Saturday 17 October 2026
Export RARE’s income statement to Excel — free account
Ultragenyx Pharmaceutical Inc.
RARE Healthcare Biotechnology
Ultragenyx Pharmaceutical Inc.’s revenue for fiscal 2025 (year ended December 2025) was $673.0 million, up 20.2% from fiscal 2024. In the quarter to June 2026, revenue grew 28.1%, EPS grew 23.1% and free cash flow grew 12.5%, each against the same quarter a year earlier. Revenue growth for five consecutive years.
14.54
0.63
−4.15%
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Target Price Range
Analyst price targets
Free accountTen years at a glance Fiscal years to December
| Group | Line | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Trend | 2026e | 2027e | 2028e |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Price, $ | |||||||||||||||
| Price, $ | Low | 46.52 | 43.14 | 37.44 | 35.41 | 31.99 | 72.89 | 33.36 | 31.52 | 37.02 | 18.41 |
Analyst estimates 2026–2028 Powerpack |
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| High | 110.06 | 91.35 | 90.98 | 74.50 | 179.65 | 175.00 | 88.12 | 54.98 | 60.37 | 46.50 | |||||
| People | |||||||||||||||
| People | Employees | 376 | 520 | 610 | 740 | 893 | 1,119 | 1,311 | 1,276 | 1,294 | 1,371 | ||||
| Revenue/emp, $m | 0.00 | 0.01 | 0.08 | 0.14 | 0.30 | 0.31 | 0.28 | 0.34 | 0.43 | 0.49 | |||||
| Income, $m | |||||||||||||||
| Income, $m | Revenue | 0 | 3 | 51 | 104 | 271 | 351 | 363 | 434 | 560 | 673 | ||||
| Gross margin, % | 100.00 | 99.96 | 97.77 | 91.31 | 97.74 | 95.44 | 92.21 | 89.63 | 86.25 | 83.80 | |||||
| EBT | (246) | (318) | (197) | (399) | (185) | (453) | (702) | (609) | (567) | (571) | |||||
| EBT margin, % | (184,841.35) | (12,187.52) | (382.75) | (385.14) | (68.39) | (128.91) | (193.14) | (140.32) | (101.25) | (84.84) | |||||
| Net income | (246) | (302) | (198) | (403) | (187) | (454) | (707) | (607) | (569) | (575) | |||||
| Depreciation | 8 | 8 | 17 | 2 | 13 | 20 | 21 | 13 | 23 | 31 | |||||
| Per share, $ | |||||||||||||||
| Per share, $ | Revenue | 0.00 | 0.06 | 1.03 | 1.83 | 4.45 | 5.18 | 5.20 | 5.90 | 6.19 | 6.83 | ||||
| Earnings | (6.21) | (7.12) | (3.97) | (7.12) | (3.07) | (6.70) | (10.12) | (8.25) | (6.29) | (5.83) | |||||
| Cash flow | (4.07) | (5.98) | (5.84) | (6.10) | (2.17) | (5.00) | (5.44) | (6.46) | (4.57) | (4.73) | |||||
| Capex | (0.26) | (0.07) | (0.08) | (0.44) | (0.72) | (1.08) | (2.09) | (0.64) | (0.22) | (0.21) | |||||
| Free cash flow | (4.32) | (6.05) | (5.92) | (6.54) | (2.89) | (6.07) | (7.53) | (7.10) | (4.80) | (4.94) | |||||
| Book value | 11.97 | 9.03 | 12.23 | 11.56 | 18.97 | 13.61 | 5.04 | 3.75 | 2.82 | (0.81) | |||||
| Shares, m | 40 | 42 | 50 | 57 | 61 | 68 | 70 | 74 | 91 | 99 | |||||
| Valuation, × | |||||||||||||||
| Valuation, × | P/E | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | ||||
| P/S | 0.00 | 767.05 | 42.03 | 23.30 | 31.08 | 16.22 | 8.76 | 8.16 | 6.80 | 3.37 | |||||
| P/B | 5.84 | 5.46 | 3.55 | 3.70 | 7.30 | 6.18 | 9.03 | 12.86 | 14.93 | 0.00 | |||||
| EV/Sales | 0.00 | 681.09 | 33.10 | 16.02 | 26.64 | 14.12 | 6.70 | 6.83 | 5.71 | 2.36 | |||||
| EV/FCF | (13.95) | (7.24) | (5.78) | (4.49) | (41.00) | (12.05) | (4.62) | (5.68) | (7.37) | (3.26) | |||||
| Cash, $m | |||||||||||||||
| Cash, $m | Operating cash flow | (161) | (254) | (291) | (345) | (132) | (339) | (380) | (475) | (414) | (466) | ||||
| Capex | (10) | (3) | (4) | (25) | (44) | (73) | (146) | (47) | (20) | (21) | |||||
| Free cash flow | (171) | (257) | (295) | (370) | (176) | (412) | (527) | (522) | (434) | (487) | |||||
| Balance, $m | |||||||||||||||
| Balance, $m | Working capital | 341 | 199 | 448 | 748 | 1,106 | 675 | 623 | 452 | 473 | 567 | ||||
| Total debt | — | — | — | 352 | 384 | 394 | 907 | — | — | — | |||||
| Net debt | (382) | (234) | (460) | (755) | (1,202) | (740) | (748) | (577) | (610) | (680) | |||||
| Shareholders’ equity | 474 | 383 | 609 | 654 | 1,154 | 923 | 352 | 275 | 255 | (80) | |||||
| Returns, % | |||||||||||||||
| Returns, % | ROA | (44.70) | (58.59) | (32.65) | (43.42) | (12.89) | (27.67) | (46.12) | (39.98) | (38.01) | (37.89) | ||||
| ROIC | (167.73) | (138.02) | (155.57) | 0.00 | 0.00 | (130.83) | 0.00 | 0.00 | 0.00 | 0.00 | |||||
| ROE | (48.93) | (70.48) | (39.83) | (63.79) | (20.64) | (43.72) | (110.96) | (193.34) | (214.55) | (657.14) | |||||
Negative figures in brackets.
Fiscal years to Dec 2025 · latest quarter Jun 2026
Charts ten years each
Ultragenyx Pharmaceutical Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier
| Company | Market cap | P/E | Fwd P/E | Revenue growth (Q) | EPS growth (Q) | FCF growth (Q) | Gross margin (Q) | EBIT margin (Q) | Compare |
|---|---|---|---|---|---|---|---|---|---|
| GPCR Structure Therapeutics Inc. Sponsored ADR | $1.6B | — (loss-making) | — | — | n/m | −119.15% (below 0%: shrinking) | 0.00% | 0.00% | Compare |
| QURE uniQure N.V. | $1.6B | — (loss-making) | — (loss-making) | +11.00% (above 0%: growing) | n/m | +27.66% (above 0%: growing) | 94.01% | (893.73%) | Compare |
| KRSA Korsana Biosciences, Inc. | $1.5B | — (loss-making) | — (loss-making) | −43.24% (below 0%: shrinking) | n/m | −184.69% (below 0%: shrinking) | 100.00% | 0.00% | Compare |
| MAZE Maze Therapeutics, Inc. | $1.5B | — (loss-making) | — | — | n/m | +50.21% (above 0%: growing) | 100.00% | 0.00% | Compare |
| ABSI Absci Corporation | $1.5B | — (loss-making) | — (loss-making) | −46.37% (below 0%: shrinking) | n/m | −71.74% (below 0%: shrinking) | 100.00% | (10,741.51%) | Compare |
| IMCR Immunocore Holdings PLC Sponsored ADR | $1.5B | — (loss-making) | 208× | +18.34% (above 0%: growing) | n/m | −40.74% (below 0%: shrinking) | 99.06% | (2.58%) | Compare |
| RARE Ultragenyx Pharmaceutical Inc. | $1.5B | — (loss-making) | — (loss-making) | +28.14% (above 0%: growing) | n/m | +12.50% (above 0%: growing) | 84.11% | (35.05%) | |
| ANAB AnaptysBio, Inc. | $1.5B | — (loss-making) | 220× | −7.98% (below 0%: shrinking) | n/m | −141.60% (below 0%: shrinking) | 100.00% | (135.53%) | Compare |
| RAPP Rapport Therapeutics, Inc. | $1.4B | — (loss-making) | — | — | n/m | −64.75% (below 0%: shrinking) | 100.00% | 0.00% | Compare |
| Median of peers | $1.5B | — | — | −7.98% | — | −68.24% | 100.00% | (1.29%) |
Ultragenyx Pharmaceutical Inc. (RARE) key facts
- Concern: Ultragenyx Pharmaceutical Inc. reported a net loss of $575.0 million, or a loss of $5.83 per share, for fiscal 2025.
- Strength: Ultragenyx Pharmaceutical Inc.’s revenue for fiscal 2025 (year ended December 2025) was $673.0 million, up 20.2% from fiscal 2024.
- Ultragenyx Pharmaceutical Inc. (RARE) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
- As of October 16, 2026, RARE traded at $14.54, a market capitalization of $1.5 billion.
- Trailing earnings are negative, so a P/E ratio is not meaningful; the stock trades at 2.1× sales.
- Return on equity was −657.1% and debt-to-equity 0.00.
- Its Piotroski F-score is 5 out of 9 and its Altman Z-score is −3.57 (distress zone) for fiscal 2025.