Castle Biosciences, Inc. (CSTL) vs GeneDx Holdings Corp. (WGS)

Castle Biosciences, Inc. and GeneDx Holdings Corp. are both Diagnostics & Research companies. GeneDx Holdings Corp. is the larger, with a market value of $2.6B against $1.1B — 2.4× the size. GeneDx Holdings Corp. grew revenue faster over the last twelve months: 25.4% against 3.18%. Castle Biosciences, Inc. has the higher net margin (−5.43% vs −23.4%) and the higher return on invested capital (−9.40% vs −27.7%). Across the 18 metrics below, Castle Biosciences, Inc. leads on 15 and GeneDx Holdings Corp. on 3.

Valuation

Metric CSTL WGS Diagnostics & Research median
P/E n/m n/m 33.95
P/S 3.03 5.78 4.87
P/B 2.30 10.75 3.12
Price to free cash flow n/m n/m 34.02
EV/EBITDA n/m n/m 25.20
EV/Sales 2.31 5.70 5.66
Earnings yield (1.85%) (4.12%) (1.75%)
Free cash flow yield (0.04%) (2.89%) (0.13%)

Profitability

Metric CSTL WGS Diagnostics & Research median
Gross margin 77.26% 69.37% 50.89%
Operating margin (8.99%) (20.34%) (8.57%)
Net margin (5.43%) (23.40%) (6.37%)
Free cash flow margin (0.13%) (16.68%) 0.00%
Return on equity (4.20%) (40.80%) (2.92%)
Return on assets (3.51%) (22.50%) (6.71%)
Return on invested capital (9.40%) (27.70%) 0.00%

Growth

Metric CSTL WGS Diagnostics & Research median
Revenue growth (TTM) 3.18% 25.42% 7.69%
EPS growth (last fiscal year) (233.87%) 62.37% —
Revenue growth, 5-year CAGR 40.60% 18.98% 7.40%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric CSTL WGS Diagnostics & Research median
Debt to equity 0.02 0.40 0.11
Current ratio 6.04 3.30 2.02
Net debt to EBITDA 46.20 (10.13) 0.78

Dividend

Metric CSTL WGS Diagnostics & Research median
Dividend yield — — 0.70%
Payout ratio 0.00 0.00 0.00

Size

Metric CSTL WGS Diagnostics & Research median
Market cap 1.08b 2.61b 2.56b

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