Rhythm Pharmaceuticals, Inc.
RYTM Healthcare Biotechnology
Rhythm Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $189.8 million, up 45.8% from fiscal 2024. In the quarter to June 2026, revenue grew 46.9%, EPS grew 2.67% and free cash flow grew 60.7%, each against the same quarter a year earlier. Revenue growth for three consecutive years.
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Rhythm Pharmaceuticals, Inc. (RYTM) Piotroski F-score
Rhythm Pharmaceuticals, Inc.'s Piotroski F-score for fiscal 2025 is 6 out of 9: 6 of nine tests of profitability, leverage and efficiency passed, up from 4 in fiscal 2024.
Piotroski F-score, annual
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Annual newest first
| Period | Piotroski F-score | Change (points) |
|---|---|---|
| FY2025 | 6 | 2.00 |
| FY2024 | 4 | 1.00 |
| FY2023 | 3 | — |
How fiscal 2025’s score is made up
| Test | This year | Year before | Result | Points |
|---|---|---|---|---|
| Positive return on assets | (46.29%) | (72.98%) | Fail | 0 |
| Positive operating cash flow | (115.67m) | (113.88m) | Fail | 0 |
| Rising return on assets | (46.29%) | (72.98%) | Pass | 1 |
| Cash flow above net income | 86.24m | 150.69m | Pass | 1 |
| Falling long-term leverage | 0.00 | 0.00 | Pass | 1 |
| Rising current ratio | 4.41 | 3.24 | Pass | 1 |
| No new shares issued | 64,984,000 | 60,995,000 | Fail | 0 |
| Rising gross margin | 89.73% | 89.73% | Pass | 1 |
| Rising asset turnover | 0.43 | 0.36 | Pass | 1 |
| Piotroski F-score | Mixed | 6 | ||
How the Piotroski F-score works
One point for each of nine tests, this fiscal year against the one before: positive return on assets, positive operating cash flow, rising return on assets, cash flow above net income, falling long-term leverage, a rising current ratio, no new shares issued, a rising gross margin and rising asset turnover. The ratios are the ones on this site, so each can be checked.
Joseph Piotroski (2000) called 8–9 high and 0–1 low; reading it in three bands is the common convention:
| 7–9 | Strong — most fundamentals improved |
|---|---|
| 4–6 | Mixed |
| 0–3 | Weak — most fundamentals deteriorated |
Where this differs from the paper: return on assets is on average rather than beginning-of-year assets, and weighted basic shares stand in for shares issued. The score is shown only when all nine tests can be worked out, which takes three fiscal years; banks and insurers, which report no current assets or gross profit, have none.
Piotroski F-score against peers
| Company | Piotroski F-score |
|---|---|
| RYTM Rhythm Pharmaceuticals, Inc. | 6 |
| LGND Ligand Pharmaceuticals Incorporated compare | 6 |
| MIRM Mirum Pharmaceuticals, Inc. compare | 6 |
| IOVA Iovance Biotherapeutics, Inc. compare | 4 |
| CGON CG Oncology, Inc. compare | 2 |
| KOD Kodiak Sciences Inc. compare | — |
| PRAX Praxis Precision Medicines, Inc. compare | — |
| IMVT Immunovant, Inc. compare | — |
| BLTE Belite Bio, Inc. Sponsored ADR compare | — |
What Piotroski F-score is
The Piotroski F-Score tells an investor how many signs of improving profitability, funding and efficiency a company shows against a year earlier.
One point for each of nine tests against a year earlier: positive return on assets, positive operating cash flow, rising return on assets, cash flow above net income, falling long-term leverage, rising current ratio, no new shares issued, rising gross margin, and rising asset turnover