Mineralys Therapeutics, Inc.

MLYS Healthcare Biotechnology

In the quarter to June 2026, EPS fell 331.8% and free cash flow fell 7.91%, each against the same quarter a year earlier. Insiders bought in the last twelve months.

20.30 1.34 −6.19%
Market cap
$1.9B
P/E
0.0×
Fwd P/E
—
Dividend yield
—
F-score
n/a
Altman Z
n/a
Beneish M
n/a
Dividend safety
n/a

Insider Decisions trades per month

Total buys 8.76
Total sells 88.00
Totals in millions of $.
Dec 25 Mar 26 Jun 26 Sep 26
Buy — — — — 1 — — — — — — —
Sell 5 — 6 3 5 4 2 5 5 2 4 —
Insider Ownership 28.19%

Capital & Financial Ratios $m

Market Cap 1,910.00
Revenue —
Net Income (349.58)
Free Cash Flow (138.79)
Net Debt (563.79)
Current Ratio 34.46 (at or above 1.5: strong)
Debt/Equity 0.18 (at or below 0.5: strong)
P/E ratio 0.00
Fwd P/E —
P/S ratio 0.00
P/B ratio 3.12
Past 5Y EPS Growth —
This Y EPS Growth (95.79%) (below 0%: weak)
Next Y EPS Growth 46.63% (at or above 15%: strong)
Next Y revenue growth —
Next 5Y EPS Growth 18.42% (at or above 15%: strong)

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/B against its own 10 years 69.66%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 237 198 657 661
Receivables — — — —
Inventory — — — —
Other — — — —
249 205 661 666
2023 2024 2025 Q'26
Payables 1 0 2 1
ST’ Debt — — — —
Other — — — —
10 15 15 19

Compound Annual Growth %

10y 5y 3y
Sales — — —
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — 0.00% 0.00%

Revenue $m

Year
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (39) (33) — — —
’25 (45) (30) (29) (38) (142)
’24 (19) (30) (50) (67) (166)
’23 (13) (20) (19) (29) (81)
’22 (7) (5) (7) (10) (29)
’21 — — (10) (5) (15)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (39) (33) — — —
’25 (45) (30) (29) (38) (142)
’24 (19) (30) (50) (67) (166)
’23 (13) (20) (19) (29) (81)
’22 (7) (5) (7) (10) (29)
’21 — — (10) (5) (15)
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 (0.47) (2.85) — — —
’25 (0.79) (0.66) (0.52) (0.40) (2.29)
’24 (0.70) (0.83) (1.13) (0.98) (3.66)
’23 (0.51) (0.31) (0.57) (0.61) (1.99)
’22 (1.48) (1.26) (1.29) (1.74) (5.77)
’21 — — — — (3.89)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1.4
1Buy 2 3Hold 4 5Sell

Ten years at a glance

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low — — — — — — — 5.85 7.95 8.24

Analyst estimates 2026–2028

Powerpack
High — — — — — — — 21.98 16.91 47.65
People
People Employees — — — — — 12 12 28 51 76
Revenue/emp, $m — — — — — 0.00 0.00 0.00 0.00 0.00
Income, $m
Income, $m Revenue — — — — — — — — — —
Gross margin, % — — — — — — — — — —
EBT — — — — (3) (19) (30) (72) (178) (155)
EBT margin, % — — — — 0.00 0.00 0.00 0.00 0.00 0.00
Net income — — — — (3) (19) (30) (72) (178) (155)
Depreciation — — — — — — — — 0 0
Per share, $
Per share, $ Revenue — — — — 0.00 0.00 0.00 0.00 0.00 0.00
Earnings — — — — (0.74) (3.89) (5.77) (1.99) (3.66) (2.29)
Cash flow — — — — (0.53) (2.92) (5.66) (2.24) (3.43) (2.10)
Capex — — — — 0.00 0.00 0.00 0.00 0.00 0.00
Free cash flow — — — — (0.53) (2.92) (5.66) (2.24) (3.43) (2.11)
Book value — — — — (0.78) (4.60) (10.12) 6.66 3.94 9.56
Shares, m — — — — 5 5 5 36 49 68
Valuation, ×
Valuation, × P/E — — — — — — — — — —
P/S — — — — — — — — — —
P/B — — — — — — — — — —
EV/Sales — — — — — — — — — —
EV/FCF — — — — — — — — — —
Cash, $m
Cash, $m Operating cash flow — — — — (2) (15) (29) (81) (166) (142)
Capex — — — — — — — — 0 0
Free cash flow — — — — (2) (15) (29) (81) (166) (142)
Balance, $m
Balance, $m Working capital — — — — (4) 6 105 239 191 646
Total debt — — — — 5 — — — — —
Net debt — — — — (1) (11) (110) (237) (198) (657)
Shareholders’ equity — — — — (4) (23) (52) 241 191 647
Returns, %
Returns, % ROA — — — — 0.00 (307.79) (47.46) (39.28) (77.72) (35.65)
ROIC — — — — 0.00 0.00 0.00 (1,153.49) 0.00 0.00
ROE — — — — 0.00 146.35 79.26 (76.13) (82.24) (36.91)
Negative figures in brackets.

All 10 years →

Charts ten years each

Mineralys Therapeutics, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
LKFT Lakefront Biotherapeutics - Sponsored ADR $2.0B — (loss-making) — (loss-making) −95.35% (below 0%: shrinking) +198.85% (above 0%: growing) +18.22% (above 0%: growing) 25.95% (982.91%) Compare
AGIO Agios Pharmaceuticals, Inc. $1.9B — (loss-making) — (loss-making) +259.25% (above 0%: growing) n/m +24.97% (above 0%: growing) 93.30% (247.07%) Compare
MLYS Mineralys Therapeutics, Inc. $1.9B — (loss-making) — — n/m −7.91% (below 0%: shrinking) — 0.00%
SRPT Sarepta Therapeutics, Inc. $1.9B — (loss-making) 4.4× −34.34% (below 0%: shrinking) n/m −14.48% (below 0%: shrinking) 62.77% 3.31% Compare
MRVI Maravai LifeSciences Holdings, Inc. $1.8B — (loss-making) — (loss-making) +8.53% (above 0%: growing) n/m +127.57% (above 0%: growing) 40.14% (29.33%) Compare
ZYME Zymeworks Inc. $1.8B — (loss-making) 16.2× −90.58% (below 0%: shrinking) n/m −385.53% (below 0%: shrinking) (497.71%) (918.95%) Compare
PVLA Palvella Therapeutics, Inc. $1.8B — (loss-making) — (loss-making) −99.09% (below 0%: shrinking) n/m −136.38% (below 0%: shrinking) 100.00% 0.00% Compare
MESO Mesoblast Limited $1.8B — (loss-making) — −13.41% (below 0%: shrinking) n/m −89.23% (below 0%: shrinking) (353.35%) (909.40%) Compare
URGN Urogen Pharma $1.8B — (loss-making) — (loss-making) +199.22% (above 0%: growing) n/m +17.26% (above 0%: growing) 90.93% 0.15% Compare
Median of peers $1.8B — — −23.87% — +1.39% 51.46% (138.20%)

All 614 Biotechnology stocks →

Mineralys Therapeutics, Inc. (MLYS) key facts

  • Mineralys Therapeutics, Inc. (MLYS) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • As of October 16, 2026, MLYS traded at $20.30, a market capitalization of $1.9 billion.
  • Return on equity was −36.9% and debt-to-equity 0.18.

Source: company filings (standardised) and stockrow calculations.

Mineralys Therapeutics, Inc. (MLYS) Latest News

18 Aug

Impact 4 · transcript
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