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Friday 6 November 2026 Export IONS’s income statement to Excel — free account

Ionis Pharmaceuticals, Inc.

IONS Healthcare Biotechnology

Ionis Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $943.7 million, up 33.8% from fiscal 2024.

Revenue
−40.7%
EPS
−188.5%
Free cash flow
+299.3%
Total debt
+116.0%

Quarter to June 2026, against a year earlier

39.48 0.68 +1.75%
Market cap
$6.5B
P/E
0.0×
Fwd P/E
−12.2×
Dividend yield
—
F-score
4/9
Altman Z
2.12
Beneish M
−3.13
Dividend safety
n/a
Overview Business Profile
Financials
Income Statement Balance Sheet Cash Flow Metrics & Ratios
Segments Valuation Filings

Ionis Pharmaceuticals, Inc. (IONS) EV/Sales

Alert me on EV/Sales

As of 6 November 2026, Ionis Pharmaceuticals, Inc. (IONS) trades at a EV/Sales of 7.2×. Over the past ten years it has ranged from 3.7× (March 2020) to 40.4× (March 2015); the current reading is higher than 35% of that period. That is below the Biotechnology industry median of 9.0× and above the Healthcare sector median of 3.5×.

EV/Sales, daily

Embed this chart

Annual newest first

Period EV/Sales Change
FY2025 12.5× 108.26%
FY2024 6.0× (27.64%)
FY2023 8.3× 7.11%
FY2022 7.7× 83.57%
FY2021 4.2× (55.81%)
FY2020 9.5× 58.40%
FY2019 6.0× (36.96%)
FY2018 9.5× (13.91%)
FY2017 11.1× (25.99%)
FY2016 15.0× (40.58%)

Quarterly newest first

Period EV/Sales Change
Jun 2026 14.7× 27.02%
Mar 2026 11.6× (7.16%)
Dec 2025 12.5× 36.13%
Sep 2025 9.2× 85.16%
42 more quarters

Against its own ten years

Low 3.7× High 40.4×
Ten-year median 8.9×
Current reading's percentile 37

EV/Sales against peers

Company EV/Sales
BLTE Belite Bio, Inc. Sponsored ADR compare n/m
IMVT Immunovant, Inc. compare n/m
ORKA Oruka Therapeutics, Inc. compare n/m
KOD Kodiak Sciences Inc. compare n/m
IONS Ionis Pharmaceuticals, Inc. 7.0×
AXSM Axsome Therapeutics, Inc. compare 7.6×
MIRM Mirum Pharmaceuticals, Inc. compare 9.7×
LGND Ligand Pharmaceuticals Incorporated compare 24.7×
CGON CG Oncology, Inc. compare 755×
Biotechnology industry median 9.0×
Healthcare sector median 3.5×
Market median 2.1×

What EV/Sales is

EV/Sales tells an investor how the value of a whole company, counting its debt and cash, compares with the sales it brings in.

((Stock Price × Shares (Basic, Weighted) (latest quarter)) + (Long Term Debt (Total) (latest quarter) + Current Part of Debt (latest quarter)) − Cash & Short Term Investments (latest quarter)) ÷ Revenue (TTM)

The full definition of EV/Sales →

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