stockrowRhythm Pharmaceuticals, Inc.
RYTM Healthcare Biotechnology
Rhythm Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $189.8 million, up 45.8% from fiscal 2024.
- Revenue
- +79.6%
- EPS
- +26.9%
- Free cash flow
- +95.4%
Quarter to September 2026, against a year earlier
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Rhythm Pharmaceuticals, Inc. (RYTM) Operating margin
Rhythm Pharmaceuticals, Inc.'s operating margin over the twelve months to 30 September 2026 was −66.7%, up 34.5 percentage points from fiscal 2025 (−101.2%). Over the past ten years it has ranged from −5,391.9% (fiscal 2021) to 0.00% (fiscal 2020); the current reading is higher than 45% of that period. That is below the Biotechnology industry median of 0.00% and below the Healthcare sector median of 0.00%.
Operating margin, annual
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Annual newest first
| Period | Operating margin | Change (points) |
|---|---|---|
| FY2025 | −101.2% | 102.85 |
| FY2024 | −204.0% | 34.06 |
| FY2023 | −238.1% | 519.82 |
| FY2022 | −757.9% | 4,633.93 |
| FY2021 | −5,391.9% | (5,391.85) |
| FY2020 | 0.00% | 0.00 |
| FY2019 | 0.00% | 0.00 |
| FY2018 | 0.00% | 0.00 |
| FY2017 | 0.00% | 0.00 |
| FY2016 | 0.00% | 0.00 |
Quarterly newest first
| Period | Operating margin | Change (points) |
|---|---|---|
| Sep 2026 | −42.6% | 25.51 |
| Jun 2026 | −68.1% | 18.97 |
| Mar 2026 | −87.1% | (4.91) |
| Dec 2025 | −82.2% | 20.44 |
| 36 more quarters | Free account |
Against its own ten years
Operating margin against peers
| Company | Operating margin |
|---|---|
| CORT Corcept Therapeutics Incorporated compare | 11.5% |
| ORKA Oruka Therapeutics, Inc. compare | 0.00% |
| PRAX Praxis Precision Medicines, Inc. compare | 0.00% |
| ABVX Abivax SA Sponsored ADR compare | 0.00% |
| AXSM Axsome Therapeutics, Inc. compare | −17.5% |
| ARWR Arrowhead Pharmaceuticals, Inc. compare | −33.8% |
| RYTM Rhythm Pharmaceuticals, Inc. | −66.7% |
| IONS Ionis Pharmaceuticals, Inc. compare | −68.0% |
| CYTK Cytokinetics, Incorporated compare | −625.2% |
| Biotechnology industry median | 0.00% |
| Healthcare sector median | 0.00% |
| Market median | 0.00% |
What Operating margin is
EBIT Margin tells an investor how much operating profit, before interest and taxes, a company keeps from each unit of revenue.
EBIT ÷ Revenue
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