Castle Biosciences, Inc. (CSTL) vs Personalis, Inc. (PSNL)

Castle Biosciences, Inc. and Personalis, Inc. are both Diagnostics & Research companies. Personalis, Inc. is the larger, with a market value of $1.7B against $1.0B — 1.6× the size. Personalis, Inc. grew revenue faster over the last twelve months: 16.9% against 9.78%. Castle Biosciences, Inc. has the higher net margin (−6.10% vs −147.7%) and the higher return on invested capital (−3.63% vs −358.4%). Across the 18 metrics below, Castle Biosciences, Inc. leads on 14 and Personalis, Inc. on 4.

Valuation

Metric CSTL PSNL Diagnostics & Research median
P/E n/m n/m 35.23
P/S 2.65 20.98 4.08
P/B 2.09 7.97 3.45
Price to free cash flow 250.73 n/m 33.72
EV/EBITDA n/m n/m 25.01
EV/Sales 1.98 18.85 5.20
Earnings yield (2.36%) (7.40%) (1.47%)
Free cash flow yield 0.40% (6.26%) 0.00%

Profitability

Metric CSTL PSNL Diagnostics & Research median
Gross margin 77.07% 16.71% 48.32%
Operating margin (7.43%) (156.66%) (5.68%)
Net margin (6.10%) (147.74%) (4.10%)
Free cash flow margin 1.06% (120.79%) 0.00%
Return on equity (4.87%) (62.14%) 0.00%
Return on assets (4.03%) (44.66%) (6.05%)
Return on invested capital (3.63%) (358.37%) 0.00%

Growth

Metric CSTL PSNL Diagnostics & Research median
Revenue growth (TTM) 9.78% 16.88% 9.15%
EPS growth (last fiscal year) (233.87%) 33.58% 20.36%
Revenue growth, 5-year CAGR 40.60% (2.40%) 7.30%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric CSTL PSNL Diagnostics & Research median
Debt to equity 0.01 0.00 0.04
Current ratio 5.28 4.53 2.27
Net debt to EBITDA 46.20 2.93 0.68

Dividend

Metric CSTL PSNL Diagnostics & Research median
Dividend yield — — 0.66%
Payout ratio — — 0.20

Size

Metric CSTL PSNL Diagnostics & Research median
Market cap 1.04b 1.69b 1.93b

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