Opus Genetics, Inc.

IRD Healthcare Biotechnology

Opus Genetics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $14.2 million, up 29.1% from fiscal 2024.

Revenue
−73.8%
EPS
+33.3%
Free cash flow
−16.4%

Quarter to June 2026, against a year earlier

4.17 0.16 +3.99%
Market cap
$333.2M
P/E
0.0×
Fwd P/E
−3.8×
Dividend yield
—
F-score
5/9
Altman Z
−4.35
Beneish M
−4.00
Dividend safety
n/a

Insider Decisions last twelve months

Bought, $m 0.32
Sold, $m 19.68
Trades a month
Jan 26 Apr 26 Jul 26 Oct 26
Buy 1 — — — — — — — — — — —
Sell 1 — — 4 6 1 — 4 — 2 4 1
Insider Ownership 29.33%

Capital & Financial Ratios $m

Size
Market Cap 333.20
Revenue ttm 9.86
Net income ttm (107.61)
Free cash flow ttm (40.67)
Net debt Q (53.88)
Valuation
P/E 0.00
Forward P/E (3.75) (negative: loss-making)
Price / sales 40.40 (above 10: high)
Forward P/S Powerpack
Price / FCF 0.00
Price / book 0.00
Financial health
Current ratio Q 12.19 (at or above 1.5: strong)
Debt / equity Q (2.69) (negative: negative equity)
Interest coverage Q (208.17)
Growth
Revenue growth Q −73.80% (below 0%: shrinking)
Operating income growth Q −85.04% (below 0%: shrinking)
EPS, this year −28.82% (below 0%: weak)
EPS, next year A +31.68% (at or above 15%: strong)
Revenue, next year A −3.14% (below 0%: weak)
EPS, past 5 yrs —
EPS, next 5 yrs A +33.47% (at or above 15%: strong)

Green and red mark values outside typical ranges; (Q) is the latest quarter, (A) analysts’ estimates. How we judge →

Valuation vs history

P/S against its own 10 years 88.02%
10-year low 10-year high
EV/Sales against its own 10 years 93.55%
10-year low 10-year high

Dividends

Yield
—
Annual rate
—
Payout ratio
—

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 51 30 45 89
Receivables 1 4 2 1
Inventory — — — —
Other 1 2 1 0
54 37 50 93
2023 2024 2025 Q'26
Payables 2 3 3 2
ST’ Debt — — — —
Other 0 0 — —
4 11 8 8

Compound Annual Growth %

10y 5y 3y
Sales — — (29.11%)
Cash Flow 0.00% 0.00% 0.00%
Earnings 0.00% 0.00% 0.00%
Book Value (2.00%) 0.00% (30.76%)

Earnings Trends EPS, adjusted, against the consensus

EPS $

Mar Jun Sep Dec Year
’26 (0.75) (0.14) — — —
’25 (0.24) (0.12) (0.25) (0.21) (0.80)
’24 (0.29) (0.30) (0.29) (1.27) (2.15)
’23 (0.28) (0.24) 0.25 (0.21) (0.46)
’22 (0.35) (0.25) (0.22) 1.58 0.87
’21 (3.57) (0.52) (0.25) (0.35) (3.82)
’20 (0.87) (0.43) (0.33) (3.65) (5.28)
Fiscal quarters ending in the months shown.

Revenue $m

Mar Jun Sep Dec Year
’26 2 1 — — —
’25 4 3 3 4 14
’24 2 1 4 4 11
’23 2 4 12 2 19
’22 — — — 40 40
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (13) (12) — — —
’25 (9) (10) (6) (10) (35)
’24 (6) (7) (5) (7) (26)
’23 (4) 1 (3) 5 (1)
’22 (6) (4) (4) 29 14
’21 (6) (4) (4) (6) (19)
’20 (1) (1) (1) (4) (7)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (13) (12) — — —
’25 (9) (10) (6) (10) (35)
’24 (6) (7) (5) (7) (26)
’23 (4) 1 (3) 5 (1)
’22 (6) (4) (4) 29 14
’21 (6) (4) (4) (6) (19)
’20 (1) (1) (1) (6) (8)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Ten-year view Analyst estimates Powerpack
Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 TTM Jun ’26 Trend 10 yrs 2026e 2027e 2028e Next 3/yr
Income, $m
Income, $m Revenue — — — — — 1 40 19 11 14 10 +121.6% 14 14 45 +47.3%
Gross margin, % — — 0.00 0.00 0.00 100.00 100.00 100.00 100.00 100.00 100.00 +100.0 pt
EBT (9) (25) (14) (6) (25) (57) 18 (10) (58) (50) (108) +20.4%
EBT margin, % 0.00 0.00 0.00 0.00 0.00 (9,625.30) 45.68 (52.36) (523.40) (349.33) (1,091.82) (349.3) pt
Net income (9) (25) (14) (6) (25) (57) 18 (10) (58) (50) (108) +20.4%
Per share, $
Per share, $ Revenue 0.00 0.00 0.00 0.00 0.00 0.04 2.00 0.88 0.41 0.23 0.10 n/m
Earnings (19.21) (44.18) (21.13) (2.17) (5.28) (3.82) 0.90 (0.46) (2.15) (0.80) (1.29) (29.8%)
Cash flow (29.21) (27.03) (27.51) (1.26) (1.46) (1.30) 0.72 (0.05) (0.96) (0.57) (0.43) (35.5%)
Capex (0.02) (0.13) (0.06) (0.01) (0.32) (0.01) 0.00 0.00 0.00 0.00 0.00 n/m
Free cash flow (29.23) (27.17) (27.57) (1.27) (1.77) (1.31) 0.72 (0.05) (0.96) (0.57) (0.43) (35.5%)
Book value 37.67 29.40 15.42 (2.66) (2.89) 1.50 2.32 2.31 0.25 0.25 (0.14) (42.8%)
Shares, m 0 1 1 3 5 15 20 22 27 62 79 +72.8%
Valuation, ×
Valuation, × P/E — — — — — 0.00 4.33 0.00 0.00 0.00 0.00 0.9
P/S — — — — — 31.86 1.73 3.48 2.89 8.81 40.40 9.8
P/B — — — — — 2.49 1.51 1.33 4.73 8.15 0.00 3.6
EV/Sales — — — — — 17.95 0.68 0.84 0.16 5.72 34.95 5.1
EV/FCF — — — — — (1.49) 2.16 (5.93) (0.06) (2.21) (8.15) (1.5)
Cash, $m
Cash, $m Operating cash flow (13) (15) (19) (4) (7) (19) 14 (1) (26) (35) (41) +11.5%
Capex 0 0 0 0 (1) 0 — — — — (2) +63.0%
Free cash flow (13) (15) (19) (4) (8) (19) 14 (1) (26) (35) (41) +11.5%
Balance, $m
Balance, $m Working capital 19 25 13 (8) 14 22 46 50 25 42 85 +9.3%
Net debt (20) (27) (15) 4 (16) (24) (43) (51) (30) (45) (54) +9.3%
Shareholders’ equity 17 17 11 (8) (13) 22 46 50 7 15 (13) (1.2%)
Returns, %
Returns, % ROA (40.60) (102.55) (64.82) (69.21) (252.95) (259.11) 47.66 (19.40) (126.71) (113.86) (163.50) (73.3) pt
ROIC 0.00 0.00 0.00 0.00 0.00 0.00 320.34 0.00 0.00 0.00 0.00 0.0 pt
ROE (51.95) (149.55) (105.14) (410.87) 234.18 (1,295.10) 52.26 (20.77) (203.19) (449.36) (4,796.52) (397.4) pt
People
People Employees 20 17 10 5 5 8 9 14 18 28 — +3.8%
Revenue/emp, $m 0.00 0.00 0.00 0.00 0.00 0.07 4.43 1.36 0.61 0.51 — n/m
Negative figures in brackets.
estimates

All 10 years →

Fiscal years to Dec 2025 · latest quarter Jun 2026 · fundamentals updated 26 Oct 2026

Opus Genetics, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
MPLT MapLight Therapeutics, Inc. $345.7M — (loss-making) — — n/m −31.91% (below 0%: shrinking) — 0.00% Compare
AGMB AgomAb Therapeutics NV $343.3M — — — — — — — Compare
SRZN Surrozen, Inc. $340.9M — (loss-making) — (loss-making) +408.65% (above 0%: growing) n/m −21.25% (below 0%: shrinking) 100.00% (207.40%) Compare
AVIR Atea Pharmaceuticals, Inc. $338.5M — (loss-making) — (loss-making) +295.16% (above 0%: growing) n/m +85.53% (above 0%: growing) 0.00% 0.00% Compare
OBIO Orchestra BioMed Holdings, Inc. $337.8M — (loss-making) — (loss-making) −89.47% (below 0%: shrinking) n/m −25.87% (below 0%: shrinking) 71.59% (25,404.55%) Compare
AUTL Autolus Therapeutics PLC Sponsored ADR $335.4M — (loss-making) — (loss-making) +118.37% (above 0%: growing) n/m +67.55% (above 0%: growing) 55.20% (95.95%) Compare
IRD Opus Genetics, Inc. $333.2M — (loss-making) — (loss-making) −73.80% (below 0%: shrinking) n/m −16.37% (below 0%: shrinking) 100.00% (2,182.78%)
FENC Adherex Technologies Inc. $329.3M — (loss-making) 34.1× +85.18% (above 0%: growing) n/m +101.36% (above 0%: growing) 95.97% 9.72% Compare
PROK ProKidney Corp. $322.0M — (loss-making) — (loss-making) −32.13% (below 0%: shrinking) n/m −28.03% (below 0%: shrinking) 100.00% (32,248.67%) Compare
Median of peers $338.1M — — +101.78% — −21.25% 83.78% (95.95%)

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Pay and ownership Proxy statement filed 23 March 2026

Ownership

Directors and executive officers, together 11.70%
Perceptive Advisors LLC 9.99%
Nantahala Capital Management, LLC 9.99%
Foundation Fighting Blindness Retinal Degeneration Fund 7.70%
Balyasny Asset Management L.P. 7.20%
Bios Fund III, LP 5.20%
Ownership is the proxy’s own table: the directors and officers as a group, and every holder of 5% or more. Read the proxy statement

Opus Genetics, Inc. (IRD) Latest News

13 Oct

1 Sep

stockrow.com/IRD · Data as of Oct 26, 2026 · For information only; not investment advice. · © 2026 stockrow.com