Twist Bioscience Corporation

TWST Healthcare Biotechnology

Twist Bioscience Corporation’s revenue for fiscal 2025 (year ended September 2025) was $376.6 million, up 20.3% from fiscal 2024.

Revenue
+23.2%
EPS
−264.7%
Free cash flow
−7.23%
Total debt
0.00%

Quarter to June 2026, against a year earlier

120.82 0.21 +0.17%
Market cap
$7.9B
P/E
0.0×
Fwd P/E
−91.4×
Dividend yield
—
F-score
4/9
Altman Z
3.44
Beneish M
−2.30
Dividend safety
n/a

Twist Bioscience Corporation (TWST) Operating margin

Alert me on Operating margin

Twist Bioscience Corporation's operating margin over the twelve months to 30 June 2026 was −33.6%, up 2.6 percentage points from fiscal 2025 (−36.2%). Over the past ten years it has ranged from −1,924.0% (fiscal 2016) to −36.2% (fiscal 2025) — the current reading is the highest in ten years. That is below the Biotechnology industry median of 0.00% and below the Healthcare sector median of 0.00%.

Operating margin, annual

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Annual newest first

Period Operating margin Change (points)
FY2025 −36.2% 34.38
FY2024 −70.6% 18.04
FY2023 −88.6% 26.73
FY2022 −115.3% 0.08
FY2021 −115.4% 40.06
FY2020 −155.5% 44.68
FY2019 −200.2% 77.35
FY2018 −277.5% 265.66
FY2017 −543.2% 1,380.86
FY2016 −1,924.0% —

Quarterly newest first

Period Operating margin Change (points)
Jun 2026 −30.7% 10.77
Mar 2026 −41.4% (9.69)
Dec 2025 −31.7% (1.50)
Sep 2025 −30.2% 1.13
31 more quarters

Against its own ten years

Low −1,924.0% High −36.2%
Ten-year median −135.4%
Current reading's percentile 100

Operating margin against peers

Company Operating margin
KRYS Krystal Biotech, Inc. compare 48.4%
PTGX Protagonist Therapeutics, Inc. compare 20.7%
TGTX TG Therapeutics, Inc. compare 17.1%
CAI Caris Life Sciences,�Inc. compare 13.4%
SYRE Spyre Therapeutics, Inc. compare 0.00%
MDGL Madrigal Pharmaceuticals, Inc. compare −10.7%
TWST Twist Bioscience Corporation −33.6%
IBRX ImmunityBio, Inc. compare −151.9%
CYTK Cytokinetics, Incorporated compare −625.2%
Biotechnology industry median 0.00%
Healthcare sector median 0.00%
Market median 0.00%

What Operating margin is

EBIT Margin tells an investor how much operating profit, before interest and taxes, a company keeps from each unit of revenue.

EBIT ÷ Revenue

The full definition of Operating margin →

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