C4 Therapeutics, Inc.

CCCC Healthcare Biotechnology

C4 Therapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $35.9 million, up 1.02% from fiscal 2024. In the quarter to June 2026, revenue grew 2.75%, EPS grew 51.4% and free cash flow grew 86.8%, each against the same quarter a year earlier.

2.77 0.01 −0.36%
Market cap
$342.0M
P/E
0.0×
Fwd P/E
−4.1×
Dividend yield
—
F-score
4/9
Altman Z
−2.16
Beneish M
−2.61
Dividend safety
n/a

Insider Decisions trades per month

Total sells 0.02
Totals in millions of $.
Dec 25 Mar 26 Jun 26 Sep 26
Buy — — — — — — — — — — — —
Sell — — 1 — — — — — — — — —
Insider Ownership 13.45%

Capital & Financial Ratios $m

Market Cap 342.01
Revenue 35.04
Net Income (101.42)
Free Cash Flow (85.39)
Net Debt (253.66)
Current Ratio 5.45 (at or above 1.5: strong)
Debt/Equity 0.00 (at or below 0.5: strong)
P/E ratio 0.00
Fwd P/E (4.07) (negative: loss-making)
P/S ratio 10.33 (above 10: high)
P/B ratio 1.46
Past 5Y EPS Growth —
This Y EPS Growth 33.00% (at or above 15%: strong)
Next Y EPS Growth (10.95%) (below 0%: weak)
Next Y revenue growth (26.56%) (below 0%: weak)
Next 5Y EPS Growth 3.09%

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/S against its own 10 years 50.30%
10-year low 10-year high
P/B against its own 10 years 55.88%
10-year low 10-year high
EV/Sales against its own 10 years 34.62%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2025 Powerpack
2024 Powerpack
2023 Powerpack
2022 Powerpack
2021 Powerpack
predictions special payouts not included in total or ratios

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 254 245 249 254
Receivables 12 3 2 1
Inventory — — — —
Other — — — —
271 258 258 263
2023 2024 2025 Q'26
Payables 1 1 1 1
ST’ Debt — — — —
Other — — — —
43 45 33 48

Compound Annual Growth %

10y 5y 3y
Sales — 1.61% 4.95%
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — (1.79%) (3.91%)

Revenue $m

Mar Jun Sep Dec Year
’26 6 7 — — —
’25 7 6 11 11 36
’24 3 12 15 5 36
’23 4 3 11 3 21
’22 8 14 7 3 31
’21 7 10 9 20 46
’20 7 10 8 8 33
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (30) (2) — — —
’25 (33) (12) (31) (22) (99)
’24 (18) (5) (24) (18) (65)
’23 (33) (19) (31) (24) (107)
’22 (27) (22) (28) (29) (106)
’21 (25) (18) (18) (26) (87)
’20 (17) (15) (14) (22) (67)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (30) (2) — — —
’25 (33) (12) (32) (22) (99)
’24 (18) (5) (24) (18) (65)
’23 (34) (19) (31) (24) (109)
’22 (27) (23) (31) (31) (111)
’21 (25) (19) (18) (26) (88)
’20 (17) (14) (15) (22) (68)
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 (0.20) (0.18) — — —
’25 (0.37) (0.37) (0.44) (0.18) (1.27)
’24 (0.41) (0.26) (0.35) (0.49) (1.52)
’23 (0.71) (0.73) (0.55) (0.68) (2.67)
’22 (0.65) (0.56) (0.65) (0.76) (2.62)
’21 (0.49) (0.51) (0.51) (0.31) (1.82)
’20 (8.14) (7.31) (17.55) 23.79 (5.83)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1.1
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low — — — — 22.40 27.84 4.84 1.06 3.43 1.09

Analyst estimates 2026–2028

Powerpack
High — — — — 37.80 51.21 33.76 9.41 11.88 4.26
People
People Employees — — — 88 99 121 146 145 110 104
Revenue/emp, $m — — 0.00 0.24 0.34 0.38 0.21 0.14 0.32 0.35
Income, $m
Income, $m Revenue — — 19 21 33 46 31 21 36 36
Gross margin, % — — 0.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00
EBT — — (16) (33) (67) (84) (128) (131) (105) (105)
EBT margin, % — — (81.14) (155.72) (201.72) (183.23) (412.19) (632.17) (295.60) (291.74)
Net income — 0 (16) (34) (66) (84) (128) (132) (105) (105)
Depreciation — — 4 2 2 4 3 (1) (4) (1)
Per share, $
Per share, $ Revenue — — 0.46 15.58 2.92 0.99 0.64 0.42 0.51 0.43
Earnings — — (0.57) (24.85) (5.83) (1.82) (2.62) (2.67) (1.52) (1.27)
Cash flow — — (0.40) 40.54 (5.91) (1.89) (2.17) (2.15) (0.94) (1.19)
Capex — — 0.00 (0.94) (0.06) (0.03) (0.11) (0.03) 0.00 (0.01)
Free cash flow — — (0.40) 39.60 (5.97) (1.92) (2.28) (2.19) (0.94) (1.20)
Book value — — 0.74 (0.71) 24.70 8.46 5.92 4.96 3.11 3.10
Shares, m — — 42 1 11 46 49 50 69 83
Valuation, ×
Valuation, × P/E — — 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
P/S — — 1.30 1.30 11.35 32.38 10.03 15.59 7.02 4.40
P/B — — 0.00 0.00 1.34 3.81 1.08 1.32 1.16 0.62
EV/Sales — — (4.93) (4.93) 0.48 25.89 1.51 4.28 0.67 (1.98)
EV/FCF — — 2.66 2.66 (0.24) (13.43) (0.42) (0.82) (0.36) 0.72
Cash, $m
Cash, $m Operating cash flow — — (17) 56 (67) (87) (106) (107) (65) (99)
Capex — — (3) (1) (1) (1) (5) (2) 0 (1)
Free cash flow — — (17) 54 (68) (88) (111) (109) (65) (99)
Balance, $m
Balance, $m Working capital — — 100 63 337 274 243 228 213 225
Total debt — — 14 14 11 12 11 — — —
Net debt — — (22) (77) (361) (297) (265) (254) (245) (249)
Shareholders’ equity — — 31 (1) 281 390 289 246 216 257
Returns, %
Returns, % ROA — — (32.91) (32.16) (25.59) (18.50) (27.34) (32.82) (29.01) (29.63)
ROIC — — 0.00 0.00 0.00 (55.54) (329.60) 0.00 0.00 (894.58)
ROE — — 25.15 44.41 (78.58) (25.03) (37.76) (49.50) (45.58) (44.44)
Negative figures in brackets.

All 10 years →

Fiscal years to Dec 2025 · latest quarter Jun 2026

Charts ten years each

C4 Therapeutics, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
AVIR Atea Pharmaceuticals, Inc. $363.3M — (loss-making) — (loss-making) +295.16% (above 0%: growing) n/m +85.53% (above 0%: growing) 0.00% 0.00% Compare
FENC Adherex Technologies Inc. $362.9M — (loss-making) 31.4× +85.18% (above 0%: growing) n/m +101.36% (above 0%: growing) 95.97% 9.72% Compare
TTRX Turn Therapeutics Inc. $345.3M — (loss-making) — — n/m −74.76% (below 0%: shrinking) — 0.00% Compare
OBIO Orchestra BioMed Holdings, Inc. $345.0M — (loss-making) — (loss-making) −89.47% (below 0%: shrinking) n/m −25.87% (below 0%: shrinking) 71.59% (25,404.55%) Compare
CCCC C4 Therapeutics, Inc. $342.0M — (loss-making) — (loss-making) +2.75% (above 0%: growing) n/m +86.84% (above 0%: growing) 100.00% (397.88%)
RLMD Relmada Therapeutics, Inc. $341.3M — (loss-making) — — n/m −50.06% (below 0%: shrinking) 0.00% 0.00% Compare
IRD Opus Genetics, Inc. $336.9M — (loss-making) — (loss-making) −73.80% (below 0%: shrinking) n/m −16.37% (below 0%: shrinking) 100.00% (2,182.78%) Compare
ENTA Enanta Pharmaceuticals, Inc. $334.1M — (loss-making) — (loss-making) −21.60% (below 0%: shrinking) n/m −157.51% (below 0%: shrinking) 100.00% (120.04%) Compare
CYPH Cypherpunk Technologies Inc. $325.5M 4.4× — (loss-making) 0.00% n/m +15.53% (above 0%: growing) 0.00% 0.00% Compare
Median of peers $343.2M — — −10.80% — −21.12% 71.59% 0.00%

All 614 Biotechnology stocks →

C4 Therapeutics, Inc. (CCCC) key facts

  • Strength: C4 Therapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $35.9 million, up 1.02% from fiscal 2024.
  • C4 Therapeutics, Inc. (CCCC) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • As of October 16, 2026, CCCC traded at $2.77, a market capitalization of $342.0 million.
  • Return on equity was −44.4% and debt-to-equity 0.00.
  • Its Piotroski F-score is 4 out of 9 and its Altman Z-score is −2.16 (distress zone) for fiscal 2025.

Source: company filings (standardised) and stockrow calculations.

C4 Therapeutics, Inc. (CCCC) Latest News

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stockrow.com/CCCC · Data as of Jun 30, 2026 · For information only; not investment advice. · © 2026 stockrow.com