Spyre Therapeutics, Inc.

SYRE Healthcare Biotechnology

Spyre Therapeutics, Inc.’s revenue for fiscal 2023 (year ended December 2023) was $886,000.00, down 62.0% from fiscal 2022.

EPS
−624.8%
Free cash flow
−108.8%

Quarter to September 2026, against a year earlier

103.23 6.64 +6.87%
Market cap
$9.2B
P/E
0.0×
Fwd P/E
−4.8×
Dividend yield
—
F-score
3/9
Altman Z
−3.82
Beneish M
n/a
Dividend safety
n/a

Spyre Therapeutics, Inc. (SYRE) Book value per share

Alert me on Book value per share

Spyre Therapeutics, Inc.'s book value per share at the end of fiscal 2025 was 11.2×, unchanged from fiscal 2024. At the end of the quarter to 30 September 2026 it was 11.9×. Over the past ten years it has ranged from 11.0× (fiscal 2024) to 1,504× (fiscal 2015); the current reading is higher than 18% of that period. Spyre Therapeutics, Inc. ranks 68th of 611 Biotechnology companies by book value per share.

Book value per share, annual

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Annual newest first

Period Book value per share Change
FY2025 11.2× 1.41%
FY2024 11.0× (58.73%)
FY2023 26.7× 78.79%
FY2022 14.9× (53.25%)
FY2021 31.9× (51.27%)
FY2020 65.5× 39.32%
FY2019 47.0× (41.93%)
FY2018 81.0× (2.68%)
FY2017 83.2× (48.25%)
FY2016 161× (89.31%)

Quarterly newest first

Period Book value per share Change
Sep 2026 11.9× (8.48%)
Jun 2026 13.0× 52.18%
Mar 2026 8.5× (23.52%)
Dec 2025 11.2× 48.22%
43 more quarters

Against its own ten years

Low 11.0× High 1,504×
Ten-year median 47.0×
Current reading's percentile 18

Book value per share against peers

What Book value per share is

BV per Share tells an investor how much of a company’s accounting net worth stands behind each share.

(Shareholders Equity (Total) ÷ Shares (Basic, Weighted))

The full definition of Book value per share →

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