Saturday 17 October 2026
Export ZYME’s income statement to Excel — free account
Zymeworks Inc.
ZYME Healthcare Biotechnology
Zymeworks Inc.’s revenue for fiscal 2025 (year ended December 2025) was $106.0 million, up 38.9% from fiscal 2024. In the quarter to June 2026, revenue fell 90.6%, EPS fell 2,166.7% and free cash flow fell 385.5%, each against the same quarter a year earlier.
25.07
0.68
−2.64%
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Target Price Range
Analyst price targets
Free accountTen years at a glance Fiscal years to December
| Group | Line | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Trend | 2026e | 2027e | 2028e |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Price, $ | |||||||||||||||
| Price, $ | Low | — | 6.25 | 7.69 | 13.96 | 20.33 | 14.90 | 4.11 | 6.02 | 7.97 | 9.03 |
Analyst estimates 2026–2028 Powerpack |
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| High | — | 14.25 | 29.00 | 45.83 | 56.73 | 59.03 | 17.27 | 10.99 | 17.70 | 28.49 | |||||
| People | |||||||||||||||
| People | Employees | 117 | 147 | 183 | 256 | 355 | 458 | 294 | 277 | 286 | 264 | ||||
| Revenue/emp, $m | 0.09 | 0.35 | 0.29 | 0.12 | 0.11 | 0.06 | 1.40 | 0.27 | 0.27 | 0.40 | |||||
| Income, $m | |||||||||||||||
| Income, $m | Revenue | 11 | 52 | 53 | 30 | 39 | 27 | 412 | 76 | 76 | 106 | ||||
| Gross margin, % | (234.42) | 19.34 | (7.37) | (292.30) | (339.53) | (648.70) | 49.43 | (88.94) | (76.43) | (29.29) | |||||
| EBT | (39) | (10) | (34) | (146) | (180) | (212) | 135 | (119) | (117) | (80) | |||||
| EBT margin, % | (353.20) | (19.25) | (64.85) | (494.24) | (462.43) | (795.95) | 32.79 | (156.87) | (152.82) | (75.26) | |||||
| Net income | (34) | (10) | (37) | (145) | (181) | (212) | 124 | (119) | (123) | (81) | |||||
| Depreciation | 1 | 3 | 4 | 7 | 10 | 10 | 7 | 17 | 11 | 11 | |||||
| Per share, $ | |||||||||||||||
| Per share, $ | Revenue | 0.86 | 2.44 | 1.82 | 0.78 | 0.77 | 0.52 | 6.33 | 1.10 | 1.01 | 1.41 | ||||
| Earnings | (2.65) | (0.51) | (1.26) | (3.83) | (3.58) | (4.11) | 1.91 | (1.72) | (1.62) | (1.08) | |||||
| Cash flow | (2.77) | 0.01 | 0.83 | (2.15) | (3.01) | (3.73) | 2.21 | (1.72) | (1.45) | (0.44) | |||||
| Capex | (0.43) | (0.15) | (0.12) | (0.36) | (0.12) | (0.26) | (0.20) | (0.06) | (0.04) | (0.03) | |||||
| Free cash flow | (3.20) | (0.14) | 0.71 | (2.52) | (3.13) | (3.99) | 2.01 | (1.78) | (1.49) | (0.47) | |||||
| Book value | 5.33 | 5.48 | 6.20 | 6.46 | 8.14 | 4.83 | 7.56 | 6.75 | 4.47 | 3.56 | |||||
| Shares, m | 13 | 21 | 29 | 38 | 50 | 52 | 65 | 69 | 76 | 75 | |||||
| Valuation, × | |||||||||||||||
| Valuation, × | P/E | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 4.24 | 0.00 | 0.00 | 0.00 | ||||
| P/S | 15.62 | 3.26 | 8.05 | 58.51 | 61.13 | 31.67 | 1.19 | 9.40 | 14.55 | 18.74 | |||||
| P/B | 0.00 | 1.45 | 2.37 | 7.04 | 5.81 | 3.39 | 1.00 | 1.54 | 3.28 | 7.39 | |||||
| EV/Sales | 13.59 | 1.65 | 4.36 | 48.58 | 50.34 | 23.37 | 0.06 | 4.78 | 11.89 | 16.58 | |||||
| EV/FCF | (3.16) | (29.37) | 11.15 | (14.61) | (12.44) | (3.03) | 0.18 | (2.89) | (8.02) | (49.69) | |||||
| Cash, $m | |||||||||||||||
| Cash, $m | Operating cash flow | (35) | 0 | 24 | (82) | (151) | (192) | 144 | (118) | (110) | (33) | ||||
| Capex | (5) | (3) | (3) | (14) | (6) | (13) | (13) | (4) | (3) | (2) | |||||
| Free cash flow | (41) | (3) | 21 | (96) | (158) | (206) | 131 | (122) | (113) | (35) | |||||
| Balance, $m | |||||||||||||||
| Balance, $m | Working capital | 30 | 78 | 174 | 229 | 369 | 216 | 449 | 357 | 212 | 206 | ||||
| Total debt | 4 | 0 | 0 | 6 | 6 | 31 | 25 | — | — | — | |||||
| Net debt | (36) | (88) | (200) | (299) | (426) | (253) | (492) | (374) | (226) | (229) | |||||
| Shareholders’ equity | 68 | 116 | 180 | 246 | 410 | 249 | 493 | 465 | 339 | 269 | |||||
| Returns, % | |||||||||||||||
| Returns, % | ROA | (57.72) | (9.67) | (19.42) | (47.48) | (39.83) | (45.68) | 23.96 | (19.30) | (23.51) | (20.04) | ||||
| ROIC | (73.91) | (19.64) | 0.00 | 0.00 | 0.00 | 0.00 | 11,267.96 | (95.36) | (75.84) | (145.69) | |||||
| ROE | (248.22) | (17.42) | (24.62) | (68.25) | (55.08) | (64.29) | 33.51 | (24.78) | (30.54) | (26.72) | |||||
Negative figures in brackets.
Fiscal years to Dec 2025 · latest quarter Jun 2026
Charts ten years each
Zymeworks Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier
| Company | Market cap | P/E | Fwd P/E | Revenue growth (Q) | EPS growth (Q) | FCF growth (Q) | Gross margin (Q) | EBIT margin (Q) | Compare |
|---|---|---|---|---|---|---|---|---|---|
| MLYS Mineralys Therapeutics, Inc. | $1.9B | — (loss-making) | — | — | n/m | −7.91% (below 0%: shrinking) | — | 0.00% | Compare |
| SRPT Sarepta Therapeutics, Inc. | $1.9B | — (loss-making) | 4.4× | −34.34% (below 0%: shrinking) | n/m | −14.48% (below 0%: shrinking) | 62.77% | 3.31% | Compare |
| ZYME Zymeworks Inc. | $1.8B | — (loss-making) | 16.2× | −90.58% (below 0%: shrinking) | n/m | −385.53% (below 0%: shrinking) | (497.71%) | (918.95%) | |
| MRVI Maravai LifeSciences Holdings, Inc. | $1.8B | — (loss-making) | — (loss-making) | +8.53% (above 0%: growing) | n/m | +127.57% (above 0%: growing) | 40.14% | (29.33%) | Compare |
| PVLA Palvella Therapeutics, Inc. | $1.8B | — (loss-making) | — (loss-making) | −99.09% (below 0%: shrinking) | n/m | −136.38% (below 0%: shrinking) | 100.00% | 0.00% | Compare |
| MESO Mesoblast Limited | $1.8B | — (loss-making) | — | −13.41% (below 0%: shrinking) | n/m | −89.23% (below 0%: shrinking) | (353.35%) | (909.40%) | Compare |
| URGN Urogen Pharma | $1.8B | — (loss-making) | — (loss-making) | +199.22% (above 0%: growing) | n/m | +17.26% (above 0%: growing) | 90.93% | 0.15% | Compare |
| XNCR Xencor, Inc. | $1.8B | — (loss-making) | — (loss-making) | +17.46% (above 0%: growing) | n/m | −52.91% (below 0%: shrinking) | 100.00% | (72.37%) | Compare |
| VIR Vir Biotechnology, Inc. | $1.8B | — (loss-making) | — (loss-making) | +19,582.54% (above 0%: growing) | n/m | +200.47% (above 0%: growing) | 100.00% | 30.75% | Compare |
| Median of peers | $1.8B | — | — | +8.53% | — | −11.20% | 90.93% | 0.00% |
Zymeworks Inc. (ZYME) key facts
- Strength: Zymeworks Inc.’s revenue for fiscal 2025 (year ended December 2025) was $106.0 million, up 38.9% from fiscal 2024.
- Zymeworks Inc. (ZYME) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
- As of October 16, 2026, ZYME traded at $25.07, a market capitalization of $1.8 billion.
- Return on equity was −26.7% and debt-to-equity 0.00.
- Its Piotroski F-score is 7 out of 9 and its Altman Z-score is 11.56 (safe zone) for fiscal 2025.