Structure Therapeutics Inc. Sponsored ADR

GPCR Healthcare Biotechnology

EPS
−36.4%
Free cash flow
−119.2%

Quarter to June 2026, against a year earlier

20.33 1.25 +6.55%
Market cap
$1.4B
P/E
0.0×
Fwd P/E
—
Dividend yield
—
F-score
n/a
Altman Z
n/a
Beneish M
n/a
Dividend safety
n/a

Insider Decisions last twelve months

Trades a month
Jan 26 Apr 26 Jul 26 Oct 26
Buy — — — — — — — — — — — —
Sell — — — — — — — — — — — —
Insider Ownership 4.39%

Capital & Financial Ratios $m

Size
Market Cap 1,360.00
Revenue ttm —
Net income ttm (214.83)
Free cash flow ttm (224.50)
Net debt Q (1,342.66)
Valuation
P/E 0.00
Forward P/E —
Price / sales 0.00
Forward P/S Powerpack
Price / FCF 0.00
Price / book 1.09
Financial health
Current ratio Q 20.75 (at or above 1.5: strong)
Debt / equity Q 0.00 (at or below 0.5: strong)
Interest coverage Q (9.73)
Growth
Revenue growth Q —
Operating income growth Q −68.39% (below 0%: shrinking)
EPS, this year −108.19% (below 0%: weak)
EPS, next year A −28.83% (below 0%: weak)
Revenue, next year A —
EPS, past 5 yrs —
EPS, next 5 yrs A −29.47% (below 0%: weak)

Green and red mark values outside typical ranges; (Q) is the latest quarter, (A) analysts’ estimates. How we judge →

Valuation vs history

P/B against its own 10 years 0.77%
10-year low 10-year high

Dividends

Yield
—
Annual rate
—
Payout ratio
—

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 467 884 1,446 1,343
Receivables — — 100 —
Inventory — — — —
Other — — — —
474 891 1,570 1,372
2023 2024 2025 Q'26
Payables 5 8 14 11
ST’ Debt — — — —
Other — — — —
25 36 63 66

Compound Annual Growth %

10y 5y 3y
Sales — — —
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — 111.85% 161.46%

Earnings Trends EPS, adjusted, against the consensus

EPS $

Mar Jun Sep Dec Year
’26 (1.05) (1.46) — — —
’25 (0.82) (1.07) (1.12) 0.52 (2.39)
’24 (0.56) (0.53) (0.59) (0.65) (2.33)
’23 (0.75) (0.61) (0.62) (0.53) (2.44)
’22 (4.33) (4.43) (3.81) (3.49) (16.06)
’21 — — — — (16.13)
Fiscal quarters ending in the months shown.

Revenue $m

Year
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 15 (120) — — —
’25 (52) (55) (51) (64) (222)
’24 (34) (26) (20) (36) (117)
’23 (20) (17) (21) (22) (79)
’22 (14) (10) (10) (12) (46)
’21 — — — (32) (32)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 14 (120) — — —
’25 (53) (55) (53) (66) (226)
’24 (34) (27) (20) (36) (118)
’23 (20) (17) (21) (23) (82)
’22 (14) (10) (11) (12) (46)
’21 — — — (33) (33)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1.1
1Buy 2 3Hold 4 5Sell

Ten years at a glance

Ten-year view Analyst estimates Powerpack
Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 TTM Jun ’26 Trend 10 yrs 2026e 2027e 2028e Next 3/yr
Income, $m
Income, $m Revenue — — — — — — — — — — — — 42 0 153 +91.4%
Gross margin, % — — — — 0.00 0.00 0.00 — — — 0.00 0.0 pt
EBT — — — — (16) (38) (51) (89) (122) (141) (214) +54.9%
EBT margin, % — — — — 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.0 pt
Net income — — — — (16) (38) (51) (90) (123) (141) (215) +54.8%
Per share, $
Per share, $ Revenue — — — — 0.00 0.00 0.00 0.00 0.00 0.00 0.00 n/m
Earnings — — — — (0.44) (16.13) (16.06) (2.44) (2.33) (2.39) (3.11) +40.2%
Cash flow — — — — (0.39) (11.85) (14.44) (2.16) (2.22) (3.75) (3.03) +57.2%
Capex — — — — 0.00 (0.44) (0.05) (0.06) (0.02) (0.06) (0.06) n/m
Free cash flow — — — — (0.39) (12.29) (14.48) (2.22) (2.24) (3.81) (3.09) +57.7%
Book value — — — — 0.97 37.67 26.55 12.33 16.43 25.61 18.64 +92.4%
Shares, m — — — — 37 3 3 37 53 59 66 +10.1%
Valuation, ×
Valuation, × P/E — — — — — — — — — — 0 —
P/S — — — — — — — — — — 0 —
P/B — — — — — — — — — — 0 —
EV/Sales — — — — — — — — — — 0 —
EV/FCF — — — — — — — — — — 0 —
Cash, $m
Cash, $m Operating cash flow — — — — (14) (32) (46) (79) (117) (222) (220) +73.1%
Capex — — — — 0 (1) 0 (2) (1) (4) (4) +185.7%
Free cash flow — — — — (14) (33) (46) (82) (118) (226) (225) +73.6%
Balance, $m
Balance, $m Working capital — — — — 35 101 80 449 855 1,507 1,306 +111.8%
Net debt — — — — (37) (107) (91) (467) (884) (1,446) (1,343) +108.0%
Shareholders’ equity — — — — 36 102 85 453 865 1,516 1,354 +111.9%
Returns, %
Returns, % ROA — — — — 0.00 (58.41) (50.56) (30.91) (17.69) (11.35) (19.17) (11.3) pt
ROIC — — — — 0.00 0.00 0.00 0.00 0.00 (157.24) (1,371.78) (157.2) pt
ROE — — — — 0.00 100.37 58.75 (53.06) (18.60) (11.86) (20.21) (11.9) pt
People
People Employees — — — — — 68 68 93 163 220 — +34.1%
Revenue/emp, $m — — — — — 0.00 0.00 0.00 0.00 0.00 — n/m
Negative figures in brackets.
estimates

All 10 years →

Fundamentals updated 26 Oct 2026

Structure Therapeutics Inc. Sponsored ADR vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
AAPG Ascentage Pharma Group International - Unsponsored ADR $1.4B — — — — +17.74% (above 0%: growing) — — Compare
OCUL Ocular Therapeutix, Inc. $1.4B — (loss-making) — (loss-making) +0.12% (above 0%: growing) n/m −25.35% (below 0%: shrinking) 85.08% (609.34%) Compare
KRSA Korsana Biosciences, Inc. $1.4B — (loss-making) — (loss-making) −43.24% (below 0%: shrinking) n/m −184.69% (below 0%: shrinking) 100.00% 0.00% Compare
GPCR Structure Therapeutics Inc. Sponsored ADR $1.4B — (loss-making) — — n/m −119.15% (below 0%: shrinking) 0.00% 0.00%
ANAB AnaptysBio, Inc. $1.4B — (loss-making) 220× −7.98% (below 0%: shrinking) n/m −141.60% (below 0%: shrinking) 100.00% (135.53%) Compare
DMRA Galecto, Inc. $1.4B 24.7× — — n/m −877.51% (below 0%: shrinking) 0.00% 0.00% Compare
MLYS Mineralys Therapeutics, Inc. $1.4B — (loss-making) — — n/m −7.91% (below 0%: shrinking) — 0.00% Compare
TSHA Taysha Gene Therapies, Inc. $1.3B — (loss-making) — (loss-making) +206.77% (above 0%: growing) n/m −100.28% (below 0%: shrinking) 100.00% 0.00% Compare
KARD KARDIGAN INC $1.3B — (loss-making) — — n/m — — 0.00% Compare
Median of peers $1.4B — — −3.93% — −100.28% 100.00% 0.00%

All 621 Biotechnology stocks →

Pay and ownership Proxy statement filed 23 April 2026

Chief executive’s pay

Year Total pay Actually paid $100 invested
2025 8.43m 36.23m 267.50
2024 5.74m 1.74m 104.31
2023 7.39m 22.06m 156.77

Ownership

Directors and executive officers, together 5.50%
Entities affiliated with FMR LLC 14.60%
Entities affiliated with Wellington Management Group LLP 10.00%
Entities affiliated with Avoro Capital Advisors LLC 9.60%
Entities affiliated with Janus Henderson Group plc 6.30%
Entities affiliated with Deep Track Capital, LP 5.80%
Total pay is as the Summary Compensation Table states it; actually paid revalues the year’s share awards at its end, as the SEC’s pay-versus-performance rule asks. $100 invested is what $100 in the company’s shares at the start of the earliest year shown was worth at each year’s end. Ownership is the proxy’s own table: the directors and officers as a group, and every holder of 5% or more. Read the proxy statement

Structure Therapeutics Inc. Sponsored ADR (GPCR) Latest News

16 Oct

21 May

Impact 4 · · biopharmadive.com

29 Mar

stockrow.com/GPCR · Data as of Oct 26, 2026 · For information only; not investment advice. · © 2026 stockrow.com