Clene Inc.

CLNN Healthcare Biotechnology

Clene Inc.’s revenue for fiscal 2025 (year ended December 2025) was $200,000.00, down 41.5% from fiscal 2024.

Revenue
+273.3%
EPS
+135.2%
Free cash flow
−16.6%
Total debt
−60.3%

Quarter to September 2026, against a year earlier

3.85 0.12 −3.02%
Market cap
$56.4M
P/E
0.0×
Fwd P/E
−1.5×
Dividend yield
—
F-score
2/9
Altman Z
−27.14
Beneish M
n/a
Dividend safety
n/a

Insider Decisions last twelve months

Bought, $m 0.22
Sold, $m 5.78
Trades a month
Jan 26 Apr 26 Jul 26 Oct 26
Buy — 1 — — — — — — — — — —
Sell 5 7 1 2 5 2 — — — — — —
Insider Ownership 13.46%

Capital & Financial Ratios $m

Size
Market Cap 56.43
Revenue ttm 0.24
Net income ttm (26.83)
Free cash flow ttm (16.62)
Net debt Q (3.63)
Valuation
P/E 0.00
Forward P/E (1.49) (negative: loss-making)
Price / sales 211.59 (above 10: high)
Forward P/S Powerpack
Price / FCF 0.00
Price / book 0.00
Financial health
Current ratio Q 0.85 (below 1: weak)
Debt / equity Q (0.42) (negative: negative equity)
Interest coverage Q (9.54)
Growth
Revenue growth Q +273.33% (above 0%: growing)
Operating income growth Q −12.38% (below 0%: shrinking)
EPS, this year +12.68%
EPS, next year A +35.52% (at or above 15%: strong)
Revenue, next year A −81.42% (below 0%: weak)
EPS, past 5 yrs —
EPS, next 5 yrs A +65.56% (at or above 15%: strong)

Green and red mark values outside typical ranges; (Q) is the latest quarter, (A) analysts’ estimates. How we judge →

Valuation vs history

P/S against its own 10 years 51.16%
10-year low 10-year high
EV/Sales against its own 10 years 49.52%
10-year low 10-year high

Dividends

Yield
—
Annual rate
—
Payout ratio
—

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 35 12 5 10
Receivables 0 0 — 0
Inventory 0 0 0 0
Other — — — —
39 16 9 14
2023 2024 2025 Q'26
Payables 2 1 1 1
ST’ Debt — — — —
Other — — — —
25 10 11 17

Compound Annual Growth %

10y 5y 3y
Sales — (0.59%) (24.94%)
Cash Flow 0.00% 0.00% 0.00%
Earnings 0.00% 0.00% 0.00%
Book Value 0.00% 0.00% 0.00%

Earnings Trends EPS, adjusted, against the consensus

EPS $

Mar Jun Sep Dec Year
’26 (0.69) (1.08) 0.27 — —
’25 (0.09) (0.78) (0.85) (0.88) (2.65)
’24 (1.80) (1.06) (1.22) (1.67) (5.67)
’23 (3.00) (5.80) (0.40) (1.57) (9.40)
’22 (4.20) (1.40) (3.40) 0.00 (9.20)
’21 (13.20) (1.00) 8.40 1.40 (3.20)
’20 (4.54) (6.70) (11.86) 1.08 (22.00)
Fiscal quarters ending in the months shown.

Revenue $m

Mar Jun Sep Dec Year
’26 0 0 0 — —
’25 0 0 0 0 0
’24 0 0 0 0 0
’23 0 0 0 0 1
’22 0 0 0 0 0
’21 0 0 0 0 1
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (5) (3) (5) — —
’25 (5) (5) (4) (5) (19)
’24 (7) (6) (3) (5) (21)
’23 (9) (7) (7) (7) (30)
’22 (13) (10) (8) (8) (39)
’21 (9) (9) (7) (10) (35)
’20 (3) (2) (8) (6) (19)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (5) (3) (5) — —
’25 (5) (5) (4) (5) (19)
’24 (7) (6) (3) (5) (21)
’23 (9) (7) (7) (7) (31)
’22 (14) (11) (10) (9) (44)
’22 — — — — (39)
’21 (9) (9) (8) (10) (36)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Ten-year view Analyst estimates Powerpack
Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 TTM Sep ’26 Trend 10 yrs 2026e 2027e 2028e Next 3/yr
Income, $m
Income, $m Revenue — — — — 0 1 0 1 0 0 0 (0.6%) 0 3 24 +394.6%
Gross margin, % — — — 0.00 68.45 60.03 94.50 81.50 79.53 78.50 68.49 +78.5 pt
EBT — 0 0 (16) (19) (10) (30) (50) (39) (26) (27) n/m
EBT margin, % — 0.00 0.00 0.00 (9,160.68) (1,406.36) (6,325.16) (7,569.42) (11,520.47) (13,086.50) (11,271.43) (13,086.5) pt
Net income — 0 0 (16) (19) (10) (30) (50) (39) (26) (27) n/m
Per share, $
Per share, $ Revenue — 0.00 0.00 0.00 0.24 0.23 0.15 0.12 0.05 0.02 0.02 n/m
Earnings — 0.00 (4.00) (18.61) (22.00) (3.20) (9.20) (9.40) (5.67) (2.65) (2.35) n/m
Cash flow — 0.00 (3.02) (15.21) (21.63) (11.25) (11.97) (5.75) (3.07) (1.88) (1.26) n/m
Capex — 0.00 0.00 (0.34) (0.44) (0.43) (1.59) (0.06) 0.00 0.00 (0.01) n/m
Free cash flow — 0.00 (3.02) (15.54) (22.07) (11.68) (13.55) (5.81) (3.07) (1.89) (1.27) n/m
Book value — 0.00 73.64 (78.09) 0.39 4.09 0.99 2.55 (1.27) (1.78) (1.13) n/m
Shares, m — 2 0 1 1 3 3 5 7 10 12 +22.7%
Valuation, ×
Valuation, × P/E — — — — 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.0
P/S — — — — 765.59 349.08 130.96 47.17 107.97 289.36 211.59 281.7
P/B — — — — 462.50 20.04 19.14 2.30 0.00 0.00 0.00 84.0
EV/Sales — — — — 488.30 306.06 122.45 12.09 117.53 331.12 196.34 229.6
EV/FCF — — — — (5.21) (6.15) (1.31) (0.26) (1.88) (3.56) (2.81) (3.1)
Cash, $m
Cash, $m Operating cash flow — 0 0 (13) (19) (35) (39) (30) (21) (19) (17) n/m
Capex — 0 — 0 0 (1) (5) 0 0 0 0 n/m
Free cash flow — 0 0 (13) (19) (36) (44) (31) (21) (19) (17) n/m
Balance, $m
Balance, $m Working capital — 0 1 5 51 49 15 14 6 (2) (3) +128.7%
Net debt — — (1) (8) (57) (31) (4) (23) 3 8 (4) n/m
Shareholders’ equity — 0 5 (68) 0 13 3 13 (9) (18) (15) +204.2%
Returns, %
Returns, % ROA — 0.00 (1.17) (52.08) (46.38) (14.84) (55.63) (102.25) (98.90) (115.13) (120.65) (115.1) pt
ROIC — 0.00 (4.76) 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.0 pt
ROE — 0.00 (11.10) 51.47 57.17 (150.56) (377.90) (595.47) (1,738.36) 197.91 197.50 +197.9 pt
People
People Employees — — — — 74 102 86 85 76 79 — +1.3%
Revenue/emp, $m — — — — 0.00 0.01 0.01 0.01 0.00 0.00 — (1.9%)
Negative figures in brackets.
estimates

All 10 years →

Fiscal years to Dec 2025 · latest quarter Sep 2026 · fundamentals updated 6 Nov 2026

Clene Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
CRDF Cardiff Oncology, Inc. $58.8M — (loss-making) — (loss-making) −14.05% (below 0%: shrinking) n/m −41.36% (below 0%: shrinking) 100.00% (9,245.19%) Compare
GOSS Gossamer Bio, Inc. $57.6M — (loss-making) — (loss-making) −19.59% (below 0%: shrinking) n/m +16.32% (above 0%: growing) 100.00% (282.25%) Compare
TELO Telomir Pharmaceuticals, Inc. $57.5M — (loss-making) — — n/m −45.34% (below 0%: shrinking) — 0.00% Compare
XBIT XBiotech Inc. $57.0M — (loss-making) — (loss-making) −93.33% (below 0%: shrinking) n/m +25.25% (above 0%: growing) 0.00% 0.00% Compare
CLNN Clene Inc. $56.4M — (loss-making) — (loss-making) +273.33% (above 0%: growing) n/m −16.61% (below 0%: shrinking) 71.43% (11,333.93%)
XLO Xilio Therapeutics, Inc. $55.9M — (loss-making) — (loss-making) +131.22% (above 0%: growing) n/m −26.23% (below 0%: shrinking) 100.00% (18.68%) Compare
CRBP Corbus Pharmaceuticals Holdings, Inc. $55.3M — (loss-making) — (loss-making) −92.09% (below 0%: shrinking) n/m −78.52% (below 0%: shrinking) 0.00% 0.00% Compare
BOLD Boundless Bio, Inc. $54.8M — (loss-making) — — n/m −76.90% (below 0%: shrinking) — 0.00% Compare
RNXT RenovoRx, Inc. $53.7M — (loss-making) — (loss-making) +300.75% (above 0%: growing) n/m −12.69% (below 0%: shrinking) 82.36% (303.56%) Compare
Median of peers $56.5M — — −16.82% — −33.79% 91.18% (9.34%)

All 621 Biotechnology stocks →

Clene Inc. (CLNN) Latest News

12 Aug

Impact 4 · · MarketBeat

16 Jan

Impact 3 · · GlobeNewswire

9 Jan

9 Dec

Impact 3 · · GlobeNewswire

2 Dec

Impact 4 · · GlobeNewswire

20 Oct

Impact 3 · · GlobeNewswire

16 Aug

Impact 3 · · Simply Wall St.

13 Aug

Impact 3 · · GlobeNewswire
stockrow.com/CLNN · Data as of Nov 6, 2026 · For information only; not investment advice. · © 2026 stockrow.com