Cardiff Oncology, Inc. (CRDF) vs Spero Therapeutics, Inc. (SPRO)

Cardiff Oncology, Inc. and Spero Therapeutics, Inc. are both Biotechnology companies. Cardiff Oncology, Inc. and Spero Therapeutics, Inc. are of similar size ($59.4M and $58.8M). Cardiff Oncology, Inc. has negative trailing earnings, so its P/E is not meaningful; Spero Therapeutics, Inc. trades at 7.4×. Spero Therapeutics, Inc. grew revenue faster over the last twelve months: 37.2% against −6.79%. Spero Therapeutics, Inc. has the higher net margin (0.00% vs −7,889.0%) and the higher return on invested capital (0.00% vs 0.00%). Across the 15 metrics below, Spero Therapeutics, Inc. leads on 15 and Cardiff Oncology, Inc. on 0.

Valuation

Metric CRDF SPRO Biotechnology median
P/E n/m 7.43 10.60
P/S 105.02 0.99 9.40
P/B 2.01 1.36 2.13
Price to free cash flow n/m 3.09 25.18
EV/EBITDA n/m 1.58 0.66
EV/Sales 39.84 0.16 9.02
Earnings yield (76.92%) 13.46% (32.88%)
Free cash flow yield (76.74%) 32.41% (23.13%)

Profitability

Metric CRDF SPRO Biotechnology median
Gross margin 100.00% 100.00% 68.51%
Operating margin (8,320.08%) 0.00% 0.00%
Net margin (7,888.98%) 0.00% 0.00%
Free cash flow margin (8,059.45%) 0.00% 0.00%
Return on equity (94.14%) 19.17% (51.96%)
Return on assets (70.89%) 12.85% (46.06%)
Return on invested capital 0.00% 0.00% 0.00%

Growth

Metric CRDF SPRO Biotechnology median
Revenue growth (TTM) (6.79%) 37.24% 6.76%
EPS growth (last fiscal year) 27.37% 111.81% 29.88%
Revenue growth, 5-year CAGR 10.13% 48.25% 9.75%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric CRDF SPRO Biotechnology median
Debt to equity 0.00 0.00 0.00
Current ratio 3.30 6.12 4.97
Net debt to EBITDA 1.18 (6.38) 1.01

Dividend

Metric CRDF SPRO Biotechnology median
Dividend yield — — 0.41%
Payout ratio — — —

Size

Metric CRDF SPRO Biotechnology median
Market cap 58.76m 59.40m 161.82m

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