Castle Biosciences, Inc. (CSTL) vs Personalis, Inc. (PSNL)

Castle Biosciences, Inc. and Personalis, Inc. are both Diagnostics & Research companies. Personalis, Inc. is the larger, with a market value of $1.7B against $1.0B — 1.7× the size. Castle Biosciences, Inc. grew revenue faster over the last twelve months: 3.18% against −13.3%. Castle Biosciences, Inc. has the higher net margin (−5.43% vs −153.8%) and the higher return on invested capital (−9.40% vs −317.5%). Across the 18 metrics below, Castle Biosciences, Inc. leads on 15 and Personalis, Inc. on 3.

Valuation

Metric CSTL PSNL Diagnostics & Research median
P/E n/m n/m 35.56
P/S 2.72 23.68 4.37
P/B 2.07 7.02 3.06
Price to free cash flow n/m n/m 35.76
EV/EBITDA n/m n/m 24.35
EV/Sales 2.00 20.89 5.51
Earnings yield (2.07%) (6.96%) (1.89%)
Free cash flow yield (0.05%) (6.11%) (0.15%)

Profitability

Metric CSTL PSNL Diagnostics & Research median
Gross margin 77.26% 12.69% 50.89%
Operating margin (8.99%) (164.07%) (8.57%)
Net margin (5.43%) (153.84%) (6.37%)
Free cash flow margin (0.13%) (144.76%) 0.00%
Return on equity (4.20%) (50.32%) (2.92%)
Return on assets (3.51%) (37.55%) (6.71%)
Return on invested capital (9.40%) (317.48%) 0.00%

Growth

Metric CSTL PSNL Diagnostics & Research median
Revenue growth (TTM) 3.18% (13.26%) 7.69%
EPS growth (last fiscal year) (233.87%) 33.58% 25.92%
Revenue growth, 5-year CAGR 40.60% (2.40%) 7.40%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric CSTL PSNL Diagnostics & Research median
Debt to equity 0.02 0.00 0.11
Current ratio 6.04 5.28 2.02
Net debt to EBITDA 46.20 2.93 0.70

Dividend

Metric CSTL PSNL Diagnostics & Research median
Dividend yield — — 0.66%
Payout ratio — — 0.20

Size

Metric CSTL PSNL Diagnostics & Research median
Market cap 1.03b 1.70b 2.16b

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