stockrowAxsome Therapeutics, Inc.
AXSM Healthcare Biotechnology
Axsome Therapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $638.5 million, up 65.5% from fiscal 2024.
- Revenue
- +51.9%
- EPS
- +73.9%
- Free cash flow
- −1,078.3%
- Total debt
- +4.04%
Quarter to September 2026, against a year earlier
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Axsome Therapeutics, Inc. (AXSM) Operating margin
Axsome Therapeutics, Inc.'s operating margin over the twelve months to 30 September 2026 was −17.5%, up 8.7 percentage points from fiscal 2025 (−26.1%). Over the past ten years it has ranged from −359.3% (fiscal 2022) to 0.00% (fiscal 2021); the current reading is higher than 36% of that period. That is below the Biotechnology industry median of 0.00% and below the Healthcare sector median of 0.00%.
Operating margin, annual
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Annual newest first
| Period | Operating margin | Change (points) |
|---|---|---|
| FY2025 | −26.1% | 46.62 |
| FY2024 | −72.7% | 12.93 |
| FY2023 | −85.7% | 273.66 |
| FY2022 | −359.3% | (359.33) |
| FY2021 | 0.00% | 0.00 |
| FY2020 | 0.00% | 0.00 |
| FY2019 | 0.00% | 0.00 |
| FY2018 | 0.00% | 0.00 |
| FY2017 | 0.00% | 0.00 |
| FY2016 | 0.00% | 0.00 |
Quarterly newest first
| Period | Operating margin | Change (points) |
|---|---|---|
| Sep 2026 | −4.26% | 18.47 |
| Jun 2026 | −22.7% | 10.41 |
| Mar 2026 | −33.1% | (19.39) |
| Dec 2025 | −13.8% | 13.22 |
| 43 more quarters | Free account |
Against its own ten years
Operating margin against peers
| Company | Operating margin |
|---|---|
| LGND Ligand Pharmaceuticals Incorporated compare | 9.29% |
| ORKA Oruka Therapeutics, Inc. compare | 0.00% |
| PRAX Praxis Precision Medicines, Inc. compare | 0.00% |
| ABVX Abivax SA Sponsored ADR compare | 0.00% |
| BLTE Belite Bio, Inc. Sponsored ADR compare | 0.00% |
| AXSM Axsome Therapeutics, Inc. | −17.5% |
| RYTM Rhythm Pharmaceuticals, Inc. compare | −66.7% |
| IONS Ionis Pharmaceuticals, Inc. compare | −68.0% |
| MIRM Mirum Pharmaceuticals, Inc. compare | −133.6% |
| Biotechnology industry median | 0.00% |
| Healthcare sector median | 0.00% |
| Market median | 0.00% |
What Operating margin is
EBIT Margin tells an investor how much operating profit, before interest and taxes, a company keeps from each unit of revenue.
EBIT ÷ Revenue
More on AXSM
- Revenue
- Net income
- EPS (diluted)
- EBITDA
- Free cash flow
- Operating cash flow
- Gross margin
- Net margin
- Free cash flow margin
- P/E ratio
- P/S ratio
- P/B ratio
- Price to free cash flow
- EV/EBITDA
- EV/Sales
- EV/FCF
- Return on equity
- Return on assets
- Return on invested capital
- Debt to equity
- Current ratio
- Total debt
- Shares outstanding
- Book value per share
- Revenue growth
- Altman Z-score
- Beneish M-score
- The full statement