Castle Biosciences, Inc. (CSTL) vs OPKO Health, Inc. (OPK)

Castle Biosciences, Inc. and OPKO Health, Inc. are both Diagnostics & Research companies. OPKO Health, Inc. is the larger, with a market value of $1.3B against $1.0B — 1.3× the size. Castle Biosciences, Inc. grew revenue faster over the last twelve months: 9.78% against −21.9%. Castle Biosciences, Inc. has the higher net margin (−6.10% vs −29.5%) and the higher return on invested capital (−3.63% vs −6.72%). Across the 18 metrics below, Castle Biosciences, Inc. leads on 15 and OPKO Health, Inc. on 3.

Valuation

Metric CSTL OPK Diagnostics & Research median
P/E n/m n/m 34.52
P/S 2.77 2.60 4.24
P/B 2.19 1.17 3.42
Price to free cash flow 262.33 n/m 33.51
EV/EBITDA n/m n/m 23.44
EV/Sales 2.10 2.77 5.18
Earnings yield (2.25%) (10.86%) (1.50%)
Free cash flow yield 0.38% (11.10%) 0.00%

Profitability

Metric CSTL OPK Diagnostics & Research median
Gross margin 77.07% 46.22% 48.32%
Operating margin (7.43%) (25.46%) (5.68%)
Net margin (6.10%) (29.51%) (4.10%)
Free cash flow margin 1.06% (26.91%) 0.00%
Return on equity (4.87%) (12.23%) 0.00%
Return on assets (4.03%) (7.64%) (6.05%)
Return on invested capital (3.63%) (6.72%) 0.00%

Growth

Metric CSTL OPK Diagnostics & Research median
Revenue growth (TTM) 9.78% (21.87%) 8.99%
EPS growth (last fiscal year) (233.87%) (275.00%) 20.36%
Revenue growth, 5-year CAGR 40.60% (15.82%) 7.30%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric CSTL OPK Diagnostics & Research median
Debt to equity 0.01 0.41 0.01
Current ratio 5.28 4.97 2.27
Net debt to EBITDA 46.20 1.33 0.68

Dividend

Metric CSTL OPK Diagnostics & Research median
Dividend yield — — 0.67%
Payout ratio — — 0.20

Size

Metric CSTL OPK Diagnostics & Research median
Market cap 1.04b 1.31b 2.22b

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