Summit Therapeutics PLC

SMMT Healthcare Biotechnology

Summit Therapeutics PLC’s revenue for fiscal 2022 (year ended December 2022) was $705,000.00. In the quarter to June 2026, EPS grew 63.2% and free cash flow fell 112.8%, each against the same quarter a year earlier. Insiders bought in the last twelve months.

14.63 0.74 −4.81%
Market cap
$12.3B
P/E
0.0×
Fwd P/E
0.0×
Dividend yield
—
F-score
3/9
Altman Z
0.88
Beneish M
−5.00
Dividend safety
n/a

Insider Decisions trades per month

Total buys 103.62
Totals in millions of $.
Dec 25 Mar 26 Jun 26 Sep 26
Buy — — — — — — — 5 — — — —
Sell — — — — — — — — — — — —
Insider Ownership 80.42%

Capital & Financial Ratios $m

Market Cap 12,260.00
Revenue 0.71
Net Income (856.09)
Free Cash Flow (459.82)
Net Debt (690.99)
Current Ratio 6.96 (at or above 1.5: strong)
Debt/Equity 0.00 (at or below 0.5: strong)
P/E ratio 0.00
Fwd P/E 0.00
P/S ratio 16,148.72 (above 10: high)
P/B ratio 18.07 (above 6: high)
Past 5Y EPS Growth —
This Y EPS Growth 19.42% (at or above 15%: strong)
Next Y EPS Growth 2.38%
Next Y revenue growth 38.01% (at or above 10%: strong)
Next 5Y EPS Growth 21.71% (at or above 15%: strong)

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/S against its own 10 years 79.76%
10-year low 10-year high
P/B against its own 10 years 68.66%
10-year low 10-year high
EV/Sales against its own 10 years 78.77%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2023 Powerpack
2022 Powerpack
2021 Powerpack
special payouts not included in total or ratios

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 186 413 714 691
Receivables 3 11 7 30
Inventory — — — —
Other — — — —
190 424 720 721
2023 2024 2025 Q'26
Payables 3 5 20 23
ST’ Debt — — — —
Other 1 2 2 3
20 42 73 104

Compound Annual Growth %

10y 5y 3y
Sales — (46.49%) (1.73%)
Cash Flow 0.00% 0.00% 0.00%
Earnings 0.00% 0.00% 0.00%
Book Value 0.00% 52.66% 73.27%

Revenue $m

Mar Jun Sep Dec Year
’26 — — — — —
’22 0 0 0 0 1
’21 0 0 1 0 2
’20 0 0 0 0 1
’19 — — 0 0 1
’19 — — — — 57
’18 — — — — 16
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (122) (141) — — —
’25 (61) (67) (93) (102) (323)
’24 (30) (33) (30) (49) (142)
’23 (13) (29) (15) (19) (77)
’22 (19) (19) (9) 5 (42)
’21 (21) (19) (24) (9) (73)
’20 (5) (19) (17) (8) (48)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (123) (142) — — —
’25 (62) (67) (93) (102) (324)
’24 (30) (33) (30) (49) (142)
’23 (13) (29) (15) (19) (77)
’22 (19) (20) (9) 5 (42)
’21 (21) (19) (24) (9) (73)
’20 (5) (19) (17) (8) (49)
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 (0.24) (0.28) — — —
’25 (0.09) (0.76) (0.31) (0.29) (1.44)
’24 (0.06) (0.09) (0.08) (0.08) (0.31)
’23 (1.43) (0.02) (0.03) (0.05) (0.99)
’22 (0.15) (0.12) (0.10) (0.07) (0.41)
’21 (0.21) (0.27) (0.20) (0.28) (0.67)
’20 (0.09) (0.23) (0.26) (0.18) (0.76)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1.7
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low 4.26 8.24 1.12 1.10 1.18 2.23 0.66 1.25 2.10 15.55

Analyst estimates 2026–2028

Powerpack
High 19.75 16.86 15.90 2.46 6.14 12.30 5.61 5.78 33.89 36.91
People
People Employees 37 40 60 61 81 110 77 105 159 265
Revenue/emp, $m 0.00 0.00 0.00 0.00 0.01 0.02 0.01 0.00 0.00 0.00
Income, $m
Income, $m Revenue 1 3 16 1 1 2 1 — — —
Gross margin, % 0.00 0.00 0.00 100.00 100.00 100.00 100.00 — — —
EBT (35) (34) (31) (29) (53) (89) (79) (615) (221) (1,080)
EBT margin, % (3,925.57) (1,109.63) (193.97) (3,915.34) (6,152.33) (4,897.84) (11,174.75) 0.00 0.00 0.00
Net income (31) (28) (26) (29) (53) (89) (79) (615) (221) (1,080)
Depreciation 0 0 0 2 2 2 3 0 0 0
Per share, $
Per share, $ Revenue 0.01 0.02 0.08 0.02 0.01 0.01 0.00 0.00 0.00 0.00
Earnings (0.52) (0.47) (0.40) (0.92) (0.76) (0.67) (0.41) (0.99) (0.31) (1.44)
Cash flow (0.15) 0.09 (0.10) (0.63) (0.69) (0.55) (0.22) (0.12) (0.20) (0.43)
Capex 0.00 0.00 0.00 (0.01) (0.01) 0.00 0.00 0.00 0.00 0.00
Free cash flow (0.15) 0.09 (0.10) (0.64) (0.70) (0.55) (0.22) (0.12) (0.20) (0.43)
Book value 0.13 (0.02) (0.02) 2.40 1.14 0.63 0.66 0.13 0.54 0.88
Shares, m 179 187 199 33 70 132 193 620 719 748
Valuation, ×
Valuation, × P/E 0.00 0.00 0.00 0.00 0.00 0.00 0.00 — — —
P/S 0.00 47.96 0.57 92.88 379.96 195.86 1,371.18 — — —
P/B 78.42 6.91 0.52 0.67 4.11 4.25 7.63 — — —
EV/Sales 0.00 34.25 0.06 (19.12) 302.81 156.22 1,152.64 — — —
EV/FCF 2.84 (8.55) (0.07) 0.23 (5.35) (3.87) (19.17) — — —
Cash, $m
Cash, $m Operating cash flow (26) 16 (19) (21) (48) (73) (42) (77) (142) (323)
Capex 0 0 (1) 0 0 0 (1) 0 0 (1)
Free cash flow (26) 16 (19) (21) (49) (73) (42) (77) (142) (324)
Balance, $m
Balance, $m Working capital 25 28 19 66 68 72 618 169 382 647
Total debt — — — 0 0 — 495 100 — —
Net debt (23) (35) (29) (63) (66) (72) (154) (86) (413) (714)
Shareholders’ equity 23 (4) (5) 79 79 83 127 78 389 659
Returns, %
Returns, % ROA (83.12) (58.39) (35.72) (33.19) (53.03) (82.09) (20.26) (141.83) (69.32) (181.94)
ROIC 0.00 0.00 0.00 (111.17) (253.57) (468.69) 0.00 0.00 0.00 0.00
ROE (111.44) 628.29 (630.66) (43.05) (66.57) (108.89) (75.05) (601.85) (94.90) (206.10)
Negative figures in brackets.

All 10 years →

Fiscal years to Dec 2022 · latest quarter Dec 2022

Charts ten years each

Summit Therapeutics PLC vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
JAZZ Jazz Pharmaceuticals PLC $13.9B 13.8× 17.3× +15.55% (above 0%: growing) n/m +140.99% (above 0%: growing) 90.37% 20.54% Compare
HALO Halozyme Therapeutics, Inc. $13.8B 34.6× 10.6× +47.67% (above 0%: growing) +44.12% (above 0%: growing) +141.18% (above 0%: growing) 83.54% 59.80% Compare
BBIO BridgeBio Pharma, Inc. $13.1B — (loss-making) — (loss-making) +120.39% (above 0%: growing) n/m +16.59% (above 0%: growing) 93.83% (43.94%) Compare
SMMT Summit Therapeutics PLC $12.3B — (loss-making) — (loss-making) −100.00% (below 0%: shrinking) n/m −112.80% (below 0%: shrinking) 0.00% 0.00%
CORT Corcept Therapeutics Incorporated $12.3B 212× 139× +31.74% (above 0%: growing) +21.21% (above 0%: growing) −29.89% (below 0%: shrinking) 98.41% 16.12% Compare
TECH Bio-Techne Corp $11.4B 62.0× 37.6× +1.33% (above 0%: growing) n/m −6.83% (below 0%: shrinking) 65.82% 23.13% Compare
BMRN BioMarin Pharmaceutical Inc. $10.9B 144× 16.1× +19.91% (above 0%: growing) −81.60% (below 0%: shrinking) −20.28% (below 0%: shrinking) 79.51% 11.21% Compare
MDGL Madrigal Pharmaceuticals, Inc. $10.6B — (loss-making) — (loss-making) +71.17% (above 0%: growing) n/m +140.54% (above 0%: growing) 89.02% (15.46%) Compare
IBRX ImmunityBio, Inc. $10.6B — (loss-making) — (loss-making) +93.91% (above 0%: growing) n/m +13.38% (above 0%: growing) 99.42% (120.41%) Compare
Median of peers $11.8B 62.0× 17.3× +39.71% +21.21% +14.98% 89.69% 13.67%

All 614 Biotechnology stocks →

Summit Therapeutics PLC (SMMT) key facts

  • Summit Therapeutics PLC (SMMT) is a Biotechnology company in the Healthcare sector, traded in the US as an ADR.
  • Summit Therapeutics PLC’s revenue for fiscal 2022 (year ended December 2022) was $705,000.00.
  • As of October 16, 2026, SMMT traded at $14.63, a market capitalization of $12.3 billion.
  • Return on equity was −206.1% and debt-to-equity 0.00.
  • Its Piotroski F-score is 3 out of 9 and its Altman Z-score is 0.88 (distress zone) for fiscal 2022.

Source: company filings (standardised) and stockrow calculations.

Summit Therapeutics PLC (SMMT) Latest News

stockrow.com/SMMT · Data as of Dec 31, 2022 · For information only; not investment advice. · © 2026 stockrow.com