Madrigal Pharmaceuticals, Inc.

MDGL Healthcare Biotechnology

Madrigal Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $958.4 million, up 432.1% from fiscal 2024. In the quarter to June 2026, revenue grew 71.2%, EPS fell 32.9%, free cash flow grew 140.5% and total debt rose 187.9%, each against the same quarter a year earlier.

449.74 10.07 −2.19%
Market cap
$10.6B
P/E
0.0×
Fwd P/E
−71.3×
Dividend yield
—
F-score
n/a
Altman Z
10.48
Beneish M
0.50
Dividend safety
n/a

Insider Decisions trades per month

Total sells 81.48
Totals in millions of $.
Dec 25 Mar 26 Jun 26 Sep 26
Buy — — — — — — — — — — — —
Sell 3 4 9 — 6 — 2 1 1 1 1 —
Insider Ownership 26.09%

Capital & Financial Ratios $m

Market Cap 10,620.00
Revenue 1,283.94
Net Income (325.09)
Free Cash Flow (206.28)
Net Debt (498.11)
Current Ratio 3.20 (at or above 1.5: strong)
Debt/Equity 0.65
P/E ratio 0.00
Fwd P/E (71.30) (negative: loss-making)
P/S ratio 10.21 (above 10: high)
P/B ratio 25.03 (above 6: high)
Past 5Y EPS Growth —
This Y EPS Growth 53.15% (at or above 15%: strong)
Next Y EPS Growth 194.92% (at or above 15%: strong)
Next Y revenue growth 59.33% (at or above 10%: strong)
Next 5Y EPS Growth 0.00%

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/B against its own 10 years 84.62%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2025 Powerpack
2024 Powerpack
2023 Powerpack
2022 Powerpack
2021 Powerpack
2020 Powerpack
2019 Powerpack
2017 Powerpack
predictions special payouts not included in total or ratios

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 634 931 989 839
Receivables — 54 134 192
Inventory — 34 75 99
Other — — — —
637 1,033 1,246 1,199
2023 2024 2025 Q'26
Payables 28 44 49 35
ST’ Debt — — — —
Other — — — —
119 169 310 374

Compound Annual Growth %

10y 5y 3y
Sales — — (89.94%)
Cash Flow 0.00% 0.00% 0.00%
Earnings 0.00% 0.00% 0.00%
Book Value 0.00% 20.22% 45.07%

Revenue $m

Mar Jun Sep Dec Year
’26 311 364 — — —
’25 137 213 287 321 958
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (167) 23 — — —
’25 (89) (47) 80 (133) (190)
’24 (149) (135) (67) (104) (456)
’23 (84) (75) (85) (80) (324)
’22 (50) (57) (59) (59) (225)
’21 (43) (47) (46) (48) (184)
’20 (31) (24) (48) (55) (158)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (171) 19 — — —
’25 (89) (47) 76 (133) (193)
’24 (150) (140) (68) (105) (462)
’23 (84) (75) (85) (81) (326)
’22 (50) (57) (59) (59) (225)
’21 (43) (47) (46) (48) (184)
’20 (31) (24) (48) (55) (158)
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 (3.25) (1.99) — — —
’25 (2.61) (1.50) (5.08) (2.57) (12.85)
’24 (7.38) (7.10) (4.92) (2.71) (21.90)
’23 (4.23) (4.69) (5.34) (5.68) (19.99)
’22 (3.36) (4.14) (4.75) (4.98) (17.23)
’21 (3.32) (3.72) (3.79) (3.78) (14.63)
’20 (2.34) (3.18) (3.75) (3.82) (13.09)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1.1
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low 5.25 13.09 90.56 82.31 56.82 68.56 52.33 119.76 168.25 265.00

Analyst estimates 2026–2028

Powerpack
High 18.24 101.00 325.98 148.18 137.28 142.62 315.45 322.67 368.29 615.00
People
People Employees 8 8 17 29 42 71 92 376 528 915
Revenue/emp, $m 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.34 1.05
Income, $m
Income, $m Revenue — — — — — — — — 180 958
Gross margin, % 0.00 0.00 0.00 0.00 0.00 0.00 0.00 — 96.54 94.14
EBT (26) (31) (33) (84) (202) (242) (295) (374) (466) (288)
EBT margin, % 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 (258.64) (30.08)
Net income (26) (31) (33) (84) (202) (242) (295) (374) (466) (288)
Depreciation 0 0 0 0 0 0 1 3 3 6
Per share, $
Per share, $ Revenue 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 8.47 42.72
Earnings (5.07) (2.54) (2.22) (5.45) (13.09) (14.63) (17.23) (19.99) (21.90) (12.85)
Cash flow (3.38) (1.82) (1.72) (2.70) (10.20) (11.12) (13.12) (17.35) (21.42) (8.45)
Capex 0.13 (0.01) 0.00 (0.01) (0.02) (0.01) (0.01) (0.08) (0.30) (0.15)
Free cash flow (3.25) (1.83) (1.73) (2.71) (10.22) (11.14) (13.13) (17.43) (21.72) (8.60)
Book value 7.00 14.88 32.24 27.06 15.54 11.86 11.52 21.69 35.46 26.87
Shares, m 5 12 15 15 15 17 17 19 21 22
Valuation, ×
Valuation, × P/E — — — — — — — — 0.00 0.00
P/S — — — — — — — — 0.00 13.63
P/B — — — — — — — — 8.70 21.68
EV/Sales — — — — — — — — 0.00 12.95
EV/FCF — — — — — — — — (12.45) (64.00)
Cash, $m
Cash, $m Operating cash flow (18) (22) (26) (42) (158) (184) (225) (324) (456) (190)
Capex 1 0 0 0 0 0 0 (1) (6) (3)
Free cash flow (17) (22) (26) (42) (158) (184) (225) (326) (462) (193)
Balance, $m
Balance, $m Working capital 36 182 477 415 239 195 245 519 864 935
Total debt — — — 0 0 0 49 115 118 340
Net debt (40) (192) (484) (439) (284) (270) (309) (519) (814) (649)
Shareholders’ equity 36 182 477 417 240 196 197 405 754 603
Returns, %
Returns, % ROA (126.95) (26.68) (9.68) (18.10) (55.48) (86.32) (92.89) (74.49) (55.37) (25.05)
ROIC 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
ROE 422.09 (28.49) (9.95) (18.79) (61.61) (110.92) (150.12) (123.98) (80.35) (42.49)
Negative figures in brackets.

All 10 years →

Fiscal years to Dec 2025 · latest quarter Jun 2026

Charts ten years each

Madrigal Pharmaceuticals, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
CORT Corcept Therapeutics Incorporated $12.3B 212× 139× +31.74% (above 0%: growing) +21.21% (above 0%: growing) −29.89% (below 0%: shrinking) 98.41% 16.12% Compare
SMMT Summit Therapeutics PLC $12.3B — (loss-making) — (loss-making) −100.00% (below 0%: shrinking) n/m −112.80% (below 0%: shrinking) 0.00% 0.00% Compare
TECH Bio-Techne Corp $11.4B 62.0× 37.6× +1.33% (above 0%: growing) n/m −6.83% (below 0%: shrinking) 65.82% 23.13% Compare
BMRN BioMarin Pharmaceutical Inc. $10.9B 144× 16.1× +19.91% (above 0%: growing) −81.60% (below 0%: shrinking) −20.28% (below 0%: shrinking) 79.51% 11.21% Compare
MDGL Madrigal Pharmaceuticals, Inc. $10.6B — (loss-making) — (loss-making) +71.17% (above 0%: growing) n/m +140.54% (above 0%: growing) 89.02% (15.46%)
IBRX ImmunityBio, Inc. $10.6B — (loss-making) — (loss-making) +93.91% (above 0%: growing) n/m +13.38% (above 0%: growing) 99.42% (120.41%) Compare
PCVX Vaxcyte, Inc. $10.3B — (loss-making) — — n/m −92.55% (below 0%: shrinking) 0.00% 0.00% Compare
KRYS Krystal Biotech, Inc. $9.8B 38.3× 38.6× +24.14% (above 0%: growing) +39.10% (above 0%: growing) +40.14% (above 0%: growing) 94.60% 49.00% Compare
KYMR Kymera Therapeutics, Inc. $9.0B — (loss-making) — (loss-making) +466.40% (above 0%: growing) n/m +9.97% (above 0%: growing) 100.00% (116.32%) Compare
Median of peers $10.7B 103× 38.1× +24.14% +21.21% −13.55% 87.05% 5.61%

All 614 Biotechnology stocks →

Madrigal Pharmaceuticals, Inc. (MDGL) key facts

  • Strength: Madrigal Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $958.4 million, up 432.1% from fiscal 2024.
  • Madrigal Pharmaceuticals, Inc. (MDGL) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • As of October 16, 2026, MDGL traded at $449.74, a market capitalization of $10.6 billion.
  • Return on equity was −42.5% and debt-to-equity 0.65.
  • Its Altman Z-score is 10.48 (safe zone) for fiscal 2025.

Source: company filings (standardised) and stockrow calculations.

Madrigal Pharmaceuticals, Inc. (MDGL) Latest News

stockrow.com/MDGL · Data as of Jun 30, 2026 · For information only; not investment advice. · © 2026 stockrow.com