Ionis Pharmaceuticals, Inc.

IONS Healthcare Biotechnology

Ionis Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $943.7 million, up 33.8% from fiscal 2024.

Revenue
−40.7%
EPS
−188.5%
Free cash flow
+299.3%
Total debt
+116.0%

Quarter to June 2026, against a year earlier

39.48 0.68 +1.75%
Market cap
$6.5B
P/E
0.0×
Fwd P/E
−12.2×
Dividend yield
—
F-score
4/9
Altman Z
2.12
Beneish M
−3.13
Dividend safety
n/a

Ionis Pharmaceuticals, Inc. (IONS) EPS (diluted)

Alert me on EPS (diluted)

Ionis Pharmaceuticals, Inc.'s EPS (diluted) for fiscal 2025 was −$2.38, compared with −$3.04 in fiscal 2024. Over the twelve months to 30 June 2026 it was −$3.46. Over the past ten years it has ranged from −$3.23 (fiscal 2020) to $2.07 (fiscal 2018); the current reading is higher than 36% of that period. Ionis Pharmaceuticals, Inc. ranks 399th of 580 Biotechnology companies by EPS (diluted).

EPS (diluted), annual

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Annual newest first

Period EPS (diluted) Change
FY2025 −$2.38 —
FY2024 −$3.04 —
FY2023 −$2.56 —
FY2022 −$1.90 —
FY2021 −$0.20 —
FY2020 −$3.23 —
FY2019 $1.90 (8.21%)
FY2018 $2.07 —
FY2017 −$0.09 —
FY2016 −$0.50 —

Quarterly newest first

Period EPS (diluted) Change
Jun 2026 −$0.69 —
Mar 2026 −$0.56 —
Dec 2025 −$1.41 —
Sep 2025 −$0.80 —
42 more quarters

Against its own ten years

Low −$3.23 High $2.07
Ten-year median −$0.74
Current reading's percentile 36

EPS (diluted) against peers

What EPS (diluted) is

Diluted EPS tells an investor how much profit a company earned for each share, counting the extra shares that options and convertible securities could create.

Reported line item

The full definition of EPS (diluted) →

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