BioCryst Pharmaceuticals, Inc.

BCRX Healthcare Drug Manufacturers Specialty & Generic

BioCryst Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $874.8 million, up 94.1% from fiscal 2024. In the quarter to June 2026, revenue grew 33.6%, EPS grew 1,450.0%, free cash flow grew 153.2% and total debt rose 15.2%, each against the same quarter a year earlier. Revenue growth for five consecutive years, operating cash flow growth for three.

7.79 0.23 −2.87%
Market cap
$2.1B
P/E
0.0×
Fwd P/E
−3.5×
Dividend yield
—
F-score
7/9
Altman Z
1.83
Beneish M
−2.27
Dividend safety
n/a

Insider Decisions trades per month

Total sells 4.14
Totals in millions of $.
Dec 25 Mar 26 Jun 26 Sep 26
Buy — — — — — — — — — — — —
Sell 1 3 — — 2 — 2 — — — — —
Insider Ownership 13.68%

Capital & Financial Ratios $m

Market Cap 2,050.00
Revenue 940.61
Net Income (384.67)
Free Cash Flow 373.93
Net Debt 486.35
Current Ratio 2.32 (at or above 1.5: strong)
Debt/Equity (1.85) (negative: negative equity)
P/E ratio 0.00
Fwd P/E (3.51) (negative: loss-making)
P/S ratio 2.11
P/B ratio 0.00
Past 5Y EPS Growth —
This Y EPS Growth (289.50%) (below 0%: weak)
Next Y EPS Growth 125.20% (at or above 15%: strong)
Next Y revenue growth (18.83%) (below 0%: weak)
Next 5Y EPS Growth (18.81%) (below 0%: weak)

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/S against its own 10 years 1.88%
10-year low 10-year high
EV/Sales against its own 10 years 2.99%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2025 Powerpack
2024 Powerpack
2023 Powerpack
2022 Powerpack
2021 Powerpack
2020 Powerpack
2019 Powerpack
2017 Powerpack
predictions special payouts not included in total or ratios

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 391 321 275 353
Receivables 57 79 107 111
Inventory 29 8 5 6
Other — — — —
496 422 404 485
2023 2024 2025 Q'26
Payables 21 12 16 11
ST’ Debt 24 33 52 60
Other — — — —
150 160 196 209

Compound Annual Growth %

10y 5y 3y
Sales 33.61% 117.89% 47.82%
Cash Flow 0.00% 0.00% 0.00%
Earnings 0.00% 0.00% 0.00%
Book Value 0.00% 0.00% 0.00%

Revenue $m

Mar Jun Sep Dec Year
’26 156 218 — — —
’25 146 163 159 407 875
’24 93 109 117 132 451
’23 69 82 87 93 331
’22 50 66 76 80 271
’21 19 50 41 47 157
’20 5 3 6 4 18
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (62) 104 — — —
’25 (28) 41 42 292 347
’24 (54) (1) 8 (5) (52)
’23 (48) (19) (20) (9) (95)
’22 (78) (28) (32) (24) (162)
’21 (61) (25) (23) (32) (142)
’20 (23) (31) (38) (43) (135)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (62) 104 — — —
’25 (28) 41 40 292 345
’24 (54) (2) 8 (6) (53)
’23 (48) (19) (21) (9) (97)
’22 (78) (28) (33) (24) (163)
’21 (61) (26) (24) (34) (145)
’20 (23) (31) (38) (43) (136)
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 (2.98) 0.30 — — —
’25 0.00 0.02 0.06 1.12 1.21
’24 (0.17) (0.06) (0.07) (0.13) (0.43)
’23 (0.28) (0.40) (0.19) (0.31) (1.18)
’22 (0.40) (0.32) (0.23) (0.38) (1.33)
’21 (0.36) (0.24) (0.33) (0.10) (1.03)
’20 (0.24) (0.24) (0.26) (0.34) (1.09)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1.4
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low 1.63 3.95 4.25 1.38 1.58 7.27 7.61 4.83 4.03 6.00

Analyst estimates 2026–2028

Powerpack
High 10.24 9.25 9.71 9.95 8.99 18.48 19.99 12.08 8.88 11.31
People
People Employees 65 85 100 140 246 358 531 536 580 435
Revenue/emp, $m 0.41 0.30 0.21 0.35 0.07 0.44 0.51 0.62 0.78 2.01
Income, $m
Income, $m Revenue 26 25 21 49 18 157 271 331 451 875
Gross margin, % 91.28 95.47 100.00 92.37 91.30 95.40 97.63 98.65 97.28 97.82
EBT (55) (66) (101) (109) (183) (182) (244) (226) (87) 267
EBT margin, % (209.25) (261.18) (490.25) (222.99) (1,026.35) (115.68) (90.24) (68.26) (19.29) 30.56
Net income (55) (66) (101) (109) (183) (184) (247) (227) (89) 264
Depreciation 2 2 2 1 1 1 0 (9) (10) (3)
Per share, $
Per share, $ Revenue 0.36 0.30 0.20 0.42 0.11 0.88 1.46 1.72 2.18 4.17
Earnings (0.75) (0.78) (0.98) (0.94) (1.09) (1.03) (1.33) (1.18) (0.43) 1.26
Cash flow (0.73) (0.49) (0.90) (0.77) (0.81) (0.79) (0.87) (0.49) (0.25) 1.66
Capex (0.07) 0.00 0.00 0.00 0.00 (0.01) (0.01) (0.01) (0.01) (0.01)
Free cash flow (0.80) (0.49) (0.90) (0.78) (0.81) (0.81) (0.88) (0.51) (0.26) 1.65
Book value 0.02 0.99 0.48 0.33 (0.12) (0.60) (1.58) (2.37) (2.30) (0.57)
Shares, m 74 84 103 116 167 179 186 192 207 210
Valuation, ×
Valuation, × P/E 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 6.24
P/S 17.79 18.24 40.32 8.17 69.96 15.78 7.86 3.52 3.45 1.87
P/B 297.04 5.48 16.91 10.43 0.00 0.00 0.00 0.00 0.00 0.00
EV/Sales 16.62 14.60 36.77 6.45 68.66 16.31 9.01 4.87 4.58 2.11
EV/FCF (7.46) (8.87) (8.17) (3.50) (9.02) (17.73) (14.95) (16.58) (38.84) 5.34
Cash, $m
Cash, $m Operating cash flow (53) (41) (93) (90) (135) (142) (162) (95) (52) 347
Capex (5) 0 0 0 (1) (2) (1) (2) (1) (2)
Free cash flow (59) (41) (93) (90) (136) (145) (163) (97) (53) 345
Balance, $m
Balance, $m Working capital 13 51 45 72 218 462 411 346 262 208
Total debt 54 26 33 54 280 593 737 838 831 481
Net debt (2) (92) (73) (84) (23) 82 312 447 510 206
Shareholders’ equity 2 84 49 38 (19) (107) (295) (456) (476) (119)
Returns, %
Returns, % ROA (51.97) (49.07) (62.29) (67.61) (71.69) (39.89) (43.42) (42.46) (17.65) 52.53
ROIC 0.00 0.00 0.00 0.00 0.00 0.00 (544.24) 0.00 (4.71) 245.61
ROE (223.70) (154.16) (152.26) (248.94) (1,925.37) 291.59 123.07 60.40 19.08 (88.68)
Negative figures in brackets.

All 10 years →

Fiscal years to Dec 2025 · latest quarter Jun 2026

Charts ten years each

BioCryst Pharmaceuticals, Inc. vs peers in Drug Manufacturers Specialty & Generic (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
HCM HUTCHMED (China) Limited Sponsored ADR $2.4B — (loss-making) — +510.07% (above 0%: growing) +419.25% (above 0%: growing) +113.21% (above 0%: growing) 60.90% 0.00% Compare
PBH Prestige Consumer Healthcare Inc. $2.3B 13.9× 10.3× +6.48% (above 0%: growing) −36.46% (below 0%: shrinking) −14.19% (below 0%: shrinking) 51.25% 19.77% Compare
SUPN Supernus Pharmaceuticals, Inc. $2.3B — (loss-making) 103× +32.40% (above 0%: growing) n/m −109.26% (below 0%: shrinking) 84.63% (26.46%) Compare
PRGO Perrigo Company plc $2.3B — (loss-making) — (loss-making) −3.17% (below 0%: shrinking) n/m +18.37% (above 0%: growing) 30.69% 2.31% Compare
ALVO Alvotech $2.1B — (loss-making) 8.9× +2,310.95% (above 0%: growing) −99.51% (below 0%: shrinking) −496.58% (below 0%: shrinking) 56.47% 9.14% Compare
BCRX BioCryst Pharmaceuticals, Inc. $2.1B — (loss-making) — (loss-making) +33.61% (above 0%: growing) +1,450.00% (above 0%: growing) +153.22% (above 0%: growing) 98.24% 45.12%
XERS Xeris Biopharma Holdings, Inc. $1.8B — (loss-making) 54.5× +28.74% (above 0%: growing) n/m +8,403.09% (above 0%: growing) 86.41% 5.62% Compare
ANIP ANI Pharmaceuticals, Inc. $1.7B 14.9× 14.5× +25.87% (above 0%: growing) +194.59% (above 0%: growing) −22.19% (below 0%: shrinking) 62.35% 15.21% Compare
PAHC Phibro Animal Health Corporation $1.5B 15.8× 11.1× +4.77% (above 0%: growing) +28.57% (above 0%: growing) −35.73% (below 0%: shrinking) 33.88% 12.14% Compare
Median of peers $2.2B 14.9× 12.8× +27.31% +28.57% −18.19% 58.69% 7.38%

All 86 Drug Manufacturers Specialty & Generic stocks →

BioCryst Pharmaceuticals, Inc. (BCRX) key facts

  • Strength: BioCryst Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $874.8 million, up 94.1% from fiscal 2024.
  • BioCryst Pharmaceuticals, Inc. (BCRX) is a Drug Manufacturers Specialty & Generic company in the Healthcare sector, listed on Nasdaq.
  • Net income was $263.9 million, or $1.26 per share (basic), a net margin of 30.2%.
  • As of October 16, 2026, BCRX traded at $7.79, a market capitalization of $2.1 billion.
  • Return on equity was −88.7% and debt-to-equity -1.85.
  • Its Piotroski F-score is 7 out of 9 and its Altman Z-score is 1.83 (grey zone) for fiscal 2025.

Source: company filings (standardised) and stockrow calculations.

BioCryst Pharmaceuticals, Inc. (BCRX) Latest News

17 Mar

stockrow.com/BCRX · Data as of Jun 30, 2026 · For information only; not investment advice. · © 2026 stockrow.com