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Axsome Therapeutics, Inc. (AXSM) vs Rhythm Pharmaceuticals, Inc. (RYTM)

Axsome Therapeutics, Inc. and Rhythm Pharmaceuticals, Inc. are both Biotechnology companies. Axsome Therapeutics, Inc. and Rhythm Pharmaceuticals, Inc. are of similar size ($7.3B and $6.8B). Rhythm Pharmaceuticals, Inc. grew revenue faster over the last twelve months: 61.0% against 54.2%. Axsome Therapeutics, Inc. has the higher net margin (−18.2% vs −70.6%) and the higher return on invested capital (0.00% vs 0.00%). Across the 16 metrics below, Axsome Therapeutics, Inc. leads on 12 and Rhythm Pharmaceuticals, Inc. on 4.

Valuation

Metric AXSM RYTM Biotechnology median
P/E n/m n/m 10.26
P/S 7.83 25.49 9.18
P/B 64.25 81.36 2.05
Price to free cash flow n/m n/m 24.81
EV/EBITDA n/m n/m 0.65
EV/Sales 7.61 24.35 8.98
Earnings yield (2.37%) (2.79%) (34.89%)
Free cash flow yield (1.22%) (1.78%) (24.52%)

Profitability

Metric AXSM RYTM Biotechnology median
Gross margin 93.25% 88.23% 65.16%
Operating margin (17.45%) (66.70%) 0.00%
Net margin (18.18%) (70.63%) 0.00%
Free cash flow margin (9.55%) (29.13%) 0.00%
Return on equity (175.59%) (167.49%) (50.12%)
Return on assets (21.03%) (41.75%) (45.60%)
Return on invested capital 0.00% 0.00% 0.00%

Growth

Metric AXSM RYTM Biotechnology median
Revenue growth (TTM) 54.16% 61.04% 6.26%
EPS growth (last fiscal year) 38.56% 28.34% 29.88%
Revenue growth, 5-year CAGR — — 9.75%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric AXSM RYTM Biotechnology median
Debt to equity 1.21 0.00 0.00
Current ratio 1.42 2.78 4.89
Net debt to EBITDA 1.29 2.04 1.01

Dividend

Metric AXSM RYTM Biotechnology median
Dividend yield — — 0.41%
Payout ratio — — —

Size

Metric AXSM RYTM Biotechnology median
Market cap 6.83b 7.28b 172.11m

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