Rhythm Pharmaceuticals, Inc.

RYTM Healthcare Biotechnology

Rhythm Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $189.8 million, up 45.8% from fiscal 2024.

Revenue
+79.6%
EPS
+26.9%
Free cash flow
+95.4%

Quarter to September 2026, against a year earlier

111.29 6.27 +5.97%
Market cap
$7.3B
P/E
0.0×
Fwd P/E
−31.6×
Dividend yield
—
F-score
6/9
Altman Z
15.89
Beneish M
−2.93
Dividend safety
n/a

Rhythm Pharmaceuticals, Inc. (RYTM) Return on equity

Alert me on Return on equity

Rhythm Pharmaceuticals, Inc.'s return on equity over the twelve months to 30 September 2026 was −167.5%, up 83.6 percentage points from fiscal 2025 (−251.1%). Over the past ten years it has ranged from −276.3% (fiscal 2024) to 142.9% (fiscal 2016); the current reading is higher than 18% of that period. That is below the Biotechnology industry median of −50.1% and below the Healthcare sector median of −26.3%.

Return on equity, annual

Embed this chart

Annual newest first

Period Return on equity Change (points)
FY2025 −251.1% 25.19
FY2024 −276.3% (191.23)
FY2023 −85.1% (19.05)
FY2022 −66.1% (35.16)
FY2021 −30.9% 28.99
FY2020 −59.9% (6.50)
FY2019 −53.4% (15.50)
FY2018 −37.9% 29.18
FY2017 −67.1% (209.92)
FY2016 142.9% 83.89

Against its own ten years

Low −276.3% High 142.9%
Ten-year median −59.9%
Current reading's percentile 18

Return on equity against peers

Company Return on equity
CYTK Cytokinetics, Incorporated compare 184.7%
CORT Corcept Therapeutics Incorporated compare 21.7%
ORKA Oruka Therapeutics, Inc. compare −18.3%
PRAX Praxis Precision Medicines, Inc. compare −38.9%
ARWR Arrowhead Pharmaceuticals, Inc. compare −64.9%
IONS Ionis Pharmaceuticals, Inc. compare −105.5%
RYTM Rhythm Pharmaceuticals, Inc. −167.5%
AXSM Axsome Therapeutics, Inc. compare −175.6%
ABVX Abivax SA Sponsored ADR compare −249.8%
Biotechnology industry median −50.1%
Healthcare sector median −26.3%
Market median 0.51%

What Return on equity is

ROE shows how much profit a company earns for its shareholders on the equity they have in the business.

Annual: Net Income Allotted to Shareholders ÷ Average Common Equity; TTM: Net Income Allotted to Shareholders ÷ Average Common Equity (latest quarter)

The full definition of Return on equity →

More on RYTM