (WGS)

Castle Biosciences, Inc. and GeneDx Holdings Corp. are both Diagnostics & Research companies. GeneDx Holdings Corp. is the larger, with a market value of $1.9B against $1.0B — 1.8× the size. GeneDx Holdings Corp. grew revenue faster over the last twelve months: 25.4% against 9.78%. Castle Biosciences, Inc. has the higher net margin (−6.10% vs −23.4%) and the higher return on invested capital (−3.63% vs −27.7%). Across the 18 metrics below, Castle Biosciences, Inc. leads on 15 and GeneDx Holdings Corp. on 3.

Valuation

Metric CSTL WGS Diagnostics & Research median
P/E n/m n/m 34.52
P/S 2.77 4.24 4.24
P/B 2.19 7.89 3.42
Price to free cash flow 262.33 n/m 33.51
EV/EBITDA n/m n/m 23.44
EV/Sales 2.10 4.16 5.18
Earnings yield (2.25%) (5.61%) (1.50%)
Free cash flow yield 0.38% (3.93%) 0.00%

Profitability

Metric CSTL WGS Diagnostics & Research median
Gross margin 77.07% 69.37% 48.32%
Operating margin (7.43%) (20.34%) (5.68%)
Net margin (6.10%) (23.40%) (4.10%)
Free cash flow margin 1.06% (16.68%) 0.00%
Return on equity (4.87%) (40.80%) 0.00%
Return on assets (4.03%) (22.50%) (6.05%)
Return on invested capital (3.63%) (27.70%) 0.00%

Growth

Metric CSTL WGS Diagnostics & Research median
Revenue growth (TTM) 9.78% 25.42% 8.99%
EPS growth (last fiscal year) (233.87%) 62.37% 20.36%
Revenue growth, 5-year CAGR 40.60% 18.98% 7.30%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric CSTL WGS Diagnostics & Research median
Debt to equity 0.01 0.40 0.01
Current ratio 5.28 3.30 2.27
Net debt to EBITDA 46.20 (10.13) 0.68

Dividend

Metric CSTL WGS Diagnostics & Research median
Dividend yield — — 0.67%
Payout ratio — — 0.20

Size

Metric CSTL WGS Diagnostics & Research median
Market cap 1.04b 1.92b 2.22b

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