Castle Biosciences, Inc. (CSTL) vs OPKO Health, Inc. (OPK)

Castle Biosciences, Inc. and OPKO Health, Inc. are both Diagnostics & Research companies. OPKO Health, Inc. is the larger, with a market value of $1.2B against $1.1B — 1.1× the size. Castle Biosciences, Inc. grew revenue faster over the last twelve months: 3.18% against −11.5%. Castle Biosciences, Inc. has the higher net margin (−5.43% vs −12.4%) and the lower return on invested capital (−9.40% vs −2.45%). Across the 18 metrics below, Castle Biosciences, Inc. leads on 12 and OPKO Health, Inc. on 6.

Valuation

Metric CSTL OPK Diagnostics & Research median
P/E n/m n/m 33.95
P/S 3.03 2.11 4.87
P/B 2.30 1.05 3.12
Price to free cash flow n/m n/m 34.02
EV/EBITDA n/m 30.58 25.20
EV/Sales 2.31 2.19 5.66
Earnings yield (1.85%) (5.49%) (1.75%)
Free cash flow yield (0.04%) (11.60%) (0.13%)

Profitability

Metric CSTL OPK Diagnostics & Research median
Gross margin 77.26% 40.77% 50.89%
Operating margin (8.99%) (8.21%) (8.57%)
Net margin (5.43%) (12.40%) (6.37%)
Free cash flow margin (0.13%) (22.75%) 0.00%
Return on equity (4.20%) (5.88%) (2.92%)
Return on assets (3.51%) (3.83%) (6.71%)
Return on invested capital (9.40%) (2.45%) 0.00%

Growth

Metric CSTL OPK Diagnostics & Research median
Revenue growth (TTM) 3.18% (11.47%) 7.69%
EPS growth (last fiscal year) (233.87%) (275.00%) —
Revenue growth, 5-year CAGR 40.60% (15.82%) 7.40%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric CSTL OPK Diagnostics & Research median
Debt to equity 0.02 0.29 0.11
Current ratio 6.04 3.35 2.02
Net debt to EBITDA 46.20 1.33 0.78

Dividend

Metric CSTL OPK Diagnostics & Research median
Dividend yield — — 0.70%
Payout ratio 0.00 0.00 0.00

Size

Metric CSTL OPK Diagnostics & Research median
Market cap 1.08b 1.22b 2.56b

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