Saturday 17 October 2026
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BioCryst Pharmaceuticals, Inc.
BCRX Healthcare Drug Manufacturers Specialty & Generic
BioCryst Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $874.8 million, up 94.1% from fiscal 2024. In the quarter to June 2026, revenue grew 33.6%, EPS grew 1,450.0%, free cash flow grew 153.2% and total debt rose 15.2%, each against the same quarter a year earlier. Revenue growth for five consecutive years, operating cash flow growth for three.
7.79
0.23
−2.87%
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Target Price Range
Analyst price targets
Free accountTen years at a glance Fiscal years to December
| Group | Line | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Trend | 2026e | 2027e | 2028e |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Price, $ | |||||||||||||||
| Price, $ | Low | 1.63 | 3.95 | 4.25 | 1.38 | 1.58 | 7.27 | 7.61 | 4.83 | 4.03 | 6.00 |
Analyst estimates 2026–2028 Powerpack |
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| High | 10.24 | 9.25 | 9.71 | 9.95 | 8.99 | 18.48 | 19.99 | 12.08 | 8.88 | 11.31 | |||||
| People | |||||||||||||||
| People | Employees | 65 | 85 | 100 | 140 | 246 | 358 | 531 | 536 | 580 | 435 | ||||
| Revenue/emp, $m | 0.41 | 0.30 | 0.21 | 0.35 | 0.07 | 0.44 | 0.51 | 0.62 | 0.78 | 2.01 | |||||
| Income, $m | |||||||||||||||
| Income, $m | Revenue | 26 | 25 | 21 | 49 | 18 | 157 | 271 | 331 | 451 | 875 | ||||
| Gross margin, % | 91.28 | 95.47 | 100.00 | 92.37 | 91.30 | 95.40 | 97.63 | 98.65 | 97.28 | 97.82 | |||||
| EBT | (55) | (66) | (101) | (109) | (183) | (182) | (244) | (226) | (87) | 267 | |||||
| EBT margin, % | (209.25) | (261.18) | (490.25) | (222.99) | (1,026.35) | (115.68) | (90.24) | (68.26) | (19.29) | 30.56 | |||||
| Net income | (55) | (66) | (101) | (109) | (183) | (184) | (247) | (227) | (89) | 264 | |||||
| Depreciation | 2 | 2 | 2 | 1 | 1 | 1 | 0 | (9) | (10) | (3) | |||||
| Per share, $ | |||||||||||||||
| Per share, $ | Revenue | 0.36 | 0.30 | 0.20 | 0.42 | 0.11 | 0.88 | 1.46 | 1.72 | 2.18 | 4.17 | ||||
| Earnings | (0.75) | (0.78) | (0.98) | (0.94) | (1.09) | (1.03) | (1.33) | (1.18) | (0.43) | 1.26 | |||||
| Cash flow | (0.73) | (0.49) | (0.90) | (0.77) | (0.81) | (0.79) | (0.87) | (0.49) | (0.25) | 1.66 | |||||
| Capex | (0.07) | 0.00 | 0.00 | 0.00 | 0.00 | (0.01) | (0.01) | (0.01) | (0.01) | (0.01) | |||||
| Free cash flow | (0.80) | (0.49) | (0.90) | (0.78) | (0.81) | (0.81) | (0.88) | (0.51) | (0.26) | 1.65 | |||||
| Book value | 0.02 | 0.99 | 0.48 | 0.33 | (0.12) | (0.60) | (1.58) | (2.37) | (2.30) | (0.57) | |||||
| Shares, m | 74 | 84 | 103 | 116 | 167 | 179 | 186 | 192 | 207 | 210 | |||||
| Valuation, × | |||||||||||||||
| Valuation, × | P/E | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 6.24 | ||||
| P/S | 17.79 | 18.24 | 40.32 | 8.17 | 69.96 | 15.78 | 7.86 | 3.52 | 3.45 | 1.87 | |||||
| P/B | 297.04 | 5.48 | 16.91 | 10.43 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |||||
| EV/Sales | 16.62 | 14.60 | 36.77 | 6.45 | 68.66 | 16.31 | 9.01 | 4.87 | 4.58 | 2.11 | |||||
| EV/FCF | (7.46) | (8.87) | (8.17) | (3.50) | (9.02) | (17.73) | (14.95) | (16.58) | (38.84) | 5.34 | |||||
| Cash, $m | |||||||||||||||
| Cash, $m | Operating cash flow | (53) | (41) | (93) | (90) | (135) | (142) | (162) | (95) | (52) | 347 | ||||
| Capex | (5) | 0 | 0 | 0 | (1) | (2) | (1) | (2) | (1) | (2) | |||||
| Free cash flow | (59) | (41) | (93) | (90) | (136) | (145) | (163) | (97) | (53) | 345 | |||||
| Balance, $m | |||||||||||||||
| Balance, $m | Working capital | 13 | 51 | 45 | 72 | 218 | 462 | 411 | 346 | 262 | 208 | ||||
| Total debt | 54 | 26 | 33 | 54 | 280 | 593 | 737 | 838 | 831 | 481 | |||||
| Net debt | (2) | (92) | (73) | (84) | (23) | 82 | 312 | 447 | 510 | 206 | |||||
| Shareholders’ equity | 2 | 84 | 49 | 38 | (19) | (107) | (295) | (456) | (476) | (119) | |||||
| Returns, % | |||||||||||||||
| Returns, % | ROA | (51.97) | (49.07) | (62.29) | (67.61) | (71.69) | (39.89) | (43.42) | (42.46) | (17.65) | 52.53 | ||||
| ROIC | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | (544.24) | 0.00 | (4.71) | 245.61 | |||||
| ROE | (223.70) | (154.16) | (152.26) | (248.94) | (1,925.37) | 291.59 | 123.07 | 60.40 | 19.08 | (88.68) | |||||
Negative figures in brackets.
Fiscal years to Dec 2025 · latest quarter Jun 2026
Charts ten years each
BioCryst Pharmaceuticals, Inc. vs peers in Drug Manufacturers Specialty & Generic (Q) = latest quarter vs a year earlier
| Company | Market cap | P/E | Fwd P/E | Revenue growth (Q) | EPS growth (Q) | FCF growth (Q) | Gross margin (Q) | EBIT margin (Q) | Compare |
|---|---|---|---|---|---|---|---|---|---|
| HCM HUTCHMED (China) Limited Sponsored ADR | $2.4B | — (loss-making) | — | +510.07% (above 0%: growing) | +419.25% (above 0%: growing) | +113.21% (above 0%: growing) | 60.90% | 0.00% | Compare |
| PBH Prestige Consumer Healthcare Inc. | $2.3B | 13.9× | 10.3× | +6.48% (above 0%: growing) | −36.46% (below 0%: shrinking) | −14.19% (below 0%: shrinking) | 51.25% | 19.77% | Compare |
| SUPN Supernus Pharmaceuticals, Inc. | $2.3B | — (loss-making) | 103× | +32.40% (above 0%: growing) | n/m | −109.26% (below 0%: shrinking) | 84.63% | (26.46%) | Compare |
| PRGO Perrigo Company plc | $2.3B | — (loss-making) | — (loss-making) | −3.17% (below 0%: shrinking) | n/m | +18.37% (above 0%: growing) | 30.69% | 2.31% | Compare |
| ALVO Alvotech | $2.1B | — (loss-making) | 8.9× | +2,310.95% (above 0%: growing) | −99.51% (below 0%: shrinking) | −496.58% (below 0%: shrinking) | 56.47% | 9.14% | Compare |
| BCRX BioCryst Pharmaceuticals, Inc. | $2.1B | — (loss-making) | — (loss-making) | +33.61% (above 0%: growing) | +1,450.00% (above 0%: growing) | +153.22% (above 0%: growing) | 98.24% | 45.12% | |
| XERS Xeris Biopharma Holdings, Inc. | $1.8B | — (loss-making) | 54.5× | +28.74% (above 0%: growing) | n/m | +8,403.09% (above 0%: growing) | 86.41% | 5.62% | Compare |
| ANIP ANI Pharmaceuticals, Inc. | $1.7B | 14.9× | 14.5× | +25.87% (above 0%: growing) | +194.59% (above 0%: growing) | −22.19% (below 0%: shrinking) | 62.35% | 15.21% | Compare |
| PAHC Phibro Animal Health Corporation | $1.5B | 15.8× | 11.1× | +4.77% (above 0%: growing) | +28.57% (above 0%: growing) | −35.73% (below 0%: shrinking) | 33.88% | 12.14% | Compare |
| Median of peers | $2.2B | 14.9× | 12.8× | +27.31% | +28.57% | −18.19% | 58.69% | 7.38% |
BioCryst Pharmaceuticals, Inc. (BCRX) key facts
- Strength: BioCryst Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $874.8 million, up 94.1% from fiscal 2024.
- BioCryst Pharmaceuticals, Inc. (BCRX) is a Drug Manufacturers Specialty & Generic company in the Healthcare sector, listed on Nasdaq.
- Net income was $263.9 million, or $1.26 per share (basic), a net margin of 30.2%.
- As of October 16, 2026, BCRX traded at $7.79, a market capitalization of $2.1 billion.
- Return on equity was −88.7% and debt-to-equity -1.85.
- Its Piotroski F-score is 7 out of 9 and its Altman Z-score is 1.83 (grey zone) for fiscal 2025.