Spero Therapeutics, Inc.
SPROSpero Therapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $66.8 million, up 39.2% from fiscal 2024.
- Revenue
- −95.6%
- EPS
- −433.3%
- Free cash flow
- +69.7%
Quarter to June 2026, against a year earlier
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Spero Therapeutics, Inc. (SPRO) Return on invested capital
Spero Therapeutics, Inc.'s return on invested capital over the twelve months to 30 June 2026 was 0.00%, down 21.0 percentage points from fiscal 2025 (21.0%). Over the past ten years it has ranged from −6,493.6% (fiscal 2018) to 43.9% (fiscal 2023); the current reading is higher than 91% of that period. That is in line with the Biotechnology industry median of 0.00% and in line with the Healthcare sector median of 0.00%.
Return on invested capital, annual
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Annual newest first
| Period | Return on invested capital | Change (points) |
|---|---|---|
| FY2025 | 21.0% | 21.04 |
| FY2024 | 0.00% | (43.93) |
| FY2023 | 43.9% | 43.93 |
| FY2022 | 0.00% | 0.00 |
| FY2021 | 0.00% | 963.10 |
| FY2020 | −963.1% | (963.10) |
| FY2019 | 0.00% | 6,493.63 |
| FY2018 | −6,493.6% | (6,493.63) |
| FY2017 | 0.00% | 0.00 |
| FY2016 | 0.00% | 0.00 |
Against its own ten years
Return on invested capital against peers
| Company | Return on invested capital |
|---|---|
| CRBP Corbus Pharmaceuticals Holdings, Inc. compare | 0.00% |
| CLNN Clene Inc. compare | 0.00% |
| CING Cingulate Inc. compare | 0.00% |
| CRDF Cardiff Oncology, Inc. compare | 0.00% |
| GOSS Gossamer Bio, Inc. compare | 0.00% |
| SPRO Spero Therapeutics, Inc. | 0.00% |
| NORD Nordicus Partners Corporation compare | −4.43% |
| FBIO Fortress Biotech, Inc. compare | −41.3% |
| XBIT XBiotech Inc. compare | −159.2% |
| Biotechnology industry median | 0.00% |
| Healthcare sector median | 0.00% |
| Market median | 0.00% |
What Return on invested capital is
Return on Invested Capital shows how much after-tax operating profit a company earns on the money its lenders and shareholders have put in.
TTM: (Operating Income × 0.625) ÷ (Shareholders Equity (Total) (latest quarter) + Long Term Debt (Total) (latest quarter) + Current Part of Debt (latest quarter) − Cash & Short Term Investments (latest quarter)); Annual: (Operating Income × 0.625) ÷ (Shareholders Equity (Total) + Long Term Debt (Total) + Current Part of Debt − Cash & Short Term Investments)