Mineralys Therapeutics, Inc.

MLYS Healthcare Biotechnology

EPS
−331.8%
Free cash flow
−7.91%

Quarter to June 2026, against a year earlier

15.35 0.11 +0.72%
Market cap
$1.4B
P/E
0.0×
Fwd P/E
—
Dividend yield
—
F-score
n/a
Altman Z
n/a
Beneish M
n/a
Dividend safety
n/a

Insider Decisions last twelve months

Bought, $m 8.76
Sold, $m 27.94
Trades a month
Jan 26 Apr 26 Jul 26 Oct 26
Buy — — — 1 — — — — — — — —
Sell — 6 3 5 4 2 5 5 2 4 — —
Insider Ownership 28.19%

Capital & Financial Ratios $m

Size
Market Cap 1,350.00
Revenue ttm —
Net income ttm (349.58)
Free cash flow ttm (138.79)
Net debt Q (563.79)
Valuation
P/E 0.00
Forward P/E —
Price / sales 0.00
Forward P/S Powerpack
Price / FCF 0.00
Price / book 2.36
Financial health
Current ratio Q 34.46 (at or above 1.5: strong)
Debt / equity Q 0.18 (at or below 0.5: strong)
Interest coverage Q (7.48)
Growth
Revenue growth Q —
Operating income growth Q −426.33% (below 0%: shrinking)
EPS, this year −102.11% (below 0%: weak)
EPS, next year A +47.33% (at or above 15%: strong)
Revenue, next year A —
EPS, past 5 yrs —
EPS, next 5 yrs A +11.90%

Green and red mark values outside typical ranges; (Q) is the latest quarter, (A) analysts’ estimates. How we judge →

Valuation vs history

P/B against its own 10 years 45.75%
10-year low 10-year high

Dividends

Yield
—
Annual rate
—
Payout ratio
—

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 237 198 657 661
Receivables — — — —
Inventory — — — —
Other — — — —
249 205 661 666
2023 2024 2025 Q'26
Payables 1 0 2 1
ST’ Debt — — — —
Other — — — —
10 15 15 19

Compound Annual Growth %

10y 5y 3y
Sales — — —
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — 0.00% 0.00%

Earnings Trends EPS, adjusted, against the consensus

EPS $

Mar Jun Sep Dec Year
’26 (0.47) (2.85) — — —
’25 (0.79) (0.66) (0.52) (0.40) (2.29)
’24 (0.70) (0.83) (1.13) (0.98) (3.66)
’23 (0.51) (0.31) (0.57) (0.61) (1.99)
’22 (1.48) (1.26) (1.29) (1.74) (5.77)
’21 — — — — (3.89)
Fiscal quarters ending in the months shown.

Revenue $m

Year
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (39) (33) — — —
’25 (45) (30) (29) (38) (142)
’24 (19) (30) (50) (67) (166)
’23 (13) (20) (19) (29) (81)
’22 (7) (5) (7) (10) (29)
’21 — — (10) (5) (15)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (39) (33) — — —
’25 (45) (30) (29) (38) (142)
’24 (19) (30) (50) (67) (166)
’23 (13) (20) (19) (29) (81)
’22 (7) (5) (7) (10) (29)
’21 — — (10) (5) (15)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1.4
1Buy 2 3Hold 4 5Sell

Ten years at a glance

Ten-year view Analyst estimates Powerpack
Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 TTM Jun ’26 Trend 10 yrs 2026e 2027e 2028e Next 3/yr
Income, $m
Income, $m Revenue — — — — — — — — — — — — 88 88 252 +69.3%
Gross margin, % — — — — — — — — — — — —
EBT — — — — (3) (19) (30) (72) (178) (155) (350) +114.2%
EBT margin, % — — — — 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.0 pt
Net income — — — — (3) (19) (30) (72) (178) (155) (350) +114.2%
Per share, $
Per share, $ Revenue — — — — 0.00 0.00 0.00 0.00 0.00 0.00 0.00 n/m
Earnings — — — — (0.74) (3.89) (5.77) (1.99) (3.66) (2.29) (4.24) +25.3%
Cash flow — — — — (0.53) (2.92) (5.66) (2.24) (3.43) (2.10) (1.64) +31.7%
Capex — — — — 0.00 0.00 0.00 0.00 0.00 0.00 0.00 n/m
Free cash flow — — — — (0.53) (2.92) (5.66) (2.24) (3.43) (2.11) (1.64) +31.7%
Book value — — — — (0.78) (4.60) (10.12) 6.66 3.94 9.56 6.50 n/m
Shares, m — — — — 5 5 5 36 49 68 76 +71.0%
Valuation, ×
Valuation, × P/E — — — — — — — — — — 0 —
P/S — — — — — — — — — — 0 —
P/B — — — — — — — — — — 0 —
EV/Sales — — — — — — — — — — 0 —
EV/FCF — — — — — — — — — — 0 —
Cash, $m
Cash, $m Operating cash flow — — — — (2) (15) (29) (81) (166) (142) (139) +125.1%
Capex — — — — — — — — 0 0 0 (84.4%)
Free cash flow — — — — (2) (15) (29) (81) (166) (142) (139) +125.1%
Balance, $m
Balance, $m Working capital — — — — (4) 6 105 239 191 646 646 n/m
Net debt — — — — (1) (11) (110) (237) (198) (657) (564) +241.7%
Shareholders’ equity — — — — (4) (23) (52) 241 191 647 551 n/m
Returns, %
Returns, % ROA — — — — 0.00 (307.79) (47.46) (39.28) (77.72) (35.65) (69.67) (35.6) pt
ROIC — — — — 0.00 0.00 0.00 (1,153.49) 0.00 0.00 0.00 0.0 pt
ROE — — — — 0.00 146.35 79.26 (76.13) (82.24) (36.91) (80.88) (36.9) pt
People
People Employees — — — — — 12 12 28 51 76 — +58.6%
Revenue/emp, $m — — — — — 0.00 0.00 0.00 0.00 0.00 — n/m
Negative figures in brackets.
estimates

All 10 years →

Mineralys Therapeutics, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
AAPG Ascentage Pharma Group International - Unsponsored ADR $1.4B — — — — +17.74% (above 0%: growing) — — Compare
OCUL Ocular Therapeutix, Inc. $1.4B — (loss-making) — (loss-making) +0.12% (above 0%: growing) n/m −25.35% (below 0%: shrinking) 85.08% (609.34%) Compare
KRSA Korsana Biosciences, Inc. $1.4B — (loss-making) — (loss-making) −43.24% (below 0%: shrinking) n/m −184.69% (below 0%: shrinking) 100.00% 0.00% Compare
ANAB AnaptysBio, Inc. $1.4B — (loss-making) 220× −7.98% (below 0%: shrinking) n/m −141.60% (below 0%: shrinking) 100.00% (135.53%) Compare
GPCR Structure Therapeutics Inc. Sponsored ADR $1.4B — (loss-making) — — n/m −119.15% (below 0%: shrinking) 0.00% 0.00% Compare
MLYS Mineralys Therapeutics, Inc. $1.4B — (loss-making) — — n/m −7.91% (below 0%: shrinking) — 0.00%
DMRA Galecto, Inc. $1.4B 24.7× — — n/m −877.51% (below 0%: shrinking) 0.00% 0.00% Compare
TSHA Taysha Gene Therapies, Inc. $1.3B — (loss-making) — (loss-making) +206.77% (above 0%: growing) n/m −100.28% (below 0%: shrinking) 100.00% 0.00% Compare
KARD KARDIGAN INC $1.3B — (loss-making) — — n/m — — 0.00% Compare
Median of peers $1.4B — — −3.93% — −119.15% 92.54% 0.00%

All 621 Biotechnology stocks →

Pay and ownership Proxy statement filed 8 April 2026

Ownership

Directors and executive officers, together 18.94%
Catalys Pacific Fund, LP 9.70%
Brian Taylor Slingsby, M.D., Ph.D., M.P.H. 9.70%
Entities affiliated with RA Capital Management, L.P. 9.60%
Srinivas Akkaraju, M.D., Ph.D. 7.23%
Samsara BioCapital, L.P. 7.12%
FMR LLC 6.09%
Ownership is the proxy’s own table: the directors and officers as a group, and every holder of 5% or more. Read the proxy statement

Mineralys Therapeutics, Inc. (MLYS) Latest News

18 Aug

Impact 4 · · The Motley Fool transcript

7 Jun

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