Saturday 17 October 2026
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AnaptysBio, Inc.
ANAB Healthcare Biotechnology
AnaptysBio, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $234.6 million, up 157.0% from fiscal 2024. In the quarter to March 2026, revenue fell 7.98%, EPS fell 43.8% and free cash flow fell 141.6%, each against the same quarter a year earlier. Revenue growth for three consecutive years.
46.61
2.10
−4.31%
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Target Price Range
Analyst price targets
Free accountTen years at a glance Fiscal years to December
| Group | Line | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Trend | 2026e | 2027e | 2028e |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Price, $ | |||||||||||||||
| Price, $ | Low | — | 10.11 | 36.17 | 6.67 | 8.04 | 11.81 | 12.13 | 8.91 | 8.34 | 8.14 |
Analyst estimates 2026–2028 Powerpack |
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| High | — | 68.42 | 89.33 | 55.40 | 20.86 | 25.26 | 24.04 | 20.76 | 27.54 | 34.98 | |||||
| People | |||||||||||||||
| People | Employees | 49 | 60 | 78 | 89 | 94 | 102 | 96 | 117 | 136 | 104 | ||||
| Revenue/emp, $m | 0.34 | 0.17 | 0.06 | 0.09 | 0.80 | 0.62 | 0.11 | 0.15 | 0.67 | 2.26 | |||||
| Income, $m | |||||||||||||||
| Income, $m | Revenue | 17 | 10 | 5 | 8 | 75 | 63 | 10 | 17 | 91 | 235 | ||||
| Gross margin, % | 100.00 | 100.00 | 100.00 | 100.00 | 100.00 | 100.00 | 100.00 | 100.00 | 100.00 | 100.00 | |||||
| EBT | (4) | (30) | (62) | (97) | (20) | (58) | (129) | (164) | (145) | (13) | |||||
| EBT margin, % | (25.53) | (300.70) | (1,236.96) | (1,218.60) | (26.57) | (91.49) | (1,251.09) | (953.68) | (159.10) | (5.57) | |||||
| Net income | (4) | (30) | (62) | (97) | (20) | (58) | (129) | (164) | (145) | (13) | |||||
| Depreciation | 0 | 0 | (1) | (1) | 2 | 3 | 0 | (8) | (8) | (2) | |||||
| Per share, $ | |||||||||||||||
| Per share, $ | Revenue | 6.33 | 0.51 | 0.20 | 0.30 | 2.75 | 2.30 | 0.37 | 0.64 | 3.22 | 8.16 | ||||
| Earnings | (1.62) | (1.52) | (2.50) | (3.60) | (0.73) | (2.11) | (4.57) | (6.08) | (5.12) | (0.46) | |||||
| Cash flow | (3.42) | (0.98) | (1.97) | (2.57) | (0.52) | (1.67) | (2.61) | (4.49) | (4.77) | 0.68 | |||||
| Capex | (0.02) | (0.01) | (0.04) | (0.03) | (0.02) | (0.05) | (0.01) | (0.03) | (0.01) | 0.00 | |||||
| Free cash flow | (3.44) | (1.00) | (2.01) | (2.60) | (0.54) | (1.72) | (2.63) | (4.52) | (4.78) | 0.68 | |||||
| Book value | 14.89 | 15.55 | 19.71 | 14.97 | 14.53 | 12.99 | 9.31 | 3.27 | 2.50 | 1.29 | |||||
| Shares, m | 3 | 20 | 25 | 27 | 27 | 27 | 28 | 27 | 28 | 29 | |||||
| Valuation, × | |||||||||||||||
| Valuation, × | P/E | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | ||||
| P/S | 1.79 | 83.01 | 59.07 | 18.32 | 4.71 | 10.06 | 53.33 | 22.71 | 2.75 | 3.96 | |||||
| P/B | 0.00 | 4.31 | 2.16 | 0.72 | 0.99 | 1.78 | 2.09 | 4.42 | 3.54 | 24.98 | |||||
| EV/Sales | (0.45) | 67.94 | 35.16 | (4.92) | 0.00 | 1.42 | 10.68 | 0.06 | (1.45) | 2.64 | |||||
| EV/FCF | 0.83 | (55.02) | (12.60) | 1.12 | 0.00 | (1.90) | (1.49) | (0.01) | 0.98 | 31.63 | |||||
| Cash, $m | |||||||||||||||
| Cash, $m | Operating cash flow | (9) | (19) | (49) | (70) | (14) | (46) | (74) | (121) | (135) | 20 | ||||
| Capex | 0 | 0 | (1) | (1) | (1) | (1) | 0 | (1) | 0 | 0 | |||||
| Free cash flow | (9) | (20) | (50) | (70) | (15) | (47) | (74) | (122) | (136) | 20 | |||||
| Balance, $m | |||||||||||||||
| Balance, $m | Working capital | 53 | 239 | 412 | 348 | 377 | 538 | 421 | 369 | 386 | 312 | ||||
| Total debt | 14 | 8 | 1 | 1 | 0 | 19 | 322 | — | — | — | |||||
| Net debt | (37) | (241) | (427) | (374) | (394) | (548) | (441) | (391) | (385) | (312) | |||||
| Shareholders’ equity | 39 | 308 | 486 | 405 | 397 | 356 | 262 | 88 | 71 | 37 | |||||
| Returns, % | |||||||||||||||
| Returns, % | ROA | (7.19) | (15.36) | (14.71) | (20.62) | (4.68) | (10.91) | (20.54) | (30.79) | (31.02) | (3.12) | ||||
| ROIC | (102.47) | (26.96) | (70.34) | (218.14) | (484.87) | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |||||
| ROE | 11.60 | (22.33) | (15.53) | (21.84) | (4.97) | (15.35) | (41.62) | (93.44) | (182.71) | (24.49) | |||||
Negative figures in brackets.
Fiscal years to Dec 2025 · latest quarter Mar 2026
Charts ten years each
AnaptysBio, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier
| Company | Market cap | P/E | Fwd P/E | Revenue growth (Q) | EPS growth (Q) | FCF growth (Q) | Gross margin (Q) | EBIT margin (Q) | Compare |
|---|---|---|---|---|---|---|---|---|---|
| QURE uniQure N.V. | $1.6B | — (loss-making) | — (loss-making) | +11.00% (above 0%: growing) | n/m | +27.66% (above 0%: growing) | 94.01% | (893.73%) | Compare |
| KRSA Korsana Biosciences, Inc. | $1.5B | — (loss-making) | — (loss-making) | −43.24% (below 0%: shrinking) | n/m | −184.69% (below 0%: shrinking) | 100.00% | 0.00% | Compare |
| MAZE Maze Therapeutics, Inc. | $1.5B | — (loss-making) | — | — | n/m | +50.21% (above 0%: growing) | 100.00% | 0.00% | Compare |
| ABSI Absci Corporation | $1.5B | — (loss-making) | — (loss-making) | −46.37% (below 0%: shrinking) | n/m | −71.74% (below 0%: shrinking) | 100.00% | (10,741.51%) | Compare |
| IMCR Immunocore Holdings PLC Sponsored ADR | $1.5B | — (loss-making) | 208× | +18.34% (above 0%: growing) | n/m | −40.74% (below 0%: shrinking) | 99.06% | (2.58%) | Compare |
| RARE Ultragenyx Pharmaceutical Inc. | $1.5B | — (loss-making) | — (loss-making) | +28.14% (above 0%: growing) | n/m | +12.50% (above 0%: growing) | 84.11% | (35.05%) | Compare |
| ANAB AnaptysBio, Inc. | $1.5B | — (loss-making) | 220× | −7.98% (below 0%: shrinking) | n/m | −141.60% (below 0%: shrinking) | 100.00% | (135.53%) | |
| RAPP Rapport Therapeutics, Inc. | $1.4B | — (loss-making) | — | — | n/m | −64.75% (below 0%: shrinking) | 100.00% | 0.00% | Compare |
| AAPG Ascentage Pharma Group International - Unsponsored ADR | $1.4B | — | — | — | — | +17.74% (above 0%: growing) | — | — | Compare |
| Median of peers | $1.5B | — | — | +11.00% | — | −14.12% | 100.00% | (2.58%) |
AnaptysBio, Inc. (ANAB) key facts
- Strength: AnaptysBio, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $234.6 million, up 157.0% from fiscal 2024.
- AnaptysBio, Inc. (ANAB) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
- As of October 16, 2026, ANAB traded at $46.61, a market capitalization of $1.5 billion.
- Return on equity was −24.5% and debt-to-equity 0.00.
- Its Piotroski F-score is 5 out of 9 and its Altman Z-score is 0.84 (distress zone) for fiscal 2025.