Amylyx Pharmaceuticals, Inc.

AMLX Healthcare Drug Manufacturers Specialty & Generic

Amylyx Pharmaceuticals, Inc.’s revenue for fiscal 2024 (year ended December 2024) was $87.4 million, down 77.1% from fiscal 2023.

Revenue
−100.6%
EPS
+15.2%
Free cash flow
−24.5%

Quarter to June 2026, against a year earlier

27.79 1.61 −5.48%
Market cap
$3.5B
P/E
0.0×
Fwd P/E
−9.2×
Dividend yield
—
F-score
3/9
Altman Z
−2.95
Beneish M
n/a
Dividend safety
n/a

Amylyx Pharmaceuticals, Inc. (AMLX) Operating margin

Alert me on Operating margin

Amylyx Pharmaceuticals, Inc.'s operating margin over the twelve months to 30 June 2026 was 0.00%, down 0.0 percentage points from fiscal 2025 (0.00%). Over the past ten years it has ranged from −29,013.3% (fiscal 2021) to 10.2% (fiscal 2023); the current reading is higher than 83% of that period. That is in line with the Drug Manufacturers Specialty & Generic industry median of 0.00% and in line with the Healthcare sector median of 0.00%.

Operating margin, annual

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Annual newest first

Period Operating margin Change (points)
FY2025 0.00% 360.22
FY2024 −360.2% (370.41)
FY2023 10.2% 915.91
FY2022 −905.7% 28,107.61
FY2021 −29,013.3% (23,012.56)
FY2020 −6,000.8% —

Quarterly newest first

Period Operating margin Change (points)
Jun 2026 0.00% 0.00
Mar 2026 0.00% 0.00
Dec 2025 0.00% 0.00
Sep 2025 0.00% 0.00
18 more quarters

Against its own ten years

Low −29,013.3% High 10.2%
Ten-year median −633.0%
Current reading's percentile 83

Operating margin against peers

Company Operating margin
SUPN Indivior Pharmaceuticals Inc. compare 40.6%
LQDA Liquidia Corporation compare 37.4%
PBH Prestige Consumer Healthcare Inc. compare 25.0%
TRLV Trulieve Cannabis Corp. compare 0.00%
AMLX Amylyx Pharmaceuticals, Inc. 0.00%
HCM HUTCHMED (China) Limited Sponsored ADR compare 0.00%
HIMS Hims & Hers Health, Inc. compare −5.99%
PRGO Perrigo Company plc compare −39.4%
RGC Regencell Bioscience Holdings Limited compare —
Drug Manufacturers Specialty & Generic industry median 0.00%
Healthcare sector median 0.00%
Market median 0.00%

What Operating margin is

EBIT Margin tells an investor how much operating profit, before interest and taxes, a company keeps from each unit of revenue.

EBIT ÷ Revenue

The full definition of Operating margin →

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