Ultragenyx Pharmaceutical Inc.

RARE Healthcare Biotechnology

Ultragenyx Pharmaceutical Inc.’s revenue for fiscal 2025 (year ended December 2025) was $673.0 million, up 20.2% from fiscal 2024. In the quarter to June 2026, revenue grew 28.1%, EPS grew 23.1% and free cash flow grew 12.5%, each against the same quarter a year earlier. Revenue growth for five consecutive years.

14.54 0.63 −4.15%
Market cap
$1.5B
P/E
0.0×
Fwd P/E
−4.8×
Dividend yield
—
F-score
5/9
Altman Z
−3.57
Beneish M
−2.68
Dividend safety
n/a

Insider Decisions trades per month

Total sells 3.70
Totals in millions of $.
Dec 25 Mar 26 Jun 26 Sep 26
Buy — — — — — — — — — — — —
Sell — 2 1 1 8 1 3 3 1 2 2 —
Insider Ownership 11.49%

Capital & Financial Ratios $m

Market Cap 1,500.00
Revenue 717.00
Net Income (586.00)
Free Cash Flow (494.00)
Net Debt (292.00)
Current Ratio 1.73 (at or above 1.5: strong)
Debt/Equity 0.00 (at or below 0.5: strong)
P/E ratio 0.00
Fwd P/E (4.84) (negative: loss-making)
P/S ratio 2.07
P/B ratio 0.00
Past 5Y EPS Growth —
This Y EPS Growth 21.03% (at or above 15%: strong)
Next Y EPS Growth 85.10% (at or above 15%: strong)
Next Y revenue growth 13.16% (at or above 10%: strong)
Next 5Y EPS Growth 71.02% (at or above 15%: strong)

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/S against its own 10 years 0.57%
10-year low 10-year high
EV/Sales against its own 10 years 0.57%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2025 Powerpack
2024 Powerpack
2023 Powerpack
2022 Powerpack
2021 Powerpack
2020 Powerpack
2019 Powerpack
2017 Powerpack
predictions special payouts not included in total or ratios

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 577 610 680 292
Receivables 73 122 158 200
Inventory 34 45 52 59
Other — — — —
732 817 951 606
2023 2024 2025 Q'26
Payables 42 39 31 39
ST’ Debt — — — —
Other 29 54 76 91
280 344 384 351

Compound Annual Growth %

10y 5y 3y
Sales — 19.95% 22.81%
Cash Flow 0.00% 0.00% 0.00%
Earnings 0.00% 0.00% 0.00%
Book Value 0.00% 0.00% 0.00%

Revenue $m

Mar Jun Sep Dec Year
’26 136 214 — — —
’25 139 167 160 207 673
’24 109 147 139 165 560
’23 100 108 98 127 434
’22 80 89 91 103 363
’21 99 87 82 83 351
’20 36 62 81 92 271
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (197) (97) — — —
’25 (166) (109) (91) (100) (466)
’24 (191) (77) (67) (79) (414)
’23 (157) (116) (118) (84) (475)
’22 (118) (77) (95) (90) (380)
’21 (159) (65) (60) (54) (339)
’20 (95) 87 (62) (62) (132)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (203) (98) — — —
’25 (182) (112) (92) (101) (487)
’24 (204) (81) (69) (80) (434)
’23 (182) (133) (122) (86) (522)
’22 (180) (108) (121) (117) (527)
’21 (176) (85) (80) (70) (412)
’20 (109) 83 (66) (84) (176)
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 (1.84) (0.90) — — —
’25 (1.57) (1.17) (1.81) (1.29) (5.83)
’24 (2.03) (1.52) (1.40) (1.39) (6.29)
’23 (2.33) (2.25) (2.23) (1.52) (8.25)
’22 (2.19) (2.26) (3.50) (2.16) (10.12)
’21 (2.03) (1.81) (1.08) (1.79) (6.70)
’20 (2.05) 0.41 (1.13) (0.37) (3.07)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

2.1
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low 46.52 43.14 37.44 35.41 31.99 72.89 33.36 31.52 37.02 18.41

Analyst estimates 2026–2028

Powerpack
High 110.06 91.35 90.98 74.50 179.65 175.00 88.12 54.98 60.37 46.50
People
People Employees 376 520 610 740 893 1,119 1,311 1,276 1,294 1,371
Revenue/emp, $m 0.00 0.01 0.08 0.14 0.30 0.31 0.28 0.34 0.43 0.49
Income, $m
Income, $m Revenue 0 3 51 104 271 351 363 434 560 673
Gross margin, % 100.00 99.96 97.77 91.31 97.74 95.44 92.21 89.63 86.25 83.80
EBT (246) (318) (197) (399) (185) (453) (702) (609) (567) (571)
EBT margin, % (184,841.35) (12,187.52) (382.75) (385.14) (68.39) (128.91) (193.14) (140.32) (101.25) (84.84)
Net income (246) (302) (198) (403) (187) (454) (707) (607) (569) (575)
Depreciation 8 8 17 2 13 20 21 13 23 31
Per share, $
Per share, $ Revenue 0.00 0.06 1.03 1.83 4.45 5.18 5.20 5.90 6.19 6.83
Earnings (6.21) (7.12) (3.97) (7.12) (3.07) (6.70) (10.12) (8.25) (6.29) (5.83)
Cash flow (4.07) (5.98) (5.84) (6.10) (2.17) (5.00) (5.44) (6.46) (4.57) (4.73)
Capex (0.26) (0.07) (0.08) (0.44) (0.72) (1.08) (2.09) (0.64) (0.22) (0.21)
Free cash flow (4.32) (6.05) (5.92) (6.54) (2.89) (6.07) (7.53) (7.10) (4.80) (4.94)
Book value 11.97 9.03 12.23 11.56 18.97 13.61 5.04 3.75 2.82 (0.81)
Shares, m 40 42 50 57 61 68 70 74 91 99
Valuation, ×
Valuation, × P/E 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
P/S 0.00 767.05 42.03 23.30 31.08 16.22 8.76 8.16 6.80 3.37
P/B 5.84 5.46 3.55 3.70 7.30 6.18 9.03 12.86 14.93 0.00
EV/Sales 0.00 681.09 33.10 16.02 26.64 14.12 6.70 6.83 5.71 2.36
EV/FCF (13.95) (7.24) (5.78) (4.49) (41.00) (12.05) (4.62) (5.68) (7.37) (3.26)
Cash, $m
Cash, $m Operating cash flow (161) (254) (291) (345) (132) (339) (380) (475) (414) (466)
Capex (10) (3) (4) (25) (44) (73) (146) (47) (20) (21)
Free cash flow (171) (257) (295) (370) (176) (412) (527) (522) (434) (487)
Balance, $m
Balance, $m Working capital 341 199 448 748 1,106 675 623 452 473 567
Total debt — — — 352 384 394 907 — — —
Net debt (382) (234) (460) (755) (1,202) (740) (748) (577) (610) (680)
Shareholders’ equity 474 383 609 654 1,154 923 352 275 255 (80)
Returns, %
Returns, % ROA (44.70) (58.59) (32.65) (43.42) (12.89) (27.67) (46.12) (39.98) (38.01) (37.89)
ROIC (167.73) (138.02) (155.57) 0.00 0.00 (130.83) 0.00 0.00 0.00 0.00
ROE (48.93) (70.48) (39.83) (63.79) (20.64) (43.72) (110.96) (193.34) (214.55) (657.14)
Negative figures in brackets.

All 10 years →

Fiscal years to Dec 2025 · latest quarter Jun 2026

Charts ten years each

Ultragenyx Pharmaceutical Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
GPCR Structure Therapeutics Inc. Sponsored ADR $1.6B — (loss-making) — — n/m −119.15% (below 0%: shrinking) 0.00% 0.00% Compare
QURE uniQure N.V. $1.6B — (loss-making) — (loss-making) +11.00% (above 0%: growing) n/m +27.66% (above 0%: growing) 94.01% (893.73%) Compare
KRSA Korsana Biosciences, Inc. $1.5B — (loss-making) — (loss-making) −43.24% (below 0%: shrinking) n/m −184.69% (below 0%: shrinking) 100.00% 0.00% Compare
MAZE Maze Therapeutics, Inc. $1.5B — (loss-making) — — n/m +50.21% (above 0%: growing) 100.00% 0.00% Compare
ABSI Absci Corporation $1.5B — (loss-making) — (loss-making) −46.37% (below 0%: shrinking) n/m −71.74% (below 0%: shrinking) 100.00% (10,741.51%) Compare
IMCR Immunocore Holdings PLC Sponsored ADR $1.5B — (loss-making) 208× +18.34% (above 0%: growing) n/m −40.74% (below 0%: shrinking) 99.06% (2.58%) Compare
RARE Ultragenyx Pharmaceutical Inc. $1.5B — (loss-making) — (loss-making) +28.14% (above 0%: growing) n/m +12.50% (above 0%: growing) 84.11% (35.05%)
ANAB AnaptysBio, Inc. $1.5B — (loss-making) 220× −7.98% (below 0%: shrinking) n/m −141.60% (below 0%: shrinking) 100.00% (135.53%) Compare
RAPP Rapport Therapeutics, Inc. $1.4B — (loss-making) — — n/m −64.75% (below 0%: shrinking) 100.00% 0.00% Compare
Median of peers $1.5B — — −7.98% — −68.24% 100.00% (1.29%)

All 614 Biotechnology stocks →

Ultragenyx Pharmaceutical Inc. (RARE) key facts

  • Concern: Ultragenyx Pharmaceutical Inc. reported a net loss of $575.0 million, or a loss of $5.83 per share, for fiscal 2025.
  • Strength: Ultragenyx Pharmaceutical Inc.’s revenue for fiscal 2025 (year ended December 2025) was $673.0 million, up 20.2% from fiscal 2024.
  • Ultragenyx Pharmaceutical Inc. (RARE) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • As of October 16, 2026, RARE traded at $14.54, a market capitalization of $1.5 billion.
  • Trailing earnings are negative, so a P/E ratio is not meaningful; the stock trades at 2.1× sales.
  • Return on equity was −657.1% and debt-to-equity 0.00.
  • Its Piotroski F-score is 5 out of 9 and its Altman Z-score is −3.57 (distress zone) for fiscal 2025.

Source: company filings (standardised) and stockrow calculations.

Ultragenyx Pharmaceutical Inc. (RARE) Latest News

stockrow.com/RARE · Data as of Jun 30, 2026 · For information only; not investment advice. · © 2026 stockrow.com